Introduction to a medical science and health paradigm change

Abstract

In the last forty years there has been a great change of medical science through the progress of neurobiology, the birth of quantum biology, the development of epigenetics, the change of physiology with the concept of “Allostasis instead of “Homeostasis”, the opening of new interactionist investigation fields like Psycho-neuro-endocrine-immunology and the consequent formulation of the Theory of the relativity of biological reactions. At the same time there has been the integration of Medicine with human sciences such as cognitive psychology, psychoanalysis, counseling allowing to discovery a teleology of human nature. The change can be considered an indeterminist revolution of medical science, similar to the shift to quantum physics, from the Newtonian determinism and mechanism happened in Physics at the beginning of the last century. The epistemological change of Medicine is based on an irrefutable interactionism of three orders of variables belonging to subjectivity, biology and environment and to a natural tendency to give an objective meaning to life, giving importance to quality of life and lifestyle for the health construction. The concept of health appears related before its expression in the human biology, in a symbolic work made by the person addressed to interpret the quality of possibilities perceived in the external and internal experience in analogy to the interpretation work of biological information made by the membrane cell for answering to the adaptation requests. Disease, suffering, physicians are a personal experience of life that call for a meaning and a question for an answer that can’t be explained by empirical variables but that interact with these. The health definition introduced to WHO in 2011 in such a way appears:” The choice of the best possibilities for the best being a human person”. There is a true risk that Medicine could be developed on schizophrenic epistemology dissociated from the progress of the basic sciences. The Milan Conference held on 13-14-15 October 2017 wants to formalize a determinant shift for Clinics, clinical investigation, medical education and public health policy.

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Medical Science and Health Paradigm Change
13-14-15 October 2017
Milan, Regione Lombardia,Italy, Ospedale Maggiore – Ca Granda
©Copyright Giuseppe R.Brera 2016-2017
Introduction to a Health and Medical Science Paradigm Change
Giuseppe R.Brera*
Socrates…… Well then, could we ever know what an art makes the man himself better, if we were ignorant of
what we are ourselves ?
Alcibiades: Impossible ! (Plato)
There is an urgent necessity to promote consensus in the scientific community for formalizing the
deep epistemological change happened in health sciences in the last forty years through the change of the
paradigm of neurobiology,
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the birth of quantum biology,
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the development of epigenetics,
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the
change of physiology with the concept of “Allostasis”,
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the opening of new interactionist investigation
fields like Psycho-neuro-endocrine-immunology
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and the Affect science.
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At the same time there has
been the integration of Medicine with human sciences such as cognitive psychology , psychoanalysis,
counseling. This change can be considered an indeterminist revolution of medical science, similar to the
shift to quantum physics, from the Newtonian determinism and mechanism created by the supremacy of
positivism (Claude Bernard) and the Descartes dualism and has been theorized by the Relativity Theory of
Biological Reaction,
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built in 1996 in the light of the fall of the Selye’s mechanic stress-answer biological
linear causality and the neuro-endocrinological investigation
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.The progress in the basic sciences and in
medicine epistemology, introduced two main concepts: the interactions between the three orders of
variables belonging to subjectivity, biology, and environmental physical - relational stimuli
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and the
human nature teleology, the making meaning, that means the natural tendency to truth, love and beauty,
evidenced by the human sciences. The only human symbolic work of interpreting information creates an
analogy with the biological interpretation work made by the cell membrane for answering to the
adaptation requests. Health appears relative and related to human individual symbolic answers, impossible
to animals, which interpret internal and external possibilities received, correspondent to biological
information to the biological organism through biochemical and quantum signals, learnt and/or memorized
sent by the person, who pilots the interaction between the three worlds of variables naturally addressed to
look a unitary meaning: the being a human person, according to a mysterious quest for a true meaning of
life. Coping with a disease, suffering, physicians are a personal experience of life belonging to existence,
that call for a right or wrong meaning that can’t be explained by empirical variables that interact with
these, building in such way a relativity to this interpretation and to the consequent coping and behavior
possibilities and quality.
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Health appears based on a semantic hologram. The epistemological change
of medical science has brought to the birth of Person Centered Medicine paradigm (1998)
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, the
derived Person Centered Medicine Clinical method
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and the Person Centered Health concept
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that in
2011 I proposed to WHO
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as “Person Centered Health”, re-assessed like “The choice of the best

Medical Science and Health Paradigm Change
13-14-15 October 2017
Milan, Regione Lombardia,Italy, Ospedale Maggiore – Ca Granda
©Copyright Giuseppe R.Brera 2016-2017
possibilities for being the best human person” , call the physicians to be “Person Centered Health
anthropologists” and to re-conceive medicine like an anthropology of the human nature. Clinicians, to
date, should be able to conceive their work like a “Maieutics” of the person’s individual nature, creating for
the patient possibilities for interpreting a clinical event like an existential one, reformulating the diagnosis
as “Person centered”, looking interactions among the three worlds of variables and the disease also like a
possibility for discovering a hidden meaning and to improve quality of life in a social and environmental
context, giving the right meaning to the perceived possibilities for it. The person in this way cannot be
reduced to an abstract bio-technological diagnosis, only necessary in a biological survival emergency not
only based on a stimulus-answer linear causality diagnosis and therapy, but this approach is a risk factor for
health if excludes the right multifactorial and teleological interactionism, to date right epistemological
reality of a person centered health and medical science , to date, in the light of the medical science
progress, obligatory in primary care, prevention, research and pre-post degree medical education. The
95% of pathologies from non-communicable diseases come from a lifestyle
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built on the true or false
quality of being a person depending on the right or wrong quality of the interpretation of the perceived
possibilities and from right or wrong choices for the wellbeing.
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Communicable diseases are epidemic
where there aren’t health policies addressed to create possibilities for health, changing environmental and
social conditions that create more vulnerability to infections and transmission of diseases, taking also in
account that peace is a necessary protective factor for health. To date we know that we cannot separate
existence from science and both from health and Medical science and the construction of a right society
where health and life are possibilities for all the human beings !
On 13-14-15 October in Milan, Lombardia Region, Italy the Conference “ Medical Science and
Health Paradigm Change” has been held , addressed to create a scientific consensus, discussion and further
confirmation of theories through scientific contributions about this revolutionary change for a new health
concept, impeding a schizophrenic evolution of Medicine, dissociated from basic sciences with a necessary
shift for building right policies oriented to the person’s freedom and human rights.
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©Copyright Giuseppe R.Brera 2016-2017
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