: This paper aims at translating the Gratitude Questionnaire (GQ-6) into Italian and at investigating its validity and reliability in this context. In a web-based survey, 204 adult participants ( M age = 28.96; SD = 10.27) completed the Italian version of the GQ-6, as well as subjective happiness, life satisfaction, loneliness, and social desirability questionnaires. Exploratory and confirmatory factor analyses supported a one-factor solution explaining 46.16% of the variance of the original items and an acceptable Cronbach’s alpha equal to .745. The Italian version of the GQ-6 was, as expected, positively correlated with subjective happiness, life satisfaction and social desirability and was negatively associated with loneliness, which supported its construct validity. The Italian version of the GQ-6 also showed a discriminant validity relative to other positive affects and a good criterion validity in differentiating both believers and non-believers and high and low envious people.