The quality of life is affected by many factors, which can be combined according to the similar attributes into some dimensions. A major impact on quality of life has a feeling of security. The quality of life is directly related to the development of regions that can be examined through subjective and objective indicators as well as the security situation. The paper is going to deal with selected socio-economic indicators of regional development that directly affect the safety of citizens, and therefore their quality of life. There will be evaluated primary socio-economic indicators of regional development such as regional gross domestic product, the level of economic activity, the rate of regional employment and unemployment, the average regional wages. Trough comparison of the above indicators can be seen if the qualities of life in Slovak regions have been positive and what is the position of regions in terms of development. Keywords: Quality of life, regional development, regional disparities, socio-economic indicators;
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