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THE TREATMENT OF EXTERNAL HEMORRHOIDS WITH NEW BIOAPIFIT HERBAL
ANTI-HEMORRHOIDAL OINTMENT
Oreščanin Višnja
OREŠČANIN Ltd., Laboratory for herbal drugs development, A. Jakšića 30, Zagreb, Croatia, vorescan@gmail.com
Hemorrhoid is defined as varicosities of the veins of the hemorrhoidal plexus, often complicated by inflammation, thrombosis, and
bleeding. It correlate positively with age and more than half of population of both sex aged 50 years and older will develop hemorrhoid
symptoms during their lifetime. Besides, the venous circulation disorders, chronic constipation, sedentary lifestyle, a diet low in fibers
are important risk factors for the occurrence of hemorrhoids. The prevalence of hemorrhoidal disease is estimated to be between 4.4%
and 12.8% in normal adult populations and about 40% in patients with symptoms of anal diseases. The most common symptoms are rectal
bleeding, pain associated with thrombosed hemorrhoids, and perianal pruritus. In this work we tested the efficacy of new multi-herbal
ointment for the treatment of external hemorrhoids.
INTRODUCTION
MATERIALS AND METHODS
RESULTS
CONCLUSION
Before the therapy the mean values and standard deviations for pain, defecation discomfort,
bleeding, itching and overall subjective discomfort were 7.2±0.8, 7.6±0.5, 2.7±0.7, 2.6±0.8 and
7.7±0.5, respectively. A significant decrease of all five parameters was obtained after only three days
of the treatment with mean values of 3.2, 3.4, 0.7, 0.9 and 2.9 for pain, defecation discomfort,
bleeding, itching and overall subjective discomfort, respectively. After five days of the therapy, there
was no pain or bleeding while the mean value for overall discomfort was 0.2. At 10th day of the
treatment all five parameters were graded 0 by all 50 patients. Obtained results could be linked with
the herbal composition with proven haemostatic, vasoconstrictor, astringent, anti-inflammatory and
wound healing potential.
Table 1. Frequences and percentages for the
selected variables of the tested population
50 patients ranging from 42 to 67 years with external hemorrhoids were treated 10 days (three times a day) with the herbal ointment
consisted of the following ingredients: the macerates of the plants Symphytum officinale, Plantago major, Calendula officinalis, Salvia
officinalis, Hypericum perforatum, Achillea millefolium, Polygonum aviculare, Bellis perennis, Quercus robur, Olea europaea, Urtica
dioica, Capsella bursa-pastoris, Matricaria chamomilla; essential oils Melaleuca alternifolia, Cympobogon martini, Origanum vulgare,
Eugenia caryophyllata, Thymus vulgaris ct. thymol, Cinnamomum camphora ct. cineol; Cera alba; honey and glycerol. The evaluation of
the patients before and following the therapy was done in terms of pain (0-10), defecation discomfort (0-10), bleeding severity (0-4), anal
itching severity (0-4) and overall subjective discomfort (0-10).
Figure 1. Pareto chart of t-values testing for
the influence of predictor variable onto overal
subjective discomfort of hemorrhoidal disease
before the treatment
Figure 2. Mean vales and standard deviations for score for each
symptoms of hemorrhoidal disease overal subjective discomfort
prior and following 3, 5 and 10 days of the treatment with
Bioapifit herbal anti-hemorrhoidal ointment
Variable
Group
N
%
Gender
F
25
50
M
25
50
Constipation
Y
40
80
N
10
20
Sedentary lifestyle
Y
40
80
N
10
20
Group
Age
BMI
X
SD
X
SD
Females
50.4
7.1
30.4
1.8
Males
54.6
9.6
35.8
4.3
Table 2. Mean values (X) and standard deviations (SD) for age and
body mass index (BMI) of the tested population
