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Nature and Science of Sleep 2017:9 181–186
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ORIGINAL RESEARCH
open access to scientific and medical research
Open Access Full Text Article
http://dx.doi.org/10.2147/NSS.S136467
Total sleep time, alcohol consumption, and the
duration and severity of alcohol hangover
Marith van Schrojenstein
Lantman1
Marlou Mackus1
Thomas Roth2
Joris C Verster1,3,4
1Utrecht Institute for Pharmaceutical
Sciences, Division of Pharmacology,
Utrecht University, Utrecht, The
Netherlands; 2Sleep Disorders
and Research Center, Henry Ford
Health System, Detroit, Michigan,
USA; 3Institute for Risk Assessment
Sciences (IRAS), Utrecht University,
Utrecht, The Netherlands; 4Centre
for Human Psychopharmacology,
Swinburne University, Melbourne VIC,
Australia
Introduction: An evening of alcohol consumption often occurs at the expense of sleep time.
The aim of this study was to determine the relationship between total sleep time and the dura-
tion and severity of the alcohol hangover.
Methods: A survey was conducted among Dutch University students to collect data on their
latest alcohol hangover. Data on alcohol consumption, total sleep time, hangover severity,
and duration were collected. Alcohol consumption and hangover severity and duration were
compared for participants who (a) slept <5 hours, (b) slept between 5 and 7 hours, or (c) slept
>7 hours.
Results: Data from N=578 students (40.1% men and 59.9% women) were included in the
statistical analyses. Significant correlations were found between total sleep time and alcohol
consumption (r=0.117, p=0.005), hangover severity (r= –0.178, p=0.0001) and hangover duration
(r=0.168, p=0.0001). In contrast, total alcohol consumption did not correlate significantly with
overall hangover severity or duration. Those who slept longer than 7 hours consumed significantly
more alcohol (p=0.016) and reported extended hangover duration (p=0.004). However, they
also reported significantly less severe hangovers (p=0.001) than students who slept <7 hours.
Conclusion: Reduced total sleep time is associated with more severe alcohol hangovers.
Keywords: alcohol, hangover, duration, severity, total sleep time
Introduction
Due to next-day commitments, an evening of alcohol consumption often occurs at the
expense of total sleep time. The most frequently reported consequence of heavy alcohol
consumption is the alcohol hangover. The alcohol hangover refers to the combination
of mental and physical symptoms, experienced the day after a single episode of heavy
drinking, starting when blood alcohol concentration approaches zero.1
Only a few studies have investigated the relationship between heavy alcohol con-
sumption and subsequent sleep, and impact on next day functioning and mood. Finnigan
et al examined the next-day effects of consuming alcohol (blood alcohol concentration
[BAC] 0.10%) on psychomotor performance, subjective state, and quality of sleep.2
In this double-blind placebo-controlled study of 40 men who were moderate-to-heavy
social drinkers, no significant effects were found on psychomotor performance. How-
ever, after consuming alcohol subjects fell asleep faster, and reported reduced alertness
during the hangover state. McKinney and Coyle examined mood and anxiety in 48 social
drinkers the day after heavy drinking, and on an alcohol-free control day.3 Applying a
naturalistic study design, subjects consumed the amount, type of alcohol at their own
pace and venue of choice, without the presence of the investigators. However, they were
Correspondence: Joris C Verster
Utrecht Institute for Pharmaceutical
Sciences, Division of Pharmacology,
Utrecht University, Universiteitsweg 99,
3584 CG, Utrecht, The Netherlands
Tel +31 30 253 6909
Fax +31 30 253 7900
Email j.c.verster@uu.nl
Journal name: Nature and Science of Sleep
Article Designation: ORIGINAL RESEARCH
Year: 2017
Volume: 9
Running head verso: van Schrojenstein Lantman et al
Running head recto: Sleep and alcohol hangover
DOI: http://dx.doi.org/10.2147/NSS.S136467
This article was published in the following Dove Press journal:
Nature and Science of Sleep
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asked to limit drinking to between 10 pm and 2 am, but there
were no restrictions placed on the subjects, sleep behavior.
Heavy alcohol consumption had a negative impact on next-
day mood including increased anxiety levels. Disrupted
sleep was reported after alcohol consumption and fatigue
was significantly increased during the hangover state. These
data illustrate that drinking goes at the expense of sleep.
In the alcohol condition subjects went to bed significantly
later when compared to the alcohol-free day, resulting in a
significantly reduced total sleep time. The higher the intake
of alcohol, the shorter the corresponding sleep latency. After
alcohol, subjects qualified their sleep as less satisfying,
refreshing, or restful. Rohsenow et al investigated the impact
of heavy drinking on hangover, perceived sleep, and next-
day ship power plant operation.4 Maritime academy cadets
(n=61) consumed alcohol to achieve a BAC of 0.115%. Next
morning, 8 hours thereafter, they were tested. No significant
difference relative to the alcohol-free test day was observed in
performance on the diesel power plant simulator. While total
sleep time was not affected by alcohol consumption, subjects
reported significantly improved sleep quality and reduced
sleep latency after alcohol. In a subsequent study, Rohsenow
et al again examined the effects of heavy alcohol consumption
on sleep and neurocognitive functioning.5 This study further
examined whether drinks with low and high congener content
(vodka versus bourbon, respectively) had a differential impact
on sleep, and next-day hangover severity and performance
outcomes. Young, heavy, social drinkers (n=95) participated
in this double-blind study. After consuming alcohol to achieve
a BAC of 0.11%, subjects went to bed. Sleep was monitored
using polysomnography. During hangover, neurocognitive
performance showed significant impairment on tests combin-
ing sustained attention and rapid responding. Hangover sever-
ity correlated with poorer performance. Polysomnographic
assessments revealed that alcohol consumption decreased
sleep efficiency and rapid eye movement sleep, and increased
wake time and next-day self-reported sleepiness. Hangover
severity was significantly worse in subjects with reduced
sleep efficiency, and subjects with higher hangover severity
scores had a reduced total sleep time and spent less time in
rapid eye movement sleep. No significant difference on sleep
or performance outcomes was observed for drinks with low
or high congener content. However, hangover severity was
significantly worse after consuming bourbon. No significant
gender differences were observed.
Together, the findings from these studies support the
hypothesis that the interrelationship between heavy alcohol
consumption and subsequent sleep quality and duration may
have a significant impact on next day hangover severity, perfor-
mance impairment, and mood disturbances. Therefore, the aim
of the current analyses was to further examine the relationship
between total sleep time and sleep quality, and the duration and
severity of the alcohol hangover. To determine this, data from
Penning et al was analyzed from a survey on alcohol hangover.6
Methods
Dutch students were approached at different locations on
the campus of Utrecht University, and asked to complete a
retrospective survey. Written informed consent was obtained
from all participants; no formal ethics approval was required
to conduct this type of survey research, according to the
Central Committee on Research Involving Human Subjects
(CCMO). There was no participation rate recorded, but the
vast-majority of students were willing to complete the survey.
Data were collected on alcohol consumption during their
latest heavy drinking session, subsequent total sleep time,
and next day hangover severity. Overall hangover severity
was reported at every 2 hours after waking up (starting 4 am
until midnight). At each time point, participants could rate
their hangover severity on a scale ranging from 0 (absent)
to 10 (extreme). The area under the curve was computed to
reflect overall hangover severity, ranging from 0 (absent)
to 111 (extreme). In addition, the severity of 47 individual
hangover symptoms was scored on a scale ranging from 0
(absent) to 10 (extreme). 6
The number of alcoholic drinks consumed was recorded,
as was the start and stop time of drinking. This information,
together with data on body weight and gender, was used to
compute the estimated peak BAC (eBAC), using the modified
Widmark formula.7 Finally, start and stop time of sleep was
recorded to calculate total sleep time (TST).
Statistical analyses were conducted with SPSS, version
24 (IBM Corp., Armonk, NY, USA). Alcohol consump-
tion, hangover severity, and duration were compared for
participants who (1) slept <5 hours, (2) slept between 5 and
7 hours, or (3) slept >7 hours. Subjects were included in the
analyses if they were aged 18–30 years and reported having
a hangover after consuming alcohol during the past month.
Results
Data from 578 students (40.1% men and 59.9% women) were
included in the statistical analyses. Their mean (SD) age was
20.0 (2.1) years and they consumed 20.5 (17.3) alcoholic
drinks weekly. On average, they experience 2.7 (2.4) hangover
days per month. On their latest heavy drinking occasions, they
consumed 8.3 (5.8) alcoholic drinks to achieve a mean (SD)
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Sleep and alcohol hangover
eBAC of 0.10 (0.1) %. The average duration of hangover since
their last drink was 18.4 (3.9) hours. The drinking session
was followed on average by 6.5 (2.1) hours of sleep. Table 1
summarizes the demographic data of the sample.
TST correlated significantly with hangover severity
(r=0.178, p=0.0001) and duration (r=0.168, p=0.0001),
total alcohol consumption (r=0.117, p=0.005), and eBAC
(r=0.123, p=0.003). As expected, eBAC correlated signifi-
cantly with alcohol consumed on the heavy drinking occa-
sion (r=0.806, p =0.0001) and weekly alcohol consumption
(r=0.302, p=0.0001). Weekly alcohol consumption also
significantly related to the number of alcoholic drinks con-
sumed on the latest heavy drinking occasion that resulted
in a hangover (r=0.530, p=0.0001). However, eBAC did
not significantly correlate with hangover severity (r=0.018,
p=0.664) or duration (r= –0.006, p=0.895). Similarly, total
alcohol consumption also did not significantly correlate with
overall hangover severity (p=0.953) and duration (p=0.563).
The majority of students (N=313) slept between 5 and
7 hours. Those who slept longer than 7 hours consumed
significantly more alcohol (9.3 versus 7.9 and 7.7 drinks,
p=0.016), reported extended hangover duration (19.2 versus
18.3 and 17.5 hours, p=0.004), but reported significantly
less severe hangovers (20.9 versus 23.9 and 27.5, p=0.001)
than students who slept 5–7 hours or <5 hours, respectively
(see Table 1).
When compared to men, women consumed significantly
less alcohol weekly (15.7 versus 27.7 drinks, p=0.0001),
and significantly less alcohol on their latest heavy drinking
episode (5.8 versus 12.0 drinks, p=0.0001). Accordingly,
eBAC was significantly lower in women when compared to
men (0.08% versus 0.13%, p=0.0001). Also, women slept
significantly shorter hours than men (6.2 versus 6.9 hours,
p=0.0001). However, the short TST, lower amounts of alco-
hol consumed, and eBAC were not reflected in significant
differences between women and men in hangover duration
(18.6 versus 18.1 hours, p=0.167) and hangover severity (24.5
versus 22.2, p=0.056).
Individual symptoms
TST correlated significantly with fatigue (r= –0.166,
p=0.0001), sleepiness (r= –0.118, p=0.005), reduced appetite
(r= –0.105, p=0.012), stomach pain (r= –0.098, p=0.020),
respiratory problems (r= –0.84, p=0.045), and impulsivity
(r= –0.083, p=0.049). Individual symptom severity scores
for each sleep group are summarized in Table 2.
Those with a TST over 7 hours reported significantly
less severe scores on fatigue (p=0.032) and feeling guilty
(p=0.038) when compared to those who slept 5 to 7 hours,
and significantly less severe scores on fatigue (p=0.0001),
sleepiness (p=0.004), and respiratory problems (p=0.005)
Table 1 Demographics of subjects
Overall <5 h sleep 5–7 h sleep >7 h sleep
Number of subjects (%) 578 (100) 95 (16.4) 313 (54.2) 170 (29.4)
Age (years) 20.0 (2.1) 19.7 (2.1) 19.9 (2.1) 20.5 (2.2)a
Weekly number of alcoholic drinks 20.5 (17.3) 16.3 (13.6) 20.4 (17.1) 23.1 (19.2)a
Number of hangovers per month 2.7 (2.4) 2.1 (1.7) 2.7 (2.6) 2.9 (2.4)
Number of alcoholic drinks on heavy drinking session 8.3 (5.8) 7.7 (5.5) 7.9 (5.5) 9.4 (6.3)b
eBAC (%) 0.10 (0.10) 0.08 (0.09) 0.10 (0.10) 0.12 (0.12)a
Hangover severity 23.5 (13.9) 27.5 (16.5) 23.9 (13.4) 20.9 (12.5)a
Hangover duration (h) 18.4 (3.9) 17.5 (4.4) 18.3 (3.7) 19.2 (3.9)a
Total sleep time (h) 6.5 (2.1) 3.4 (0.9) 6.0 (0.7) 9.0 (1.4)a–c
Notes: The hangover severity score ranges from 0 (absent) to 111 (extreme). aSignicant difference (p<0.05) between <5 h sleep group and >7 h sleep group; bsignicant
difference (p<0.05) between 5–7 h sleep group and >7 h sleep group; csignicant difference (p<0.05) between <5 h sleep group and 5–7 h sleep group.
Abbreviation: eBAC, estimated blood alcohol concentration.
Figure 1 Associations of total sleep time with alcohol consumption and the severity
and duration of the alcohol hangover.
Notes: Only signicant associations (p<0.05) are depicted. Red line indicates a
negative correlation; blue line indicates a positive correlation.
Abbreviation: eBAC, estimated blood alcohol concentration.
eBAC
Hangover
severity
Hangover
duration
Alcohol
on heavy
drinking
occasion
Total
sleep
time
Alcohol
per week
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van Schrojenstein Lantman et al
when compared to those who slept <5 hours. Compared to
those who slept <5 hours, those who slept 5 to 7 hours had
significantly less severe scores on fatigue (p=0.012), sleepi-
ness (p=0.011), respiratory problems (p=0.007), suicidal
thoughts (p=0.009), and pounding heart (p=0.046).
Discussion
Our study confirms that drinkers with reduced TST report
higher hangover severity scores after a night of heavy drinking.
Subjects who slept longer than 7 hours consumed significantly
more alcohol and reported an extended hangover duration.
Table 2 Individual hangover symptoms and their severity
Factor Symptoms Overall <5 h 5–7 h >7 h
1 Drowsiness Drowsiness 5.8 (2.9) 5.8 (3.1) 5.8 (2.8) 5.6 (3.0)
Fatigue 6.5 (2.6) 7.1 (2.7) 6.6 (2.4)c6.0 (2.7)a,b
Sleepiness 5.6 (3.1) 6.4 (3.0) 5.5 (3.0)c5.3 (3.1)a
Apathy 4.2 (3.3) 4.3 (3.5) 4.1 (3.2) 4.3 (3.4)
Weakness 4.4 (3.1) 4.4 (3.3) 4.5 (3.1) 4.4 (3.3)
2 Cognitive problems Confusion 1.1 (2.2) 1.0 (2.2) 1.1 (2.2) 1.3 (2.3)
Disorientation 1.4 (2.4) 1.3 (2.3) 1.4 (2.4) 1.6 (2.5)
Increased reaction time 3.4 (2.8) 3.4 (2.9) 3.3 (2.7) 3.6 (2.8)
Reduced alertness 3.7 (2.8) 3.5 (3.0) 3.7 (2.7) 3.9 (2.8)
Concentration problems 4.0 (3.3) 4.0 (3.2) 4.2 (3.0) 3.9 (3.0)
Memory problems 2.3 (2.9) 2.4 (2.9) 2.2 (2.9) 2.4 (3.0)
Clumsiness 2.2 (2.7) 2.1 (2.6) 2.2 (2.7) 2.2 (2.7)
3 Disturbed water balance Muscle pain 1.5 (2.5) 1.7 (2.6) 1.5 (2.6) 1.2 (2.5)
Dry mouth 5.1 (3.2) 5.0 (3.3) 5.0 (3.2) 5.3 (3.1)
Thirst 5.9 (3.0) 6.2 (2.9) 5.7 (3.1) 6.1 (2.8)
Tremor 1.9 (2.7) 2.2 (3.1) 1.9 (2.7) 1.7 (2.6)
Shivering 1.5 (2.5) 2.0 (2.8) 1.4 (2.4) 1.4 (2.4)
Sweating 1.4 (2.4) 1.6 (2.4) 1.5 (2.5) 1.2 (2.1)
Hot/cold ashes 0.9 (2.1) 0.9 (2.0) 1.0 (2.2) 0.8 (1.8)
Nystagmus 0.6 (1.6) 0.7 (1.5) 0.7 (1.8) 0.6 (1.6)
4 Mood disturbances Depression 0.8 (2.0) 1.0 (2.4) 0.7 (1.8) 0.9 (2.0)
Anxiety 0.3 (1.1) 0.4 (1.4) 0.3 (1.1) 0.3 (1.1)
Anger 0.3 (1.1) 0.4 (1.2) 0.3 (1.2) 0.3 (0.9)
Agitation 2.0 (2.6) 1.6 (2.2) 2.1 (2.6) 2.1 (2.6)
5 Balance problems Balance problems 1.6 (2.5) 1.5 (2.4) 1.5 (2.5) 1.7 (2.5)
Dizziness 2.0 (2.8) 2.5 (3.2) 2.0 (2.7) 1.9 (2.7)
Vertigo 1.9 (2.8) 2.3 (3.1) 1.8 (2.7) 1.9 (2.7)
Tinnitus 0.6 (1.7) 0.7 (1.7) 0.6 (1.7) 0.7 (1.7)
6 Gastrointestinal problems Nausea 4.6 (3.3) 4.5 (3.4) 4.7 (3.2) 4.5 (3.4)
Stomach pain 2.0 (2.7) 2.3 (3.0) 2.1 (2.8) 1.6 (2.5)
Gastrointestinal complaints 2.2 (2.9) 2.3 (3.1) 2.3 (2.9) 2.0 (2.9)
Gastritis 1.1 (2.3) 1.2 (2.3) 0.9 (2.1) 1.3 (2.5)
7 Respiratory and cardiovascular problems Palpitations 0.7 (1.9) 0.9 (2.1) 0.6 (1.8) 0.8 (1.8)
Pounding heart 0.8 (1.9) 1.1 (2.3) 0.7 (1.9)c0.7 (1.7)
Respiratory problems 0.4 (1.3) 0.8 (2.0) 0.3 (1.3)c0.2 (0.9)a
8 Impulsivity and blunted affect Restlessness 1.6 (2.6) 1.9 (3.0) 1.6 (2.5) 1.6 (2.6)
Blunted affect 1.3 (2.3) 1.4 (2.3) 1.3 (2.3) 1.3 (2.4)
Impulsivity 0.9 (2.1) 1.3 (2.5) 0.8 (2.0) 0.9 (2.1)
Loss of taste 1.1 (2.1) 1.6 (2.7) 0.9 (1.9) 1.2 (2.2)
9 Vomiting and feeling guilty Vomiting 1.3 (2.9) 1.2 (2.8) 1.2 (2.8) 1.6 (3.1)
Regret 1.2 (2.4) 1.3 (2.7) 1.1 (2.2) 1.3 (2.5)
Guilt 1.1 (2.2) 1.5 (2.7) 0.9 (1.9) 1.3 (2.4)b
Reduced appetite 3.4 (3.4) 4.1 (3.8) 3.3 (3.3) 3.2 (3.5)
10 Headache Headache 5.0 (3.1) 5.0 (3.1) 5.0 (3.1) 5.1 (3.1)
Photosensitivity 1.4 (2.4) 1.3 (2.4) 1.4 (2.3) 1.4 (2.4)
Audio sensitivity 1.4 (2.3) 1.3 (2.6) 1.4 (2.2) 1.5 (2.4)
11Suicidal thoughts Suicidal thoughts 0.1 (0.8) 0.3 (1.5) 0.0 (0.3)c0.1 (0.8)
Notes: Data represented as mean (SD). Symptoms are grouped according to the factor analysis. Data from Penning et al.6 aSignicant difference (p<0.05) between <5 h sleep
group and >7 h sleep group; bsignicant difference (p<0.05) between 5–7 h sleep group and >7 h sleep group; csignicant difference (p<0.05) between <5 h sleep group and
5–7 h sleep group.
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Sleep and alcohol hangover
However, at the same time they reported having significantly
less severe hangovers. The latter suggests that sleep has a
positive effect on relieving alcohol hangover. TST was most
strongly related to sleep-related individual hangover symptoms
such as fatigue and sleepiness. Interestingly, short versus nor-
mal and long sleep did not significantly differ in severity scores
of most commonly reported hangover symptoms. This obser-
vation demonstrates that some frequently reported hangover
symptoms associated with moderate to high severity scores
such as nausea and headache are independent of possible acute
sleep deprivation after an evening of alcohol consumption.
Those with the shortest sleep durations consumed sig-
nificantly less alcohol and had a much lower eBAC. From
the present methodology, it is not possible to determine
whether drinkers were aware of having limited time in bed,
for example, due to a scheduled appointment next morning,
and therefore reduced their alcohol intake relative to those
who had the opportunity of unrestricted sleep. Future research
should further investigate the impact of restricted versus
unrestricted sleep opportunity on alcohol consumption and
the severity and duration of the alcohol hangover.
A limitation of this study was that TST was the only sleep
outcome assayed. No information was collected on sleep qual-
ity, nightly awakenings, time to sleep onset, or other potentially
relevant parameters. Also, no objective measurements such
as polysomnography or actigraphy were made to strengthen
our observations. Future research using a prospective study
design should implement the objective assessments. Apply-
ing a prospective study design would also eliminate possible
recall bias, which is always an issue in retrospective survey
research. It would also be of interest to include psychometric
assessments in future studies. Although it is known that cog-
nitive and psychomotor functioning and daily activities such
as driving a car may be impaired during alcohol hangover,8,9
the impact of variations in TST on performance during the
hangover state has not received adequate research attention.
The observation that TST is significantly related to hangover
severity does however predict that variations in TST may also
affect daily activities during the hangover state such as driving
a car or job performance. Finally, it should be kept in mind that
the direction of the association between total sleep time and
alcohol consumption and hangover severity is unknown. From
the current survey data, cause and effect cannot be determined.
Conclusion
The current data confirm that an evening of heavy drinking
often occurs at the expense of total sleep time. Reduced sleep
time is associated with more severe hangovers.
Acknowledgment
An abstract containing interim findings of this paper was
presented as a poster at the 2014 British Association for
Psychopharmacology meeting. The poster’s abstract was
published in Journal of Psychopharmacology 2014, 28
(supplement to #8): A19.
Disclosure
Joris C Verster has received grants/research support from
the Dutch Ministry of Infrastructure and the Environment,
Janssen, Nutricia, Red Bull, and Takeda, and has acted
as a consultant for the Canadian Beverage Association,
Centraal Bureau Drogisterijbedrijven, Coleman Frost,
Danone, Deenox, Eisai, Janssen, Jazz, Purdue, Red Bull,
Sanofi-Aventis, Sen-Jam Pharmaceutical, Sepracor, Takeda,
Transcept, Trimbos Institute, and Vital Beverages. Thomas
Roth has received grants/research support from Aventis,
Cephalon, GlaxoSmithKline, Neurocrine, Pfizer, Sanofi,
Schering-Plough, Sepracor, Somaxon, Syrex, Takeda, Trans-
Oral, Wyeth, and XenoPort and has acted as a consultant for
Abbott, Acadia, Acoglix, Actelion, Alchemers, Alza, Ancil,
Arena, AstraZeneca, Aventis, AVER, BMS, BTG, Cephalon,
Cypress, Dove, Elan, Eli Lilly, Evotec, Forest, Glaxo Smith
Kline, Hypnion, Impax, Intec, Intra-Cellular, Jazz, Johnson
& Johnson, King, Lundbeck, McNeil, MediciNova, Merck,
Neurim, Neurocrine, Neurogen, Novartis, Orexo, Organon,
Prestwick, Procter & Gamble, Pfizer, Purdue, Resteva, Roche,
The other authors report no conflicts of interest in this work.
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