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Penis Pump study.pdf

January 1995

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Cl Norman Shealy

International institute of Holistic Medicine

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Die Induratio penis plastica gehört zu den interessanten urologischen Erkrankungen, deren Ätiologie und Pathogenese und somit auch die Therapie noch nicht befriedigend geklärt sind. Veränderungen des Kollagenstoffwechsels werden diskutiert, traumatische Ursachen ebenfalls angenommen. Spontanremissionen werden beschrieben. Die Therapie unterscheidet eine konservative initiale Phase, die oft kein ... [Show full abstract] befriedigendes Ergebnis bringt, und verschiedene operative Eingriffe, die als wirksam aber symptomatisch anzusehen sind.

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Choline acetyltransferase (ChAT), a biochemical marker of cholinergic neurons, was measured in the erectile tissue of intact rats and in rats in which postganglionic fibers from the pelvic plexus were interrupted. ChAT activity in the denervated erectile tissue fell by 56% compared to control tissues. Acetylcholinesterase positive (AChE+) nerves also fell by about 48%. Penile neurons distal to ... [Show full abstract] the lesion probably account for the residual ChAT activity and remaining AChE+ nerve fibers in erectile tissue. These results indicate that acetylcholine is an important neurotransmitter in the regulation of penile erection.