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The Effect Of Chlorella Supplementation On Exercise Performance And Inflammation-related Blood Cells After Dehydration.: 3265 Board #170 June 2 2

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... At the end of the study, there was a significant decrease in TNF-α levels compared to the placebo group [23]. In another study, Lin et al. stated that chlorella supplement improves anaerobic exercise capacity and also reduces post-dehydration muscle inflammation after exercise training [24]. Farther more, Ebrahimi et al. observed weight-loss in groups that took this supplement [25]. ...
... Horii et al. investigated glycolytic and oxidative capacities in rats and showed that high-intensity exercise along with using chlorella vulgaris improves glycolytic and oxidative capacities [27]. Lin et al. stated that Chlorella vulgaris supplement anaerobic exercise capacity and also reduces muscle inflammation following exercise [24]. Lee [22]. ...
... Reducing fat and improving insulin metabolism following exercise, along with supplementation with chlorella supplements, may be involved in lowering levels of inflammatory cytokines such as IL-6 [19]. Researchers believe that exercise, especially intense exercise causes autohypnosis or damage to muscle and plays an effective role in release of various substances such as intracellular proteins and cytokines [24], that IL-6 is one of the pro-and anti-inflammatory cytokines that has controlling effect on T-regulatory cells and affects the function of other inflammatory cells. Adipose tissue high levels of IL-6 so high production and secretion of IL-6 from adipose tissue causes negative regulation of metabolism and deficiency in muscle glycogen synthesis in overweight people, which ultimately plays an important role in increasing insulin resistance in body; thus, losing weight and fat following exercise will be associated with a decrease in IL-6 and consequently insulin resistance, overweight people generally have higher plasma concentrations of inflammatory markers (parameters) compared to normal people. ...
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PurposeOverweight can lead to the down-regulation of insulin sensitivity and cytokine profile. In this regard, non-pharmacological interventions such as exercise and supplementation are recommended. Therefore, the aim of this study was to investigate the synergistic effect of Chlorella vulgaris supplementation with acute eccentric exercise on serum levels of interleukin-6 and insulin resistance in overweight men.Methods Thirty subjects (aged 22.8 ± 2.1 years, BMI 27.1 ± 9.6 kg/m2) were randomly divided into three equal groups: exercise [just perform acute eccentric exercise test (AEE)], Chlorella vulgaris (for 7 days and then AEE), placebo (for 7 days and then AEE). Blood sampling was performed in 4 stages: day 1 (before supplementation) and day 7 (after supplementation), after AEE and 24 h after AEE. Subjects of the supplement group received Chlorella vulgaris supplement (300 mg) four times daily for 1 week, and the placebo group consumed similar dextrose tablets. Exercise groups just perform AEE. AEE test included a 20-min treadmill run at a speed of 9 km/h with a negative 10% slope. Serum levels of IL-6, insulin, and glucose were measured by Elisa kit. Also, the hip circumference and knee range of motion (ROM) was measured at four stages.ResultsAt the end of the study, there was a significant decrease in IL-6 levels in the Chlorella vulgaris group compared to the other two groups at 24 h after AEE test (P < 0.01). There was also a significant decrease in insulin resistance levels in the supplement group compared to the other two groups at 24 h after AEE test (P < 0.02). Also, the knee ROM decreased significantly in all three groups (P < 0.05).Conclusion Chlorella vulgaris with acute eccentric exercise can have a more modulating effect on serum IL-6, insulin resistance and other characteristics in overweight men compared to acute eccentric exercise without chlorella.
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Introduction Considering the role of Chlorella Vulgaris supplementation in increasing the performance and improving body inflammation status, the purpose of this study was to investigate the effect of six weeks of HIIT program and Chlorella Vulgaris supplementation on the IL-6 and insulin resistance in overweight men. Materials and Methods Thirty subjects in this study (22.8 ± 1.2 yrs.; 27.1 ± 9.66 BMI) were randomly assigned into three groups (10 N each group), Before and 48 hours after the end of 6 weeks of HIIT training, blood samples were taken from subjects and used for interleukin-6, insulin, and glucose serum levels measurements. The participants' training program included 6 weeks of intensive HIIT program with 90% Vo2max intensity. Subjects of the supplement group received chlorella Vulgaris supplementation (300 mg) for six weeks. The data were analyzed by repeated measure ANOVA and Significance level (p <0.05) was used for all data analyses. Results The results showed that Chlorella Vulgaris supplemented with HIIT exercises significantly decreased IL-6 compared to other groups (P=0.041). The insulin resistance index showed significant changes when comparing the three groups (P=0.011). Body composition results showed a decrease in body fat (P=0.009) and an increase in aerobic fitness (P=0.016) of subjects in the supplement+HIIT group compared to other groups. Conclusion Chlorella Vulgaris consumption with six weeks of HIIT program reduced IL-6 and improve insulin resistance in overweight men. Keywords Exercise, Insulin Resistance, Overweight, Inflammation
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