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Abstract

Chaperone association with muscle and HLH-1 binding. (A) Flowchart outlining the filtering analyses of the chaperone list. (B) Summarized data from bioinformatics analyses. (XLSX)
Flowchart outlining the filtering analyses of the chaperone list
(A) Defenition of the Muscle associated group
(B) Filtering the full chaperone list by HLH-1 occupancy sites and muscle associattion
Filtering the full chaperone list by HLH-1 occupancy sites and muscle associattion
Chaperone (A) HLH-1 occupancy (B) Muscle- enriched
Genes Motif
Group 1
unc-45 +++++++
unc-23 + + + +
cct-7 + + + + +
hsp-12.1 + + + +
hsp-25 + + + +
sgt-1 ++++++
daf-21 ++++ +
cct-1 + + + + +
cct-2 ++++ +
dnj-24 + +
ZC395.10 + +
cct-8 + + +
dnj-13 + +
hip-1 + + +
hsp-12.2 + + + +
C34B2.5 + + + +
cct-4 + + +
dnj-18 + + + +
hsp-1 +
hsp-12.3 + + +
hsp-43 + +
sti-1 + +
Y55F3BR.6 +++++
C34C12.8 + + + +
cct-5 +++
dnj-3 + + +
sip-1 + + +
Y22D7AL.10 + + +
cct-3 +
dnj-12 + + +
dnj-14 + + +
dnj-28 + +
hsp-110 + + +
hsp-16.2 + +
hsp-16.49 + +
hsp-3 + + +
hsp-4 + + +
rme-8 + + +
T24H7.2 + + +
Group 2
dnj-16 +++
C17G10.2 +++
dnj-1 + +
dnj-15 + +
Lie et al.,
2010 Kuntz et al., 2012 Fox et al.,
2007
Kuntz et al.,
2012
Roy et al.,
2002
dnj-9 + + +
enpl-1 + + +
bag-1 + +
cdc-37 + +
dnj-10 + +
dnj-20 + +
dnj-25 + +
dnj-26 + +
dnj-27 +
dnj-29 +
F44E5.4 + +
F54F2.9 +
hsp-12.6 + +
hsp-16.48 +
hsp-6 +
hsp-60 +
hsp-75 + +
ZK1128.7 +
ZK370.8 + +
Group 3
C01G10.8 +
cct-6 + + +
C33H5.8 + + +
dnj-19 + +
chn-1
D1054.3 +
dnj-7 + +
dnj-8 + +
F11F1.1 + +
hsp-16.1 + +
hsp-16.41 + +
pph-5 + +
T14G8.3 + +
Y39C12A.9 + +
Group 4
C17G10.10 +
C56C10.10 +
dnj-11 +
dnj-17 +
dnj-2 +
dnj-21 +
dnj-22 +
dnj-23 +
dnj-30
dnj-4 +
dnj-5 +
F08H9.3 +
F08H9.4 +
F44E5.5 +
fkb-6 +
hsp-16.11 +
hsp-17 +
hsp-70 +
K07F5.16
stc-1 +
Y22D7AL.9
(C) Muscle-required
Folding Localization
Group 1
+ + +
+ + +
+
+ +
+ +
+ +
+
+
+ +
+ +
+
+ +
+
+
+
+ +
+
+ +
+ +
+
+
Group 2
Myopathies
or Paralysis
Group 3
+ +
+
+
Group 4

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