Every scientific or intellectual movement rests on central premises and assumptions that shape its philosophy. The purpose of this study is to review a brief account of the main philosophical bases of grey systems theory (GST) and the paradigm governing its principles. So, the recent studies on the philosophical foundations of GST have been reviewed and tried to pay attention to some key ambiguities in the previous studies and give more and clearer explanations in this paper. Also, this paper tries to fill the gap among the previous studies and to provide a purposeful connection between them by expressing two key concepts: complete information and imbalance knowledge. Primarily, the study addresses the theoretical foundations of uncertainty and the concept of greyness. Next, it focuses on the notion of “complete information” and challenges to it. Then, it reviews such processes as perception, cognition, and understanding, as well as their dynamic nature. It explains how knowledge is produced through understanding and interpreting information/data and the dynamics governing the whole process. Also, the study describes any dataset, no matter how large it may be, will remain incomplete, imperfect, and grey, so humans only rely on incomplete datasets to interpret the world. As such, information and knowledge are always grey and uncertain because they are basically contingent on subjective understandings and interpretations and imperfect inputs and data. Finally, as a key development, this study also demonstrates that human grey knowledge remains imbalanced across different disciplines and spheres. In the end, a brief overview of the philosophical paradigm of GST is also provided. GST is depicted as an anti-realistic, anti-positivistic, and non-deterministic approach, which is inherently pluralistic and ideographic. According to GST principles, dynamicity and change are essential parts of human narratives of the world and systems, and human knowledge is constantly reproduced through collecting new information. As a result, knowledge, theories, narratives, and scientific laws dynamically change. Given this premise, one could argue that GST is considerably compatible with the postulates of post-modern thinking.