Article

Copper‐Polymer Nanocomposite Catalyst for Synthesis of 1,4‐Diphenylbutadiyne‐1,3

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Abstract

A new catalyst for cross-coupling synthesis of 1,4-diphenylbutadiyne-1,3 was prepared by thermolysis of copper(II) poly-5-vinyltetrazolate. It presents heterogeneous catalyst, in which copper nanoparticles are supported on polymeric matrix surface. The catalyst is recovered, recycled, and shows high catalytic activity in cross-coupling synthesis of 1,4-diphenylbutadiyne-1,3. The reaction proceeds in aerobic conditions at room temperature in the presence of pyridine.

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... Классическим методом синтеза производных 1,2,3-триазола является катализируемая солями меди(I) реакция Хьюзгеновского [3+2]-циклоприсоединения азидов к терминальным алкинам [5]. Недавно нами показано, что эффективным катализатором этой реакции является продукт термического разложения поли-5-винилтетразолата меди, представляющий собой полимерную рентгеноаморфную матрицу с инкорпорированными наночастицами меди [6]. С использованием этого нового катализатора при комнатной температуре в водной среде с высоким выходом получен ряд 1,4-и 1,4,5-заме щенных-1Н-1,2,3-триазолов (рис. 1) [7], исследованию антибактериальной активности которых в отношении патогенного штамма Staphylococcus aureus, выделенного от пациента 1 , посвящена настоящая работа. ...
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  • Siemsen
  • Jiang
  • Aida
  • Campbell
  • I. D. Campbell
  • G. Eglinton
  • G. Eglinton
  • A. R. Galbraith