Article

Difference Between Immunoglobulin and Antibody

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Abstract

Immunoglobulin and antibody are disease-fighting proteins developed by most vertebrates in response to a particular antigen. Both immunoglobulin and antibody are glycoproteins. Both of them contain similar regions in their molecules. Immunoglobulins are attached to the B cell membrane while antibodies float in the circulation. The main difference between immunoglobulin and antibody is that immunoglobulin has a transmembrane domain in order to be attached to the plasma membrane whereas antibody does not have a transmembrane domain. The five immunoglobulin classes are IgG, IgM, IgA, IgD, and IgE. An antibody is a Y-shaped glycoprotein. Immunoglobulins are also called surface immunoglobulins. Both immunoglobulin and antibody are components of the immune system.

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What is an Antibody?" News-Medical.net
  • Ananya Mandal
Mandal, Ananya. "What is an Antibody?" News-Medical.net, 3 Aug. 2017, Available here.
2221 Five Classes of Antibodies new" By OpenStax College -Anatomy & Physiology, Connexions Web site. Availabe here
  • Ananya Mandal
Mandal, Ananya. "What is an Antibody?" News-Medical.net, 3 Aug. 2017, Available here. Image Courtesy: 1. "Antibody" (CC BY-SA 2.5) via Commons Wikimedia 2. "2221 Five Classes of Antibodies new" By OpenStax College -Anatomy & Physiology, Connexions Web site. Availabe here, Jun 19, 2013. (CC BY 3.0) via Commons Wikimedia