Virtual Biopsies with Handheld Dual-Axis Confocal Microscope

ChapterinIFMBE proceedings · May 2019with 14 Reads
DOI: 10.1007/978-981-10-9038-7_148
In book: World Congress on Medical Physics and Biomedical Engineering 2018, pp.805-808
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Abstract
We demonstrate a novel microelectromechanical system (MEMS) based Dual-Axes confocal (DAC) microscope in a 10-mm diameter handheld package. Miniaturization is achieved by using a barbell-shaped, gimbaled, two-dimensional (2-D) MEMS scanner that is actuated by self-aligned vertical comb actuators. The maximum DC optical scan angles are ±4.25° on the inner axis and ±1.5° on the outer axis, and the corresponding resonance frequencies are 3.4 and 1.2 kHz. The maximum imaging rate is 5 frames/s. The miniature DAC microscope operating at 785-nm-wavelength achieves full-width-half-maximum (FWHM) transverse and axial resolutions of 4.5 μm and 5 μm, respectively.

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