Risk Factors for Lipemic Plasma in Blood Donors

Abstract

Background: Donated blood with lipemic plasma must be discarded because of inappropriate use for the patients. In addition, the lipemic plasma may increase hemolysis rate of red cells and may leading to false negative result of infectious screening tests. If blood donor can self-risk evaluate of lipemic plasma and defer themselves to donate blood, it may reduce plasma discarding. Objective: This study aims to identify the risk factors for lipemic plasma in blood donors, and to compare the hemolysis rate between red cells kept in lipemic plasma and normal plasma. Methods: The subjects are blood donors who donated blood at Nongkhai hospital. The lipemic plasma was determined by visual inspection. The risk factors were evaluated from questionnaire. The level of triglyceride and cholesterol in the sera were determined. The hemolysis rate of red cells was evaluated by the ratio of hemoglobin concentration in plasma and the whole blood. Results: A total 392 plasma samples consisted of 41 with lipemic and 351 with normal plasma. Sex, age, body mass index, and triglyceride levels, were associated with lipemic plasma. Male was associated with increased risk than female (Odds ratio (OR) 3.10; 95% confident interval (CI): 1.55-6.18). Age greater than 35 years had higher prevalence than age ≤ 35 years in lipemia (OR 2.50; 95%CI: 1.29-4.85). Body mass index (BMI) ≥ 25.0 kg/m2 had higher risk than BMI < 25.0 kg/m2 (OR 2.69; 95%CI: 1.39-5.19). Sera triglyceride level of 151-300 mg/dL and > 300 mg/dL had higher risk than triglyceride level 0-150 mg/dl (OR 8.05; 95%CI: 3.10-20.9 and OR 58.3; 95%CI: 19.5-175, respectively). In addition, red cells kept in lipemic plasma showed significantly higher levels of hemolysis rate than red cells in normal plasma after 7 days storage (p = 0.012). Conclusion: Lipemic plasma could lead to the shorter age of red cells. Also, the risk factors for lipemia: sex, age and BMI might be used as guideline for donation without lipemic plasma to avoid blood discarding

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วารสารโลหิตวิทยาและเวชศาสตรบริการโลหิต ป ที่ 27 ฉบับ ที่ 2 เมษายน-มิถุนายน 2560
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
คำาสำาคัญ :lll
วารสารโลหิตวิทยาและเวชศาสตร์บริการโลหิต 2560;27:117-25.

ประไพนิล แก้วด้วง และคณะ
J Hematol Transfus Med Vol. 27 No. 2 April-June 2017






Abstract:
Background:


 Objective: 

 Methods:


 Results: 


≤
≥



 Conclusion:


Keywords :lll
J Hematol Transfus Med 2017;27:117-25.


วารสารโลหิตวิทยาและเวชศาสตรบริการโลหิต
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
 
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




ประไพนิล แก้วด้วง และคณะ
J Hematol Transfus Med Vol. 27 No. 2 April-June 2017
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
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


  






วารสารโลหิตวิทยาและเวชศาสตรบริการโลหิต



 




p value
   
    
   

    
   
   
   

    
   
≥   

    
   

    
   

    
   

    
   






 p value

    
   
   

    
   
   

ประไพนิล แก้วด้วง และคณะ
J Hematol Transfus Med Vol. 27 No. 2 April-June 2017


 


  

    
   

   
    
    

   
≥    

    
   

    
   

≤   
    

   
    
    

   
    

   
    

  
  
≤  
≥  

≤  
≤  


วารสารโลหิตวิทยาและเวชศาสตรบริการโลหิต
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
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 




   












 

 

  






 
 p value




    
    
    
    
    
    
    

ประไพนิล แก้วด้วง และคณะ
J Hematol Transfus Med Vol. 27 No. 2 April-June 2017


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









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 

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 
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 
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

 
 

 
    



วารสารโลหิตวิทยาและเวชศาสตรบริการโลหิต
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 




     

  

 
   
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

 
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 ä
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