ArticlePDF Available

REVIEW ON MANUFACTURING PROTOCOL FOR MAHANARYAN OIL

March 2018
World Journal of Pharmacy and Pharmaceutical Sciences 7(4)

DOI:10.20959/wjpps20184-11231

Authors:

Azad Singh

Ananya Ayu Medicines

Varun Desale

Institute of Teaching and Research in Ayurveda

Mahanaryan oil is a classical oil formulation which was formulated in SAR SANGRAH and BHAISHAJ RATNAVALI, CHAPTER 26, VATAVYADHI ROGADHIKARA, Verse: 343 to 354 & BHAVAPRAKASHA CHIKITSA. Letter it is also published in Ayurvedic formulary of India in Second volume. This Article presents the importance about this oil. According to Ayurveda this oil is very important in Vattaj rogas/diseases. It is very useful in arthritis, paralysis and eye diseases, Facial palsy, Hearing loss, Deafness, Paraplegia, tremors, Neck rigidty, Lock jaw, wasting of hands, Female Infertility, Teeth and tongue ailment, headache, Dental pain, fever. It is also very effective in osteoporosis and osteo arthritis. It will balance the Vata and Pitta. It is highly used in panchkarma treatment in Anuvasana basti, Janubasti, Nasay. it is also orally in dose of 3 to 5ml twice a day, before food with warm water or milk. The shelf life of this oil is three year after date manufacture. It is very useful in migraine, headache, depression. It will nourish and rejuvenate our body. It can apply locally and used in deep tissue massage. Still there is lot of scientific search are pending on this oil. The active ingredient camphor makes it more beautiful formulation. saffaron is also improve the potency of the oil and make a colourful formulation. The Kalka ingredient is firstly prepared and then kawath dravya are added in it and milk is also added in it. I have prepared a large scale batch size table which is below in this article.

Content uploaded by Azad Singh

Content may be subject to copyright.

Content uploaded by Azad Singh

Content may be subject to copyright.

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

REVIEW ON MANUFACTURING PROTOCOL FOR MAHANARYAN

OIL

Singh Azad*, Desale Varun and Srivastava Prashant

IPGT and RA (Gujrat Ayurved University) Jamanagar, Gujrat India.

ABSTRACT

Mahanaryan oil is a classical oil formulation which was formulated in

SAR SANGRAH and BHAISHAJ RATNAVALI, CHAPTER 26,

VATAVYADHI ROGADHIKARA, Verse: 343 to 354 &

BHAVAPRAKASHA CHIKITSA. Letter it is also published in

Ayurvedic formulary of India in Second volume. This Article presents

the importance about this oil. According to Ayurveda this oil is very

important in Vattaj rogas/diseases. It is very useful in arthritis,

paralysis and eye diseases, Facial palsy, Hearing loss, Deafness,

Paraplegia, tremors, Neck rigidty, Lock jaw, wasting of hands, Female

Infertility, Teeth and tongue ailment, headache, Dental pain, fever. It is

also very effective in osteoporosis and osteo arthritis. It will balance the Vata and Pitta. It is

highly used in panchkarma treatment in Anuvasana basti, Janubasti, Nasay. it is also orally in

dose of 3 to 5ml twice a day, before food with warm water or milk. The shelf life of this oil is

three year after date manufacture. It is very useful in migraine, headache, depression. It will

nourish and rejuvenate our body. It can apply locally and used in deep tissue massage. Still

there is lot of scientific search are pending on this oil. The active ingredient camphor makes it

more beautiful formulation. saffaron is also improve the potency of the oil and make a

colourful formulation. The Kalka ingredient is firstly prepared and then kawath dravya are

added in it and milk is also added in it. I have prepared a large scale batch size table which is

below in this article.

KEYWORD: Ayurveda, formulation, kalk, kawath, vata, pitta, Fever.

INTRODUCTION

Mahanarayan tail or thaliam is ayurvedic classical medicated tail prepared by using till tail as

base and then processed in different medicate decoction and last aromatic drugs are mix in it

WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

SJIF Impact Factor 7.421

Volume 7, Issue 4, XXX-XXX Review Article ISSN 2278 – 4357

Article Received on

22 Jan. 2018,

Revised on 12 Feb. 2018,

Accepted on 04 March 2018

DOI: 10.20959/wjpps20184-11231

*Corresponding Author

Singh Azad

IPGT and RA (Gujrat

Ayurved University)

Jamanagar, Gujrat India.

azadaswal@gmail.com

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

It will improve the strength of bone and reduce the joint inflammation highly used in

osteoarthritis. Internally use this drug relief in knee pain. It will also reduce joint

inflammation. It is indicted in all types of VATA VYADI (Related to nerves, bones, muscles

and joints.[1,2] It is used in external application over the skin but in many Classical treatments

it is used internally such as Anuvasana basti, janubasti, Nasya. Orally It will balance the Vata

and Pitta.

For external used it can be long period of time and orally usage it is not more than the 3-4

months. Mahanarayan Thailam Fifty sex ingredient is which make this formulation special

and best. In which asthavarga drugs and animal origin drugs are added musk which makes

this drugs a pleasant smell and the kashar make it more valuable of this formulation.

According to Ayurvedic Pharmacopeia of India part One Second Edition best remedies of

these above disease Ardita (Facial palsy), Badhiratva (Deafness), Pagutva (Paraplegia), Gatra

Kampa (Tremors), Manya Stambha (Neck rigidity/Torricelli’s), Hanustambha (Lock jaw),

Ekanga (Wasting of one limb), Sukraksaya (Oligospermia), Vandhyatva (Infertility), Siroruja

(Headache), Jihvastambha (Glossal palsy), Danta sula (Dental Pain), Unmada

(Mania/Psychosis), Kubja (Hump-back/Kyphosis), Jvara (Fever), Jara (Senility/Progeriasis),

Karsya (Emaciation), Snayu Bhagna (Tendon tear), Asthi Bhagna (Bone fracture).[3] Lot of

experiment study done in animal but still there is more scientific research should done in this

lovely formulation. Inflammation is a complex network of a variety of molecules, which is

self-regulating through the balanced action of anti and pro inflammatory cytokines. An

imbalance between anti and pro-inflammatory cytokines results in cellular damage in

rheumatoid arthritis (RA), which is a common chronic inflammatory and destructive

arthropathy.[4,5] A study of anal sphincter tone in acute fissure in a patients treated with

mahanarayana oil was also done.[6] This oil also taken as reference standard activity for anti

inflammation.[7] It is also used in various composition for improve the therapeutic efficacy.[8]

it is also used in sinus therapy.[9] It is also used in psoriasis treatments.[10]

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

Diagrammatic View of different operation in preparation of Mahanarayan oil

OBSERVATION Table No. 1:- Manufacturing Method with Quantity.

Classical Preparation-: Ayurved Sar Sangrah

S.No

Process

Components Used / Added

Quantity

Pulverization-: Plant drugs are crushed

into yavkut powder.

Murchan Dravya

40.000

Kalka Dravya

148.000

Kwatha Dravya

520.000

Tail pak-: Measured quantity of

sesame tail taken. Tail pak done on

medium flame by

adding components

sequentially in Til tail.

512.00 Its

Weighted quantity of crushed herb

drugs are soaking into water and

poured into hot tail.

Murchan Dravya

40.000

Weighted quantity of crushed herb

drugs

are soaking into water and

poured into hot tail.

Kalka Dravya

148.000

Weighted quantity of crushed herb

drugs

are bottled into 16 times of

water and reduced to 1/4. filtered &

poured into hot

tail subsequently.

Kwatha

Shatavari kwath

1024.00 Its

Weighted quantity of milk poured

into hot tail.

Milk

512.00 Its

Filtration - manufactured oil filtered

into

Another vessel.

Mixing -: Volatile Materials are mixed

into

filtered tail

Kapoor

2.000

Keshar

2.000

Kankol (shital chini)

2.000

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

Table no. 2: Mahanarayan Oil (Mahanarayan Thailam) contains following ingredients.

S.NO

INGREDIENTS

QUANTITY (FOR PREPARATION)

Herbs for Decoction

Aegle Marmelos – Bilva (Indian Bael) root

1 Kg

Withania Somnifera – Ashwagandha (Indian Ginseng)

1 Kg

Solanum Indicum – Brihati (Indian Nightshade) root

1 Kg

Tribulus Terrestris – Gokshura

1 Kg

Oroxylum Indicum – Shyonaka

1 Kg

Sida Cordifolia Root – Bala (Country Mallow) root

1 Kg

Erythrina Variegata – Paribhadra or Azadirachta Indica – Neem

1 Kg

Solanum Xanthocarpum – Kantakari

1 Kg

Boerhavia Diffusa – Punarnava

1 Kg

Abutilon Indicum – Atibala (Indian Mallow)

1 Kg

Premna Serratifolia (Premna Mucronata & Premna Integrifolia)

– Agnimantha (Arani)

1 Kg

Paederia Foetida – Prasarini

1 Kg

Stereospermum Suaveolens – Patala

1 Kg

Water for making Decoction

100 liters

The decoction is prepared with above herbs and water is reduced to one fourth (i.e. 25 liters)

Base Oil

Sesamum Indicum – Sesame Oil (Til Tail)

6.4 liters

Goat Milk or Cow’s Milk

6.4 liters

Asparagus Racemosus – Shatavari Juice

6.4 liters

Herbs for Kalka (Paste)

Pluchea Lanceolata – Rasna

100 grams

Withania Somnifera – Ashwagandha (Indian Ginseng)

100 grams

Anethum Sowa – Mishi (Indian Dill) fruit

100 grams

Cedrus Deodara – Devdaru (Deodar Cedar or Himalayan Cedar)

100 grams

Saussurea Lappa – Kushta (Indian Costus Root)

100 grams

Desmodium Gangeticum – Shalaparni

100 grams

Uraria Picta – Prishnaparni

100 grams

Phaseolus Trilobus – Mudgaparni

100 grams

Teramnus Labialis – Mashaparni

100 grams

Aquilaria Agallocha – Agaru (Agarwood)

100 grams

Mesua Ferrea – Nagkesar

100 grams

Rock Salt (Sendha Namak or Halite)

100 grams

Nardostachys Jatamansi – Spikenard root

100 grams

Curcuma Longa – Haldi (Turmeric)

100 grams

Berberis Aristata – Daruhaldi

100 grams

Parmelia Perlata – Shaileyam

100 grams

Pterocarpus Santalinus – Lal Chandan (Red Sandalwood)

100 grams

Inula Racemosa – Pushkarmool

100 grams

Elettaria Cardamomum – Elaichi (Cardamom)

100 grams

Rubia Cordifolia – Manjistha (Indian Madder)

100 grams

Glycyrrhiza Glabra – Mulethi (Yashtimadhu or Licorice)

100 grams

Valeriana Wallichii – Tagara (Indian Valerian)

100 grams

Cyperus Rotundus – Mustak (Nut grass)

100 grams

Cinnamomum Tamala – Tejpata (Indian Bay Leaf)

100 grams

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

Eclipta Alba – Bhringraj

100 grams

Ashtavargam Herbs

Jivaka (Jeevak)

100 grams

Rishabhaka (Rishabhi)

100 grams

Meda

100 grams

Mahameda

100 grams

Kakoli

100 grams

Ksheera Kakoli

100 grams

Riddhi

100 grams

Vriddhi

100 grams

Pavonia Odorata – Ambu, Gandhbala

100 grams

Acorus Calamus – Vacha (Sweet flag)

100 grams

Butea Monosperma – Palash

100 grams

Clerodendrum Infortunatum – Titabhamt

100 grams

Boerhavia Erecta – Pandhari Punarnava (Shweta)

100 grams

Angelica Glauca – Choraka

100 grams

Cinnamomum camphor – Karpur

50 grams

Crocus Sativus – Kesar (Saffron)

50 grams

Kasturi (Musk)

50 grams

The mixture is boiled and simmered until the oil remains and filtered to get Maha Narayan Oil.

Shelf life / expiry date – Three years from the date of manufacture. Once opened, it is best to

empty the oil within 1 year.

CONCLUSION

Mahanarayan tail is well stabilised Classical formulation used in various treatments. It is very

beneficial in fever, arthritis, sinus, psoriasis. It should be used externally and internally. This

tail is also used for mixing with other composition so that the drug will increase its potency

and therapeutic efficacy. It is also taken as standard drugs in study of the inflammation

project.

REFERENCES

1. Vatavyadhi Rogadhikara, Bhaishajya Ratnavali, Chapter 26, Verse: 343 to 354, Page no

151 – 162.

2. Singh Jagdev Mahanarayan Oil (Mahanarayana Thailam), On May 5, 2016

https://www.ayurtimes.com/mahanarayan-oil-mahanarayana-thailam/.

3. Ayurvedic Pharmacopeia of India Part1 second edition, 8: 45 Page. no 436- 439.

4. Satyendra Kumar, Alka Madaan, Ritu Verma, Arun Gupta and J.L.N Sastri In vitro anti-

inflammatory effects of Mahanarayan oil formulations using dendritic cells based assay.

5. Sanjeev Rastogi Rehabilitative potential of Ayurveda for neurological deficits caused by

traumatic spinal cord injury. Int J Res Ayurveda Pharm, 2014 Jan-Mar; 5(1): 56–59.

www.wjpps.com Vol 7, Issue 4, 2018.

Singh et al. World Journal of Pharmacy and Pharmaceutical Sciences

6. Peshala, K. K. V. S., & Sahu, M. A study of anal sphincter tone in acute fissure in ano

patients treated with mahanarayana oil. Int J Res Ayurveda Pharm, 2014; 5: 318-321.

7. Killol S Chokshi, Jaimin S Suthar, Dilip Jani To Prepare Oil Containing Vitex Negundo

Extract Obtained Through Different Organic Solvents And Evaluate Its Anti-

inflammatory Activity By Topical Application, IOSR Journal of Pharmacy and Biological

Sciences (IOSRJPBS) ISSN: 2278-3008, Sep-Oct. 2012; 2(6): 22-24.

8. Vimal Patel, Winter Garden, FL (US), A61E36/9066 (2006.01) Merrima Tridentata

Compositions.

9. Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland,

Oregon, An Epidemic of Sinus Disorders, Aurveda Science of Life. DEC-2016.

10. Anurag and Bharadwaj Shreyasi, To Find Out The Effect of Matra Basti on Inflammation

In Patients Of Psoriasi, ejpmr, 2015; 2(5): 810-820.

Ameliorating effects of Clerodendrum viscosum leaves on lead‐induced hepatotoxicity

Article

Full-text available

Jun 2024

Lead (Pb), a common toxicant is ubiquitously present in the environment. Chronic Pb exposure affects almost every organ system of human body including liver. Clerodendrum viscosum is a medicinal plant and its leaves are known to have hepatoprotective, anti‐inflammatory, and anti‐hyperglycemic activities. However, the protective effect of C. viscosum leaves against Pb‐induced hepatotoxicity is yet to be studied. Therefore, this study was designed to assess the protective effect of the aqueous extract of C. viscosum leaf (Cle) against Pb‐induced hepatotoxicity in experimental mice. Pb‐acetate was given to Pb and Pb + Cle groups interperitoneally, and Cle was supplemented to Cle and Pb + Cle groups by oral gavage. Serum biomarkers of liver function—butyrylcholinesterase (BChE), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine transaminase (ALT), antioxidant enzyme activities in hepatic tissue—superoxide dismutase (SOD), reduced glutathione reductase (rGR) and catalase (CAT), levels of transcription factor—nuclear factor erythroid 2‐related factor 2 (Nrf2), and inflammatory marker—interleukin‐6 (IL‐6) were analyzed. Additionally, histological analyses of hepatic tissues of all groups of experimental mice were performed. Pb‐treatment significantly increased ALP, AST, and ALT activities and decreased BChE activity compared to control mice. The antioxidant enzyme (SOD, rGR, and CAT) activities and expression of Nrf2 level were significantly (p < .05) decreased, while IL‐6 level was significantly (p < .05) increased in the hepatic tissue homogenates of Pb‐treated mice compared to the control group. Furthermore, histological examination revealed the disruption of hepatic tissue integrity in Pb‐treated mice. Notably, supplementation of Cle provided significant protection against the changes in the activities of liver function biomarkers and antioxidant enzymes, levels of Nrf2 and IL‐6, and disruption of hepatic tissue by Pb. Taken together the present study suggests that Cle ameliorates the hepatic toxicity caused by Pb.

Clerodendrum viscosum leaves attenuate lead-induced neurotoxicity through upregulation of BDNF-Akt-Nrf2 pathway in mice

Article

Dec 2022
J ETHNOPHARMACOL

Ethnopharmacological relevance: Clerodendrum viscosum is an important medicinal plant in Ayurveda in Bangladesh and its leaves are used as a remedy for various diseases such as anti-inflammatory, antibacterial, hyperglycemic, hepatoprotective effects. Aim of the study: The present study aimed to evaluate the protective effect of aqueous extract of C. viscosum leaves against Pb-induced neurobehavioral and biochemical changes in mice. Materials and methods: Swiss albino mice were divided as a) control, b) lead treated (Pb) and c) C. viscosum leaves (Cle) d) Pb plus Cle groups. Pb-acetate (10 mg/kg body weight) was given to Pb and Pb + Cle groups mice, and water extract of leaves (50 mg/kg body weight) was provided as supplementation to Cle and Pb + Cle groups mice for 30 days. Elevated plus maze and Morris water maze tests were used for evaluating anxiety, spatial memory and learning, respectively. Status of cholinesterase, SOD, GSH enzyme activity and neurotoxicity markers such BDNF and Nrf2 levels were analyzed in the brain tissue of experimental mice. Results: Poorer learning, inferior spatial memory, and increased anxiety-like behavior in Pb-exposure mice were noted when compared to control mice in Morris water maze and elevated plus maze test, respectively. In addition, expression of BDNF and Nrf2, cholinesterase activity along with antioxidant activity were significantly reduced compared to control group (p < 0.01). Interestingly, C. viscosum leaves' aqueous extract supplementation in Pb-exposed mice provide a significant improved neurochemical and antioxidant properties through the augmentation of activity of cholinergic enzymes, and upregulation of BDNF and Nrf2 levels in the brain tissue compared to Pb-exposed mice. Conclusions: This study suggested that C. viscosum leaves restore the cognitive dysfunction and reduce anxiety-like behavior through upregulation of BDNF mediated Akt-Nrf2 pathway in Pb-exposure mice.

Clerodendrum viscosum: a critical review on phytochemistry, pharmacology, quality assurance, and safety data

Article

Full-text available

Oct 2021
MED CHEM RES

Clerodendrum viscosum Vent. is used in different indigenous systems of medicine by Asian ethnic communities. Significant advances in the validation of ethnomedicinal claims of C. viscosum are driving unprecedented opportunities for plant-based therapeutics leads and utilization of secondary metabolites for the mode of action studies. This study covered an updated and comprehensive review of the medicinal uses in traditional medicines, pharmacology, phytochemistry, and safety of C. viscosum. Extracts and phytoconstituents of C. viscosum have demonstrated a wide range of pharmacological effects such as anti-inflammatory, antioxidant, antidiabetic, anticancer, immunomodulatory, antibacterial, and hepatoprotection. More than 50 phytochemicals, representing the diverse classes of secondary metabolites that comprise both physiological and phytopharmaceutical significance, have been reported from C. viscosum. The molecules with terpenoids, flavonoids, steroids, and the glycosylated chemical scaffold and biological activities have demand in the pharmaceutical industry. An overview of the mechanism of action of prominent compounds has also been collated for future research on C. viscosum-based therapeutics.

Comprehensive Ayurvedic management of Sandhigatavata: a case report

Article

Full-text available

Jan 2019

Background: Osteoarthritis (OA) is the most common musculoskeletal abnormality. In Ayurveda, it is correlated with Sandhigatavata. Many studies have been conducted for the Ayurvedic management of Sandhigatavata but only with respect to clinical feature. Not a single evidence on their efficacy in radiological findings was available. So through this paper, efforts were taken for the successful Ayurvedic management of Sandhigatavata, evidenced over radiological findings. Aim: The aim of this study was to access the efficacy of Ayurvedic management including Shodhan (purification) and Shaman Chikitsa (palliative therapy) in Sandhigatavata. Materials and Methods: It is a single case study of a 50‑year‑old male patient who was diagnosed as case of Sandhigatavata with pain, stiffness, and swelling in right knee joint, difficulty while walking since 1 month. There was a significant joint space reduction with osteophytes in X‑ray of left knee joint. He was advised for local Abhyanga (massage), Swedana (hot fomentation), Niruha Basti (enema of herbal decoction), Janudhara (oil batch at knee joint), along with Lepa (local application of medicament) and palliative treatment. Results: After 1 month, changes were observed in symptoms, and reduction was seen in gross joint space in X‑ray of right knee joint. Conclusion: Patient got satisfactory relief in clinical features as well as in maintaining joint space, no overlapping of lateral epicondyle of femur and tibia, also no osteoporotic changes were observed in X‑ray after 1 month. Keywords: Ayurvedic management, osteoarthritis, Sandhigatavata

Sida cordifolia L.: Ethnobotany, Phytochemistry, Phytonanotechnology, and Commercial Application

Article

Full-text available

Oct 2023
CURR PHARM BIOTECHNO

Background After a period of prolonged indifference, where synthetic drugs were preferred, interest in the biological aspects and bioactive ingredients of plants accountable for therapeutic potential has been explored eminently. Sida cordifolia L. is a perennial herb that has been widely utilized in Indian (Ayurveda, Unani, and Siddha), American, and Chinese folk medicine and herbalism practice for curing a wide range of ailments in human beings. Objective The goal of this review is to elucidate indigenous knowledge parallelly with the pharmacotherapeutics potential of Sida cordifolia L. against various diseases. It is also intended to display pertinent information related to nanoparticle profiling. Methods In the current comprehensive study, web-based searches were performed by using several databases, such as Google Scholar, PubMed, ResearchGate, Science Direct, and Scopus, to figure out relevant research work and data published in academic journals from 1930 to July, 2023 using single or combination of keywords listed herewith. Results More than 50 chemical constituents, including quinazoline and phenethylamine alkaloids, flavones, flavonol, phytosterol, fatty acids, etc., were reported to be found in different parts of healthy plants. Apart from traditional claims and pharmacological aspects, several marketed herbal formulations and granted patents were also described. Conclusion Several in-vitro and in-vivo studies validated the usage of S. cordifolia as antiinflammatory, antibacterial, antifungal, antiprotozoal, anthelmintic, anticancer, antiulcer, cardioprotective, hypoglycemic, etc. agent. Few patents are also related to S. cordifolia, and more research work needs to be carried out for its potential granted to use as an antiviral agent and other new drug discovery molecules.

A study of anal sphincter tone in acute fissure in ano patients treated with mahanarayana oil

Article

Full-text available

Jul 2014

The internal anal sphincter (IAS) is an important structure which is responsible to maintain the resting tone. It is known to be responsible for occurrence of fissure in ano. Action of Mahanarayana oil on hypertonic sphincter was evaluated in this study. Three groups were formed with randomly selected forty five patients having symptoms of acute fissure in ano. There were fifteen patients in each group having the age between eighteen to seventy five years. Group I, the control group, was treated with Thriphala Guggulu, Hingvashtaka choorna, Powder Isabgol and sitz bath. Group II was treated with Ointment Diltiazem locally, with same regimen as in Group-I. Group III was treated with local application of Mahanarayana oil, with same regimen in Group - I. All the three groups were underwent ano rectal manometry procedure, before and after treatment by sixteen channel ano rectal manometry technique to evaluate resting pressure, squeeze pressure, volume of first sensation and Recto anal inhibitory reflex (RAIR). It was observed that resting pressure (mmHg) within group, compared by pair t test was significantly decreased in Group III after treatment as compared to Group II and I (100.87 ± 30.981SD vs 75.13 ± 12.489SD (P < 0.01), 85.60 ± 11.513SD vs 77.00 ± 9.150SD (P < 0.001) and 90.80 ± 11.803SD vs 88.47 ± 8.717SD (P > 0.05). Similarly, squeeze pressure, and Volume of first sensation etc. showed significant difference in Group III. Hence it can be concluded that Mahanarayana oil local application caused a significant decline in the Resting anal pressure with other parameters and also found to be better to relieve the acute spasm of anal sphincter in acute fissure in ano.

In vitro anti-inflammatory effects of Mahanarayan oil formulations using dendritic cells based assay

Article

Full-text available

Dec 2014

To Prepare Oil Containing Vitex Negundo Extract Obtained Through Different Organic Solvents And Evaluate Its AntiInflammatory Activitiy By Topical Application.

Article

Jan 2012

Killol S Chokshi

Sanjeev Rastogi Rehabilitative potential of Ayurveda for neurological deficits caused by traumatic spinal cord injury

Jan 2014
56-59

Sanjeev Rastogi Rehabilitative potential of Ayurveda for neurological deficits caused by traumatic spinal cord injury. Int J Res Ayurveda Pharm, 2014 Jan-Mar; 5(1): 56-59.

FL (US), A61E36/9066 (2006.01) Merrima Tridentata Compositions

Vimal Patel
Winter Garden

Vimal Patel, Winter Garden, FL (US), A61E36/9066 (2006.01) Merrima Tridentata Compositions.

An Epidemic of Sinus Disorders, Aurveda Science of Life

Jan 2016

Ph D Subhuti Dharmananda

Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon, An Epidemic of Sinus Disorders, Aurveda Science of Life. DEC-2016.

To Find Out The Effect of Matra Basti on Inflammation In Patients Of Psoriasi, ejpmr