OBJECTIVE: To systematically evaluate the quality of Spatholobus suberectus. METHODS: The contents of 6 marker compounds in 23 samples of Spatholobus suberectus collected from different areas and markets were analyzed by HPLC method. Some physical and chemical tests( EtOH extract, total ash, acid-insoluble ash, H2O) were used to investigate their quality. RESULTS: There were significant ... [Show full abstract] differences among 23 batches of crude drug material of Spatholobus suberectus in contents of 6 index compounds as well as some physical and chemical parameters. The contents of epicatechin and isoliquiritigenin were highest in 6 index compounds. CONCLUSION: The study provided reference in order to systematically evaluate the quality of Spatholobus suberectus.