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«Primary», «basic» and «secondary» symptoms of schizophrenia in the concept of E. Bleuler

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Abstract

Two first works of swiss psychiatrist E. Bleuler that revise the symptomatology of Kraepelinian dementia praecox leaning on some findings of the psychoanalysis of S. Freud, C. Jung, F. Riklin, K. Abraham and on the P. Janet’s concept of psychasthenia are analyzed. The early concept of primary (testifying the direct organic lesion) and secondary (of psychogenic origin) symptoms of schizophrenia formulated by E. Bleuler is compared with his following concept of «basic» and «accessory» symptoms of schizophrenia. The concept of primary and secondary symptoms of schizophrenia was created firstly as a ground for the prognosis of the disease, and the concept of basic and accessory symptoms for the confident diagnosis of the disease. E. Bleuler’s concept accentuated the diagnosis of schizophrenia on the psychopathological and pathopsychological state of the patient, in contrast to E. Kraepelin’s concept of dementia praecox based on the course and outcome, made possible the expansion of schizophrenia boundaries at the expense of different psychotic and nonpsychotic disorders that other authors attributed to the forms of «degenerative madness», neuroses and psychopathies.

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Negative symptoms of schizophrenia represent, at the present stage of their study, a certain group of mental pathology. They include motivation disorders or volitional disorders (anhedonia, abulia, asociality) and disorders of reduced expression or emotional disorders (alogia/poverty of speech and emotional decline/flattening). Negative symptoms are key disorders in schizophrenia, often appear at the pre-manifest stage of the disease, and significantly affect the prognosis and response to therapy. From a scientific and practical point of view, it is important to distinguish between primary and secondary negative symptoms, where the primary symptoms are nuclear, inherent in schizophrenia, and the secondary ones are the result of the influence of positive symptoms (delusions, hallucinations), depression, side-effects of medications, social isolation and hospitalism. Changes in the concept of primary and secondary negative disorders as well as a pathophysiological basis of negative symptoms are considered.
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On the 100th anniversary of the publication of Eugen Bleuler's Dementia Praecox or the Group of Schizophrenias, his teachings on schizophrenia from that seminal book are reviewed and reassessed, and implications for the current revision of the category of schizophrenia, with its emphasis on psychotic symptoms, drawn. Bleuler's methods are contrasted with Kraepelin's, and 4 myths about his concept of schizophrenia addressed. We demonstrate that (1) Bleuler's concept of schizophrenia has close ties to historical and contemporary concepts of dissociation and as such the public interpretation of schizophrenia as split personality has some historical basis; (2) Bleuler's concept of loosening of associations does not refer narrowly to a disorder of thought but broadly to a core organically based psychological deficit which underlies the other symptoms of schizophrenia; (3) the “4 A's,” for association, affect, ambivalence, and autism, do not adequately summarize Bleuler's teachings on schizophrenia and marginalize the central role of splitting in his conception; and (4) Bleuler's ideas were more powerfully influenced by Pierre Janet, particularly with regard to his diagnostic category Psychasthenia, than by Sigmund Freud. We conclude that Bleuler's ideas on schizophrenia warrant reexamination in the light of current criticism of the emphasis on psychotic symptoms in the schizophrenia diagnosis and argue for the recognition of the dissociative roots of this most important psychiatric category.
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The author analyzes the features of the syndrome of «delusional fantasies» (delusion-like fantasies) in the concept of K. Birnbaum. According to this concept, psychopathic constitutions, due to the presence in the structure of dissociation, are the basis for the development of delusions per se. «Dreamer» and «vershroben» types are predisposed to the syndrome of «delusional fantasies». It is emphasized that initially the syndrome of «delusional fantasies» was described as a peculiar phasic episode of delusions in psychopaths, aged between 20-30 years. In the current domestic literature, delusion-like fantasies are regarded as non-delusional bizarre fantastic ideas in children and adolescent patients.
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The author analyzed a symptom concept of Th. Ziehen that had competed with the Kraepelin nosological concept of mental disorders. The classification of psychopathological constitutions and defective states in mental diseases used by Th. Ziehen is discussed. The particular significance given by Th. Ziehen to overvalues in the formation of psychopathological phenomena and sexual perversions as major characteristics of the general type of inherited psychopathic constitution is emphasized. The Th. Ziehen’s definition of psychopathic constitution is compared to Kraepelin’s conception of psychopathic personality.
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The author analyze conceptions of mental signs of predisposition (diathesis, vulnerability) to non-psychotic and delusional mental disorders of functional origin described in the works of leading French psychiatrists of the late 19th/early 20th centuries (E. Regis, P. Serieux, J. Capgras, E. Dupre, J. Levy-Valensi etc). The descriptions of characteristics of some constitutional types and the differences in the structure of constitutional types and the structure of delusional disorders developed on their basis are compared.
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