The Effects of Rosmarinus officinalis L. Aqueous Extracts on Gastric Acid Secretion in Isolated Rats Stomach. Volkan Gelen, Emin Sengül, Fikret Çelebi, D.Ali Cınar. Department of Physiology, Faculty of Veterinary Medicine, University of Atatürk, Erzurum, Turkey Rosmarinus officinalis L. (Rosemary) has been shown to have antioxidant, anti-inflammatory and antiulces activites in different
... [Show full abstract] conditions.The present work was performed to investigate the possible effects of rosemary aqueous extracts on gastric acid secretion in isolated rats stomach.The stomachs of adult male Sprague-Dawley rats were removed.The stomach was placed in a 20-ml organ bath containing a serosal nutrient solution.Gastric acid secretion was measured from mucosal content in the isolated rat stomach.The results obtained in vitro experiments showed that doses of 300 µg/ml, 600 µg/ml and 1200 µg/ml of rosemary aqueous extracts have increased basal gastric acid secretion (except, 150 µg/ml).The present results suggest that rosemary may has a relieving effect on indigestion, probably due to increasing basal gastric acid secretion.