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Phenomenology of Misophonia: Initial Physical and Emotional Responses

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  • Misophonia Treatment Institute

Abstract and Figures

Objective: Misophonia is typically characterized as an extreme emotional response to auditory and visual stimuli. In several case studies, physical responses have also been reported. This study sought to determine whether adults with misophonia experience physical responses in addition to emotional responses in the presence of triggering stimuli. Method: Twenty-seven adults with misophonia were interviewed via teleconferencing. Participants self-reported the presence of physical and emotional responses to triggers (i.e., two auditory and one visual). Results: All participants reported physical responses to at least one of their triggers. There was great variation in the region of the physical responses across participants. Approximately half of the sample reported region consistency across triggers. Likewise, all participants reported emotional responses to at least one of their triggers. Conclusion: These results suggest including an immediate physical response as part of the conceptualization of misophonia. They also support classical conditioning of a physical response as a possible contributing mechanism for the etiology of misophonia.
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American Journal of Psychology
Winter 2017, Vol. 130, No. 4 pp. 431–438 • ©2017 by the Board of Trustees of the University of Illinois
Phenomenology of Misophonia:
Initial Physical and Emotional Responses
THOMAS H. DOZIER
Misophonia Treatment Institute
KATE L. MORRISON
Utah State University
Misophonia is typically characterized as an extreme emotional response to auditory and visual
stimuli. In several case studies, physical responses have also been reported. This study sought to
determine whether adults with misophonia experience physical responses in addition to emo-
tional responses in the presence of triggering stimuli. Twenty- seven adults with misophonia
were interviewed via teleconferencing. Participants self- reported the presence of physical and
emotional responses to triggers (i.e., two auditory and one visual). All participants reported
physical responses to at least 1 of their triggers. There was great variation in the region of
the physical responses across participants. Approximately half of the sample reported region
consistency across triggers. Likewise, all participants reported emotional responses to at least 1
of their triggers. These results suggest including an immediate physical response as part of the
conceptualization of misophonia. They also support classical conditioning of a physical response
as a possible contributing mechanism for the etiology of misophonia.
KEYWORDS: misophonia, classical conditioning, reflex, selective sound sensitivity syndrome,
neurodevelopmental disorders, Pavlovian conditioning, sound sensitivity
other sensory modalities (e.g., tactile, olfactory, low-
frequency vibration; Dozier, 2015d).
The etiology of misophonia is unknown, with
onset occurring predominantly in childhood or the
early teens (Claiborn, Dozier, Hart, & Jaehoon, 2017;
Edelstein et al., 2015; Schröder et al., 2013; Wu et
al., 2014). Onset also occurs in adulthood, but at
much lower rates (Claiborn et al., 2017). It has been
hypothesized that misophonia may originate from a
defective structure in the inferior part of the temporal
lobe (Møller, 2011), as part of a general hyperreactivity
syndrome (Schröder et al., 2013), or through classi-
Misophonia is commonly characterized as an extreme
emotional response of anger or disgust to common-
ly occurring innocuous auditory and visual stimuli
(Edelstein, Brang, Rouw, & Ramachandran, 2013;
Jastrebo & Jastrebo, 2014; Schröder, Vulink, &
Denys, 2013; Wu, Lewin, Murphy, & Storch, 2014).
Misophonia is a newly identied condition and may
be surprisingly common. One study of psychology
undergraduate students reported that 19.9% had
clinically significant misophonia symptoms (Wu
et al., 2014). Stimuli that cause such a response are
commonly referred to as triggers and can include
AJP 130_4 text.indd 431 8/17/17 7:01 PM
432  •  DOZIER AND MORRISON
cal conditioning (Dozier, 2015b, 2015c; Jastrebo &
Jastrebo, 2002, 2014; Schröder et al., 2013).
Several studies have reported physiological
arousal in response to trigger stimuli, including in-
creased skin conductance, heart rate, blood pressure,
and a feeling of pressure in the body, as an accompa-
nying stress response to misophonic triggers (Clai-
born et al., 2017; Edelstein et al., 2013; Jastrebo &
Jastrebo, 2014; Schröder et al., 2013). Edelstein et al.
(2013) empirically validated the autonomic arousal by
measuring the skin conductance response (SCR) to
prolonged exposure to misophonic auditory stimuli.
SCR began rising 2 s after onset of the trigger stimulus
and continued to rise for the duration of the stimulus.
The stress response is illustrated in Figure 1a, which
displays the prevalent conception of misophonia.
Several case studies and one survey have reported
a physical response, typically a skeletal muscle con-
traction (e.g., inch, various muscle contractions), to
trigger stimuli (Claiborn et al., 2017; Dozier, 2015a,
2015b, 2015c; Pearson, 2015). Dozier (2015b, 2015c,
2015d) proposed an alternative model of the miso-
phonic response that includes this physical response
elicited by the trigger stimulus (Figure 1b). In the pro-
posed model, the misophonic emotional response is
elicited primarily by the sensation of the initial physi-
cal response. The dashed line in Figure 1b shows
a secondary path whereby the trigger stimulus may
directly contribute to the strength of the emotional
response. The proposed response paths are similar
to the James–Lange and Cannon–Bard theories of
emotion, which discuss the order and processing
of physiological and emotional responses to stimuli
(Cannon, 1987). Though similar, the model put forth
by Dozier (2015b, 2015c, 2015d) includes a sometimes
visible muscle inch or ticlike movement beyond
the emotional and physiological responses in those
models. Dozier’s model proposes that misophonia
is an aversive physical and emotional reex disor-
der. Moreover, Dozier (2015b) posits that misophonia
includes a classically conditioned aversive physical
response to selective stimuli, which does not extin-
guish with in vivo exposure.
Aversive stimuli have been shown to evoke anger
in humans (Berkowitz, 1983; Berkowitz, Cochran, &
Embree, 1981). Neuroimaging studies have shown
increased activity in the limbic system of humans
in response to aversive gustatory stimuli (Zald, Lee,
Fluegel, & Pardo, 1998), aversive odorants (Zald &
Pardo, 1997), and aversive auditory stimuli (Zald &
Pardo, 2002). The physical response to misophonic
trigger stimuli has been reported as severe by some
people and very mild by others (Dozier, 2015b). Even
in cases where the physical response is weak, it is
intrusive and may therefore be aversive.
The existence of an initial physical response is
an important consideration in elucidating misopho-
nia, but the emotional response to real- life trigger
stimuli may mask the perception of that response
(Dozier, 2015c, 2015d). This study sought to deter-
mine whether physical sensations could be identied
when misophonic people were presented with weak
trigger stimuli. Providing evidence of an initial physi-
cal response in a controlled study may lead to in-
creased awareness and recognition of this previously
reported characteristic of the misophonic response.
It may also identify a widespread example where a
physical response contributes to extreme emotional
responses.
FIGURE 1. (a) Prevalent conception of misophonia emotional and physical
response to trigger stimuli. The trigger stimulus elicits the misophonic extreme
emotions and the accompanying stress response. (b) Alternative conception of
misophonia response chain, including the initial physical response. The trigger
stimulus elicits a physical response, and the sensation of the physical response
elicits the extreme emotions and accompanying stress response
AJP 130_4 text.indd 432 8/17/17 7:01 PM
MISOPhONIA AND RESPONSE • 433
EXPERIMENT
METHOD
Participants
Invitations were sent to 194 people (31 men and 163
women) randomly selected from those who, as part
of an online survey of adults with misophonia symp-
toms, indicated a willingness to participate in further
study phases. The high rate of female participation
in the survey is consistent with other self- selection
misophonia studies (Cash, 2015; Wu et al., 2014),
even though those studies found no signicant gen-
der dierence for prevalence. Eligibility required that
participants be 18 years of age or older and report
at least two misophonic trigger stimuli. Of the 194
contacted, 27 people returned the informed consent
form and completed the study interview (7 men and
20 women, mean age = 38.3 years; range = 18–63
years). The responses of one person were excluded
from analysis because responses intermixed thoughts,
emotions, and physical sensations for both the physi-
cal and emotional questions. Based on the Amster-
dam Misophonia Scale (range 0–24; Schröder et al.,
2013), which was administered as part of a previous
study, the misophonia severity ratings of participants
ranged from subclinical to extreme, with the mean
between moderate and severe (M = 14.38, SD = 3.81,
range = 4–21).
Procedure
This study was approved by the Sterling Institutional
Review Board. After being invited to participate in
the interview, participants returned the completed
informed consent, a form that designated the types
of triggers that would be used in the interview and, if
necessary, any recording of those triggers via e- mail.
The trigger form requested identification of one
visual and two auditory triggers. Each trigger was
designated as either “trigger made by investigator”
or “recording will be provided.” At that time, a one-
time appointment was scheduled to meet via VSee
(a Health Insurance Portability and Accountability
Act–compliant telehealth videoconferencing plat-
form). Interviews were conducted by both authors.
Before the interview, the interviewer veried that
recorded trigger les played properly and prepared
the materials to produce triggers (e.g., chips, gum,
video of kissing). The interviews lasted approxi-
mately 20–30 min. At the start of the interview, the
informed consent was reviewed for participant clari-
cation. Once assured it was fully understood, the
interviewer read the following script:
The purpose of this meeting is to help you
identify the physical sensations that you have
when you are triggered. In real life, the emo-
tions are so overpowering that almost no one
can accurately identify the physical sensations
that occur immediately after a trigger. The
research on reexes indicates that the smaller
a trigger stimulus, the smaller the response. I
will attempt to make the trigger so tiny that it
does not cause any reex response. Then I will
slowly increase the trigger until you start to be
triggered. At that point, I will ask you to report
the strength of the trigger (on a scale of 0–10),
any physical sensation you have, and any emo-
tions you experience.
Each trigger was tested several times. For each
auditory trigger test, participants were asked to close
their eyes and relax their muscles. The interviewer
produced a very low- level trigger (i.e., low volume
and short duration), and the participant was asked
whether it triggered them. The trigger was slowly
increased until the participant was triggered. The
participant then reported the strength of the trig-
ger, physical sensations, and emotions experienced.
The interviewer prompted for clarication of the
responses when needed. For subsequent tests of
the same trigger, the interviewer attempted to ad-
just the trigger to have a “trigger strength” of 2 to
4, as reported by the participant. This procedure
was repeated several times until a consistent physi-
cal response was reported (dened as two matching
consecutive responses) or a maximum of 10 tests were
completed. The procedure for visual triggers was the
same as for auditory triggers, except participants were
asked to relax their muscles with their eyes open and
close their eyes as soon as they were triggered. The
researcher produced the trigger, attempting to start
with a nontriggering stimulus and slowly increase
the trigger strength until participants closed their
eyes. The strength of the visual trigger was adjusted
by the size of the image on the screen and topology.
For example, if the trigger was open mouth chewing,
the interviewer started chewing with a closed mouth
and progressively increased the separation of the lips
until the participant closed his or her eyes. With this
method, the trigger strength rating was maintained
AJP 130_4 text.indd 433 8/17/17 7:01 PM
434  •  DOZIER AND MORRISON
in the same range for visual and auditory triggers.
The interviewer’s microphone was muted during the
test for a visual trigger to ensure that the misophonic
response was elicited solely by the visual image. The
two auditory and one visual triggers were tested using
this format, with the exception of two participants
who had only auditory triggers. Participant responses
were recorded on a data collection form by the re-
searcher and later entered into a data le.
Interviewer Interrater Reliability
To ensure interviewer interrater reliability, 6 of the
27 interviews (22%) were observed by the other au-
thor. The observer was blocked visually and audibly
from both the participant and interviewer after mak-
ing the participant aware of his or her presence. The
observer completed the same data collection form
and entered the data into a separate data le for later
comparisons. Interrater agreement was calculated
for the physical and emotional response data. The
percentage agreement was calculated as the number
of responses that completely matched, divided by to-
tal responses. Interrater agreement was 91.1%, which
suggests high agreement between the observer and
interviewer.
Data Analysis Techniques
The physical response was determined according
to three rules. First, if two consecutive responses
were identical, those responses were reported (57 of
76 tests, 75.0%). Second, if a set of responses did
not meet the rst rule but were reported in three
consecutive tests, and each response was reported
at least twice, then all the responses were reported
(9 of 76 tests, 11.8%). Third, if the rst and second
rules were not met, responses that occurred two or
more times were reported, and any further responses
were reported as various (10 of 76 tests, 13.2%). All
emotional responses reported were included in the
data summary. The second author reviewed 19.2%
(randomly selected) of the total participant responses
to ensure accuracy of the data summary. The data
summary interrater agreement was 100%.
RESULTS
Physical Responses
Each participant was tested with two dierent audi-
tory triggers and one visual trigger, except for the two
participants who did not have any visual misophonic
triggers. The physical and emotional responses for all
triggers tested are shown in the supplemental table.
The physical responses for each person are summa-
rized in Table 1. Responses are grouped into major
categories. For example, responses of upper arms,
forearms, hands, and ngers are grouped into arms
and hands. A response of trapezius (e.g., participant
reporting shoulders at the neck or pointing to this
location) is included in the shoulders and neck groups.
Three participants (11.5%) had one or two trig-
gers wherein they consistently reported no physical
response. One participant (3.8%) reported a physi-
cal response but intermittently reported no physical
response from two triggers. The responses to many
TAbLE 1. Summary of Physical Responses to Trigger Stimuli
Physical
response
Number of
participants
(
n
= 26)
% of
Participants
Number
of trigger
tests
(
n
= 76)
% of
Trigger
tests
Shoulders 13 50.0% 26 34.2%
Arms and
hands
11 42.3% 24 31.6%
Neck 9 34.6% 17 22.4%
Chest 5 19.2% 8 10.5%
Back 5 19.2% 8 10.5%
Abdomen 4 15.4% 8 10.5%
Jaw 3 11.5% 5 6.6%
Thighs 2 7.7% 4 5.3%
General
tensing
2 7.7% 3 3.9%
Sexual
(e.g., clitoral,
vaginal)
2 7.7% 2 2.6%
Warmth 2 7.7% 5 6.6%
Toes 2 7.7% 3 3.9%
Stomach or
nausea
2 7.7% 2 2.6%
Breath 2 7.7% 2 2.6%
Torso 2 7.7% 3 3.9%
Head 2 7.7% 2 2.6%
Face 1 3.8% 1 1.3%
Numb
sensation
1 3.8% 1 1.3%
Various 8 30.8% 10 13.2%
None 4 15.4% 7 9.2%
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MISOPhONIA AND RESPONSE • 435
of the triggers included more than one muscle group;
therefore, the sum of the percentages in Table 1 is
greater than 100%. Table 2 shows the number of par-
ticipants with same, similar, dierent, and no physical
responses. All participants (100%) reported a physical
response to at least one of their tested triggers. Table
3 provides examples of the consistency of responses
to dierent trigger stimuli.
It was dicult for some participants to determine
the location of the response. For example, one par-
ticipant reported feeling panic and fear in the rst
instance of the trigger and a physical sensation in the
gut and shoulders in the second instance. After sev-
eral more exposures to weak triggers, the participant
consistently reported a slight tensing of the abdomen
as the physical response to triggers. Therefore, in
many cases the exact location of the physical response
should not be considered reliable (e.g., whether the
response was in the neck versus the neck, shoulders,
and chest).
Emotional Responses
Emotional responses were recorded for each trigger
test. Actual responses from each trigger tested are
listed in the supplemental table. Four participants
(15.4%) had one or two triggers wherein they con-
sistently reported no emotional response. The only
emotion that one of these participants reported in all
the individual trigger tests was that he “wanted them
to go away.” Another four participants (15.4%) report-
ed emotional responses but intermittently reported
no emotional response for one or more triggers. A
summary of the emotional responses to triggers is
shown in Table 4, as a percentage of participants and
of triggers tested. As with the physical responses, the
sum of the percentages is greater than 100% because
multiple emotions were often reported for each trig-
TAbLE 2. Within- Participant Similarities and
Differences of Responses to Triggers
Responses to different
triggers
Number
participants
(
n
= 26) %
Same (all) 6 23.1%
Same or similar (all) 15 57.7%
Same (2 or more) 13 50.0%
Same or similar (2 or more) 19 73.1%
Different (1 or more) 11 42.3%
No response (1 or more) 4 15.4%
Physical response (1 or more) 26 100%
TABLE 3. Examples of Physical Responses Consistency to Triggers
Responses
to different
triggers
Example of physical response of participant
Auditory
trigger 1
Auditory
trigger 2
Visual
trigger
Same (all) Hand clench,
jaw
Hand clench,
jaw
Hand clench,
jaw
Same or similar
(all)
Neck,
shoulders,
upper back,
upper arms
Shoulder,
upper back
Neck,
shoulders,
head tilt to
left
Same (2 or more) Shoulders,
chest
Varied Shoulders,
chest
Same or similar
(2 or more)
Shoulders,
upper arms,
chest
Shoulders,
upper body,
abdomen
Whole arms
Different
(1 or more)
Neck,
shoulders
Chest Neck,
shoulders
No response
(1 or 2)
Arms, hands Arms, hands None
Physical response
(1 or more)
None None Shoulders
TAbLE 4. Summary of Emotional Responses to Trigger Stimuli
Emotional
response
Number of
participants
(
n
= 26)
% of
Participants
Number
of trigger
tests
(
n
= 76)
% of
Trigger
tests
Anger 24 92.3% 57 75.0%
Anxiety 24 92.3% 32 42.1%
Desire for
escape
14 53.8% 23 30.3%
Disgust 12 46.2% 17 22.4%
Fear 6 23.1% 9 11.8%
Sadness 4 15.4% 5 6.6%
Other 9 34.6% 9 11.8%
None 8 30.8% 15 19.7%
AJP 130_4 text.indd 435 8/17/17 7:01 PM
436  •  DOZIER AND MORRISON
ger. The categories of emotion are aggregations of
similar emotions. For example, aggravation, irritation,
annoyance, frustration, anger, and rage are combined
into the anger category. All participants (100%) re-
ported an emotional response to at least one of their
tested triggers.
DISCUSSION
Although other studies have reported general physi-
ological arousal in response to strong or prolonged
trigger stimuli including muscle tension (Edelstein et
al., 2013; Schröder et al., 2013; Wu et al., 2014), this is
the rst research study to report a physical response
to trigger stimuli that often included specic skeletal
muscle contraction and movement. Edelstein et al.
(2013) concluded that their misophonic participants
“reported physical symptoms synonymous with au-
tonomic arousal” (p. 8). In the current study, par-
ticipants reported their perceived physical response
after weak auditory stimuli. Weak stimuli and time
between tests were intended to prevent general
physiological arousal, so that the participants could
be aware of their physical sensations in response to
trigger stimuli. We posit that the reported physical
sensation was an immediate elicited response from
the stimulus and not autonomic arousal, as reported
in other studies. Although there were some trigger
tests in this study wherein the participant reported
experiencing no physical response, most participants
reported a physical response to each trigger stimulus,
and every participant reported a physical response to
at least one of their tested triggers.
The physical responses were highly varied, with
reports of skeletal muscle responses predominating.
Some participants reported a response in a single
area, such as hands or abdomen, and many reported
multiple muscles (e.g., hands and shoulders). The
non–skeletal muscle responses included a feeling of
warmth, stomach contraction, nausea, clitoral sensa-
tion, and contraction of the vagina. More than half
of participants reported the same or similar physical
response for all triggers tested. Most reported the
same or similar physical response for two or more
triggers, and 42% of participants had distinctly dier-
ent physical responses to at least one of their triggers.
The most important nding is that the misophonic
response to triggers includes a physical response that
may be unique to each participant. Thus, the recom-
mendation would not be to categorize misophonia by
specic physical responses but rather incorporate
the general presence of these automatic physical re-
sponses into the understanding of this phenomenon.
Anger (and lesser precursors), anxiety, disgust,
and avoidance were the most common emotions re-
ported by participants in response to a single weak
instance of a trigger, with anger being the dominant
emotion. This was consistent with emotional reports
in other studies in response to typical trigger stimuli
(Edelstein et al., 2013; Wu et al., 2014). However, the
reported fear response was novel because it is gener-
ally not reported in misophonia studies (Edelstein et
al., 2013; Schröder et al., 2013; Wu et al., 2014).
Weak trigger stimuli were used in this study to
limit the emotional responses and allow percep-
tion of the physical response. The severity of the
responses reported by the participant appeared to
be directly related to the volume and duration of the
trigger stimulus, and these parameters were varied
based on the participant rating of severity. The mild
emotional responses (e.g., irritation, frustration, mild
anger, mild disgust) were probably a function of the
weak trigger stimuli. It may be more appropriate to
say that the weak trigger stimuli limited the physical
and emotional responses, because the strength of a
conditioned physical response is related to condi-
tioned stimulus intensity (Kessen, 1953). It is posited
that strong trigger stimuli, especially those in real-
life situations, would produce stronger physical and
emotional responses. About a third of participants
(30.8%) had instances where they did not experience
an emotional response, and half as many (15.4%) had
instances where they did not experience a physical
response. The trigger stimuli were intentionally weak.
Each participant had several instances where the au-
ditory stimulus did not elicit a physical or emotional
response (i.e., participant did not have a misophonic
response to the stimulus). It seems plausible that a
physical and an emotional response will almost al-
ways be elicited by stronger, real- life trigger stimuli.
The occasional lack of emotional response should
not alter the conceptualization of misophonia as a
condition in which innocuous stimuli elicit or evoke
extreme emotional responses.
The variation in physical responses of partici-
pants supports an individual learning history to
AJP 130_4 text.indd 436 8/17/17 7:01 PM
MISOPhONIA AND RESPONSE • 437
account for the variety of responses. Classical con-
ditioning is a possible mechanism as part of the etiol-
ogy of misophonia, in which each person develops
unique physical responses to repeating stimuli in
their environment. Classical conditioning is typically
conceptualized as an association between a condi-
tioned stimulus (CS) and an unconditioned stimulus
(US), and when the intermittent temporal relation-
ship between the CS and US stimuli is eliminated, the
response extinguishes. However, with misophonia
there is no identiable US for conditioning the miso-
phonic stimulus response, and the response generally
does not extinguish (Dozier, 2015b). Donahoe and
Vegas (2004) reported that conditioning occurred
based on the temporal pairing of a neutral stimulus
(NS) and an unconditioned response. Dozier (2015b)
provides case study examples of people whose condi-
tioning may have occurred with the pairing of an NS
(e.g., chewing sound) and an unconscious behavior.
Schroder et al. (2013) hypothesized that recurrent
conditioning may occur when a child is exposed to
repetitive annoying events related to eating sounds.
Such events could pair an NS (chewing sound) and a
behavioral response (e.g., st clench, shoulder shrug)
unique to the child. This pairing of NS and response
would meet the criteria for conditioning reported by
Donahoe and Vegas (2004). Further basic research
on stimulus–response conditioning may provide
valuable insight and inform future misophonia re-
search. Such basic research may also provide insight
into other potential physical–emotional interactions
such as hating a portable chemotherapy infusion
pump (J. Theobald, personal communication, De-
cember 16, 2015; http://newccboard.colonclub.com/
viewtopic.php?t=11244) or an aversive muscle re-
sponse to phone ringtones that have been paired
with stressful problems (Dozier, 2015b).
Although the nature of this study is insucient to
determine the relationship of the physical and emo-
tional responses, the presence of physical responses
suggests a dierent denition of misophonia than the
prevalent conception of misophonia. Thus, a deni-
tion that includes the presence of physical responses
is recommended based on the findings from this
study: Misophonia is a condition in which a person
experiences an immediate physical response and an
immediate negative emotional response to auditory,
visual, or other modality trigger stimuli.
Limitations
This study has inherent limitations due to its reliance
on self- report of participants. The stimuli were low
intensity and elicited only mildly aversive responses.
The stimuli for each person were dierent based on
their individual misophonic triggers. Many of the
participants had diculty identifying a consistent
physical response, especially at the start of their in-
terviews, and so the repetitions were dierent for
each participant. Continued practice or exposure
to the stimuli could have led to diering responses.
Additionally, there is a lack of accuracy in specifying
the location of the physical response. Although there
may be a lack of precision regarding the location of
the physical response, this does not diminish the fact
that participants experienced a physical response to
exposure of a trigger stimulus.
The method of this study does not provide con-
crete information about timing of the physical or
emotional responses in relation to the trigger stimulus
or each other. Additional testing is needed to pro-
vide empirical data on the temporal relationship of
the stimulus, physical responses, and emotional re-
sponses. The relationship between the stimulus and
physical response might be measured with electromy-
ography, and the temporal relationship between the
stimulus and emotional response might be measured
with brain imaging technology. This study supports
the existence of a distinct physical response but does
not provide information on the priority of the physi-
cal response as hypothesized in Figure 1b. The eects
of self- selection to participate in this study, the high
percentage of female participants, and conducting
the study via webcam are unknown.
Conclusion
This study provides insight into the composition of
misophonia, indicating that misophonia consists of
both involuntary physical and emotional responses
to trigger stimuli. It also documents that auditory
and visual trigger stimuli produce similar physical
responses, demonstrating that misophonia may be
a general sensory condition rather than an auditory
condition. The existence of a physical response has
important implications for understanding the origin,
maintenance, and treatment of misophonia. The re-
sults from this study may suggest conceptualizing
misophonia as an aversive physical and emotional
AJP 130_4 text.indd 437 8/17/17 7:01 PM
438  •  DOZIER AND MORRISON
reex disorder in order to highlight the characteris-
tics of misophonia. Furthermore, this study illustrates
a potentially fundamental psychological process, in
which a physical response may be the maintaining el-
ement of what supercially appears to be a condition
in which typically innocuous stimuli elect extreme
negative emotional responses.
NOTES
Thomas Dozier is a misophonia treatment provider and the
owner of several misophonia apps.
Address correspondence about this article to Thomas
H. Dozier, Misophonia Treatment Institute, 5801 Arlene Way,
Livermore, CA 94550 (e- mail: tom@misophoniatreatment.
com).
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... [10] Furthermore, a study revealed a significant correlation between misophonic reaction intensity and the volume and duration of the triggering stimuli. [11] Misophonic phenomena can elicit physiological, emotional, behavioral, and cognitive responses. [1,9,11,12] Emotional responses include annoyance, irritation, anger, and anxiety. ...
... [11] Misophonic phenomena can elicit physiological, emotional, behavioral, and cognitive responses. [1,9,11,12] Emotional responses include annoyance, irritation, anger, and anxiety. [1,9,11] Behavioral responses include avoidance, glaring at, or mimicking the person producing the sound, as well as verbal and physical aggression. ...
... [1,9,11,12] Emotional responses include annoyance, irritation, anger, and anxiety. [1,9,11] Behavioral responses include avoidance, glaring at, or mimicking the person producing the sound, as well as verbal and physical aggression. [12] Physical manifestations include chest, shoulder, head, or body pressure; elevated body temperature; pain; headache; and breathing difficulties. ...
Article
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Misophonia, a neurobehavioral syndrome, reduces tolerance to specific stimuli and impacts various domains of life. It is also strongly correlated with obsessive-compulsive disorder (OCD) and depression. This study aimed to investigate the prevalence of misophonia among medical students at King Saud University (KSU), Saudi Arabia, identify related sociodemographic factors, and assess misophonia association with OCD and depression. This cross-sectional study included 371 participants. The study tool was distributed electronically between November 19 and December 07, 2023. It consisted of 4 sections: a questionnaire developed by the research team, the Amsterdam Misophonia Scale (A-MISO-S), the Obsessive-Compulsive Inventory-Revised (OCI-R), and the Patient Health Questionnaire-9 (PHQ-9). The results indicated that 42.32% of the participants had previously experienced misophonia, with symptoms developing suddenly in 28.66%. The majority of participants had subclinical misophonia (71.16%) and minimal depression (37.47%), with a significant proportion experiencing mild-to-severe misophonia (28.84%) and varying degrees of depression (33.15%). Approximately 31.00% of the students exhibited likely OCD. The PHQ-9 and A-MISO-S scores showed weak positive correlations, whereas the OCI-R and A-MISO-S scores showed a moderate positive correlation. Furthermore, a moderate positive correlation was observed between the OCI-R and PHQ-9 scores. Multiple logistic regression analysis revealed that sex, family history of misophonia, depression severity, and OCD were significantly associated with clinical misophonia. This study underscores the significance of recognizing misophonia among medical students and its associated factors, such as OCD and depression. Further multicenter studies using more rigorous research methodologies are warranted.
... Recently, there has been an increasing interest in the scientific literature to comprehend the neuroanatomy and neurophysiology underlying misophonia. Researchers are actively exploring the neural mechanisms and processes associated with this disorder [8][9][10][11]. There has been debate in the literature to categorize misophonia as an auditory, psychiatric, or neurological disorder [12]. ...
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Background and Aim: Misophonia, characterized by a decreased tolerance for specific auditory stimuli, has been insufficiently explored within audiology. Limited research has been conducted, and the auditory mechanisms involved in this disorder remain to be explored. Hence, our study aimed to investigate the auditory efferent systems in individuals with misophonia. By focusing on this specific aspect, we aim to contribute to a better understanding of misophonia and shed light on the underlying auditory mechanisms involved in the condition. Methods: A cross-sectional research was performed with students from Mysore University to investigate misophonia. The severity of misophonia was evaluated using the revised Amsterdam misophonia scale. The participants were divided into two groups based on their misophonia severity: mild (n=15) and moderate-severe (n=15). All participants underwent transient evoked otoacoustic emissions with contralateral suppression to assess the auditory function. The overall amplitude and frequency-specific amplitudes were analyzed and compared across the various groups. Results: The analysis of variance results revealed no significant differences between the groups in global amplitude suppression and suppression of all frequencies. These findings imply that the medial-olivocochlear bundle efferent pathway is intact among individuals with misophonia. Conclusion: Our findings have concluded that the medial olivocochlear bundle appears intact among individuals with misophonia (p>0.05). However, it is essential to note that the generalizability of these findings may be limited due to the relatively small sample size used in our study. Therefore, further research involving a more extensive and diverse population is needed to validate and generalize these conclusions. Keywords: Misophonia; efferent pathway; contralateral suppression; neurophysiology; audiology
... S. Wu et al., 2014;Zhou et al., 2017). Schro¨der et al. (2019) and Dozier and Morrison (2017) propose that misophonia involves involuntary physical and emotional responses to trigger stimuli. Individuals with this condition frequently report deterioration in communication with family and close relationships, which can result in the breakdown of romantic partnerships, unemployment, and social isolation (Schwartz et al., 2011;Zhou et al., 2017). ...
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Misophonia is a disorder of decreased tolerance to specific sounds or stimuli associated with such sounds, called triggers. The aim was to validate a questionnaire on self-perception of the type of sound, visual identification, and origin of sounds in adults with suspected misophonia by Spanish-speaking people. An interview was conducted with a total of 395 participants, divided into four distinct blocks of questions: the trigger of misophonia, the visual identification of gestures or actions related to selective sounds, the emotional closeness between listener and sender, and the impact on the daily personal relationships of the person with misophonia. Each block used classical test theory to factorially validate the instrument. The first group of questions gave as a result four factors: mouth and throat sounds, environmental sounds, material sounds, and pronunciation sounds (Cronbach’s alpha = .929; KMO = 0.894). The second group identified two dimensions of reaction to actions and gestures, one related to movements of the mouth and throat and the second to body movements or exaggerated gesticulation (Cronbach’s alpha = .840; KMO = 0.819). The third block linked low and high emotional closeness factors (Cronbach’s alpha = .690; KMO = 0.633). The fourth block obtained a factor for daily chores and another for affective relationships (Cronbach’s alpha = .861; KMO = 0.820). The questionnaire offers valuable insights into the nature of misophonia, and the necessity for further research in this field. These findings emphasize the importance of developing a comprehensive understanding of misophonia to enhance diagnosis.
... However, these reactions depend more on psychological profiles, prior experiences, and contextual factors than on sound intensity or frequency [2,3,5]. Initially, misophonia was confused with other abnormalities, such as phonophobia; however, in most cases, typical fear reactions, such as extreme anxiety, are not observed [2,6,8,9]. Although the literature reports various reactions, such as extreme anxiety, compulsive disorders, depression, and aggression, there is no consensus among researchers regarding their occurrence in patients solely diagnosed with misophonia [6]. ...
Article
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Background/Objectives: Misophonia, characterized by strong emotional reactions to specific sounds, poses significant challenges, particularly in academic settings. This study aimed to examine the psychometric properties of the Brazilian version of the MisoQuest in a sample of high school and university students. The primary objective was to assess its reliability and structural validity to enhance understanding of misophonia in young adults. Methods: A total of 549 students (Mean age = 23.2 years, SD = 9.3; 285 females, 260 males, 4 individuals who did not disclose their gender) participated. Both exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were employed to evaluate the MisoQuest. Fit indices for unifactorial and trifactorial models were compared. Internal consistency was assessed using Cronbach’s alpha. Results: The EFA suggested a dominant single-factor structure with high factor loadings (ranging from 0.60 to 0.79). However, the CFA revealed excellent fit for both unifactorial (CFI and TLI = 1.00, RMSEA close to zero) and trifactorial models (CFI and TLI = 1.00, RMSEA = 0.037). The MisoQuest demonstrated high internal consistency (Cronbach’s alpha = 0.93). Additionally, 4.5% of participants were identified as positive for misophonia based on a predefined cutoff score of 61. Conclusions: The Brazilian version of the MisoQuest is a reliable and valid tool for assessing misophonia. These findings suggest that the instrument may capture multiple dimensions of the disorder. Given the observed prevalence of misophonia and its impact on students, early identification and tailored interventions are crucial for providing adequate support. Further research is needed to refine the tool and expand its clinical utility.
... However, these reactions depend more on psychological profiles, prior experiences, and contextual factors than on sound intensity or frequency [2,3,5]. Initially, misophonia was confused with other abnormalities, such as phonophobia; however, in most cases, typical fear reactions, such as extreme anxiety, are not observed [2,6,8,9]. Although the literature reports various reactions, such Disclaimer/Publisher's Note: The statements, opinions, and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). ...
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Misophonia, characterized by strong emotional reactions to specific sounds, poses significant challenges, particularly in academic settings. This study investigates the prevalence and psychometric properties of the MisoQuest, a tool designed to assess misophonia, in a sample of 549 high school and university students (Mean age = 23.2 years, SD = 9.3). The sample included 285 females, 260 males, and four individuals who did not disclose their gender. Using a predefined cutoff score of 61 on the MisoQuest, 4.5% of the participants were identified as positive for misophonia. Psychometric evaluation of the MisoQuest involved both exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). EFA results indicated a dominant single-factor structure, with the first factor explaining the majority of the variance. The scree plot further supported this unidimensional model. CFA confirmed the single-factor structure, with most items showing factor loadings between 0.36 and 0.58. Despite some non-significant factor loadings, the model indicated a substantial relationship between the items and the underlying factor. The high internal consistency of the MisoQuest was demonstrated by a Cronbach’s alpha coefficient of 0.93. These findings are consistent with previous studies on misophonia prevalence and support the use of the MisoQuest as a reliable assessment tool. Given the observed prevalence and the significant impact of misophonia on students’ academic and social lives, early identification and targeted support are essential. This study contributes to the understanding of misophonia in young adults and underscores the need for further research and tailored interventions.
... In line with a study by Jager et al. (2020) [4], with subjects with misophonia symptoms who were referred to mental health services, the most frequent misophonic sounds were eating, nasal and repetitive clicking/ tapping sounds. The dominance of these sound categories has also been seen in online surveys with nonclinical samples [13,19,28]. The most frequently reported misophonic emotional reaction, among those participants who reported at least one specific misophonic sound, was irritation and to a lesser extent anger and disgust, which are also specifically named in the misophonia criteria by Jager et al. (2020) [4] and the Delphi definition [15]. ...
Article
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Purpose Misophonia is a new disorder, currently defined as significant emotional and physiological distress when exposed to certain sounds. Although there is a growing body of literature on the characteristics of the disorder, the prevalence in the general population is still relatively unknown. This study therefore aims at determining the prevalence and symptom severity of misophonia in a large and representative general population sample in Germany. Methods To examine the prevalence of misophonic sounds, misophonic reactions and misophonia severity, a cross-sectional population representative survey in Germany has been conducted. Participants (N = 2.522) were questioned retrospectively about misophonic symptoms using the Amsterdam Misophonie Scale – Revised (AMISOS-R). Results Overall 33.3% reported to be sensitive to at least one specific misophonic sound. Within the total sample, subthreshold symptoms were reported by 21.3%, mild symptoms were reported by 9.9%, moderate to severe symptoms were reported by 2.1%, and severe to extreme symptoms were reported in 0.1% of participants. Conclusion Based on the diverging presentations and prevalence rates of misophonic sounds, reactions and symptoms according to the severity, it seems worthwhile to conceptualize misophonia as a rather continuous spectrum disorder (subthreshold, mild, moderate to severe), still taking into account that an additional categorical diagnostic approach might be necessary to derive a diagnosis in clinical practice.
... In extending methods identifying functional relations of escape and avoidance to other areas of practice and research that would benefit from efficient negative reinforcement assessments, we ask whether the assessments described above would fit well. Consider, for example, clinical therapy sessions for misophonia (aversion to sounds and other sense stimuli; see Dozier, 2015;Dozier & Morrison, 2017;Swedo et al., 2022;Taylor, 2017), theory testing such as with behavior interference theory (some autistic behavior resulting from escape and avoidance of self-produced sounds; Bijou & Ghezzi, 1999; see also Hixson et al., 2008), or intervention development for concerns like infant abusive head trauma, which is linked to crying (see Adamsbaum et al., 2010;Barr, 1990Barr, , 2014; see also Barr, 2001, andLummaa et al., 1998, for the survival value of infant crying). We might need alternative brief and portable assessments. ...
Article
Efficient methods for assessing the relative aversiveness of stimuli are sparse and underresearched. Having access to efficient procedures that can identify aversive stimuli would benefit researchers and practitioners alike. Across three experiments, 13 participants helped to pilot, refine, and test two approaches to identifying negative reinforcers. The first experiment presented two conditions, one in which computerized button pressing started or stopped one of two recorded infant cries (or silence, when the control button was selected). Choices were presented either in a modified observing‐response procedure (i.e., simultaneous observing) or in a modified progressive‐ratio procedure (i.e., committed concurrent progressive ratio; CCPR). Results were favorable though not conclusive on their own. A second experiment, using more distinct stimuli (i.e., one likely aversive, one likely not aversive), replicated the first, and clearer results emerged. Finally, the third experiment tested the stimuli from the second experiment in a CCPR arrangement where sound was terminated contingent on responding and idiosyncratic negative reinforcement hierarchies emerged. The utility of these two procedures is discussed, and future work that addresses the limitations is outlined.
... Numerous small-scale case studies, typically involving individual case descriptions or a series of case reports, have also been used to develop and inform an understanding of misophonia (Dozier, 2015;Dozier & Morrison, 2017). Historically, case study literature has been perceived as lacking rigour and objectivity in comparison to other research methods, however, regarding new research areas the use of case studies has been praised as being well-suited and useful for exploratory purposes (Eisenhardt, 1989). ...
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Misophonia, commonly referred to as the ‘hatred of sounds’ disorder (despite lack of official classification in the diagnostic tools), has largely been investigated with the purpose of establishing a mechanism responsible for the disorder. Perpetuating the emergence of two main gaps within the literature; i) lack of large-scale lived experience research, and ii) lack of investigation towards the online support networks that are becoming increasingly utilised and available to misophonic individuals. To address these gaps, this project utilised the r/misophonia subreddit as a data collection source to examine the presence of lived experience patterns in people with misophonia, and to assess the usefulness of online support networks. The dataset included 26 reddit posts (10 from the year 2021, and 16 from the year 2022) which were randomly sampled using an application programming interface (API), and then analysed qualitatively using reflexive thematic analysis (RTA). Overall, the findings portrayed that misophonic individuals share a plethora of lived experiences, and regarding the use of online support networks, such as the r/misophonia subreddit, these were represented as largely positive environments (via. Providing support, freedom of expression, and a place to vent). However, there were also negative implications of using online social networks, for example, they can become environments of perpetuating negativity where discussions of self-harm, and suicide may take place
Article
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Misophonia is a condition involving decreased tolerance and intense responses to specific sounds, often those that are human-generated and repetitive in nature. Misophonia frequently onsets during childhood and is associated with significant distress, impairment, and diminished quality of life. While misophonia research remains nascent and no definitive practice guidelines exist at present, extant studies offer several promising potential avenues in intervention development for adults with misophonia. However, such research is comparatively limited for youth. Before widespread adoption of promising treatments, it is important to consider the potential for harm or non-beneficence that may arise from the mis-informed application of such treatments. In this article, we identify several potential pitfalls within intervention development for pediatric misophonia and provide recommendations to circumvent them. To that end, we focus on the following three topic areas: (a) challenges arising when psychological mechanisms are not considered in intervention development, (b) importation of a cognitive-behavior therapy (CBT) framework for obsessive-compulsive spectrum disorders without nuanced tailoring to misophonia, and (c) neglecting to include individuals with lived experience in the process of intervention development research. Considering these key areas within misophonia intervention development will be critical for upholding beneficence and minimizing harm in treatment of misophonia across the lifespan.
Article
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Misophonia is a newly recognized condition involving adverse emotional reactions to environmental sounds, most often produced by other people. This study reports results of a survey describing the phenomenology of misophonia based on a large sample. Survey data were collected from individuals self-identified as having misophonia. A total of 1,061 individuals reported specific distressing reactions to sounds, and responses indicating severity of misophonia and perceived comorbidity. Over 82% of respondents were female. The average age of the study participants was 37.49 years (SD = 12.24; range from 18 to 72). Most respondents reported multiple triggers and adverse emotional reactions, as well as multiple coping responses. The majority of respondents reported comorbid diagnoses. Misophonia severity is described, as well as impact on quality of life. A minority of respondents had some experience with treatment and most reported no change in symptoms. Treatments reported for misophonia were typically ineffective, and once developed, misophonia symptoms persist. The results of the study showed that misophonia is a newly recognized condition that appears to have important impact on people’s lives. It typically develops in early life, and is associated with a reduced quality of life, substantial comorbidity, negative emotional experiences, and behaviors that are likely to impact interpersonal relationships.
Book
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Does the sound of other people chewing fill you with rage? Do certain sights and sounds make you crazy when they don’t bother anyone else? If so, you are not alone. Although rarely known, misophonia is quite common, and there is hope. Misophonia is a neurological condition where a person has a strong emotional response of anger or disgust to specific sounds. For some, it might be hearing someone chewing. For others, it is the sound of sniffling or breathing. Many people also have the misophonic response to visual triggers such as seeing someone chew gum. With misophonia, a person has specific soft sounds (and sights) that they cannot tolerate. Misophonia can be upsetting and annoying, or it can be a debilitating condition. It may vary in intensity but generally gets worse with time. There are important management techniques that are helpful to almost everyone. Although there are no proven treatments that work for everyone, there are treatments that work for many. With proper management and treatment there is hope for reducing the horrible effects of this condition. This book will help you understand what this mysterious condition is doing to you, or help you understand what someone close to you is experiencing. It explains how misophonia develops and expands with time, and why those little sounds cause a person SO much distress. It also gives you many techniques that will help you manage this condition and explores the existing treatment options. With proper management and treatment, you can greatly reduce the effects of misophonia in your life. Developing misophonia has been a journey. Overcoming misophonia is also a journey, and it is a journey that can provide much relief for this horrible condition.
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Misophonia is a condition in which a person has an acute emotional response of anger or disgust to a commonly occurring innocuous auditory or visual stimulus referred to as a trigger. This case details the effective treatment of misophonia in a young woman that included a counterconditioning treatment called the Neural Repatterning Technique (NRT), which combines a continuous positive stimulus and a reduced intensity, intermittent trigger. The treatment was delivered via the Misophonia Trigger Tamer smartphone app and all treatments were conducted independently by the patient. In this patient, the trigger elicited a physical reflex of contraction of the flexor digitorum profundus, which caused her to clench her fist. To enhance the effect of the NRT treatment, Progressive Muscle Relaxation was incorporated to increase her ability to deliberately relax the affected muscle during treatment. During NRT treatment sessions, the patient experienced a weak physical reflex to the reduced trigger stimulus but no emotional response. Her emotional response of misophonia was not treated, but when the physical reflex extinguished, the emotional response also extinguished. This case indicates that the misophonic response includes a Pavlovian-conditioned physical reflex. It is proposed that the trigger elicited the physical reflex and the physical reflex then elicited the conditioned emotional response that is characteristic of misophonia. Because of the conditioned reflex nature of misophonia, it is proposed that a more appropriate name for this disorder would be Conditioned Aversive Reflex Disorder.
Article
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Misophonia is a recently identified condition in which an individual has an acute reaction of hatred or disgust to a specific commonly occurring sound. We propose that misophonia is a form of conditioned behavior that develops as a physical reflex through Pavlovian conditioning. Although misophonia is generally considered to be a one-step reaction, in which the sound elicits rage or disgust, as well as typical autonomic responses associated with these emotions, we propose that misophonia is a two-step reaction, in which the sound elicits an aversive conditioned physical reflex, and the aversive conditioned physical reflex elicits hatred or disgust. We also propose that the emotional response to trigger stimuli creates a Pavlovian conditioning paradigm that maintains or strengthens the misophonic physical reflex. Finally, we propose that new misophonic trigger stimuli are developed through the pairing of a neutral stimulus with a misophonic trigger stimulus. We suggest that a better name for misophonia is Conditioned Aversive Reflex Disorder (CARD) since it focuses attention on the reflexive nature of this condition and incorporates multiple stimuli modalities. A counterconditioning treatment for misophonia is presented with brief case descriptions which demonstrate the conditioned reflex nature of this disorder.
Article
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Misophonia is a recently identified discrete and independent condition that cannot be classified using DSM-V criteria. With misophonia, a trigger stimulus elicits a reaction starting with irritation or disgust that immediately escalates. The trigger stimulus can be any typically occurring sound. The reaction is both extreme and irrational, and can include feelings of hate, anger, rage, and disgust. This response is perceived as involuntary, and individuals report feeling a loss of self-control. Misophonia can be conceptualized as a conditioned response to the trigger stimulus. This article describes a counterconditioning treatment of a middle-aged woman for misophonia that involved pairing a positive stimulus with a reduced trigger stimulus. Under these conditions, the misophonic response to the stimulus progressively weakened. Four distinct trigger stimuli were addressed in a multiple baseline treatment format. The overall severity of misophonia and the strength of the misophonic responses to triggers reduced over the course of the treatment, based on client self-assessments. These indicated large reductions in severity of misophonia and response to individual triggers, both at the end of treatment and at 10 months posttreatment. During treatment, responses to low intensity trigger stimuli were purely physical and independent of any emotional response. This demonstrated that, in this case, misophonia included a conditioned physical reflex to the trigger stimulus. It is proposed that misophonia consists of an aversive physical reflex elicited by the trigger stimulus and an emotional response elicited by the aversive physical reflex.
Article
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Decreased sound tolerance (DST) is an underappreciated condition that affects the lives of a significant portion of the general population. There is lack of agreement regarding definitions, specific components, prevalence, methods of evaluation, and methods of treatment. Limited data are available on the results of treatments. Research is scant and constrained by the lack of an animal model. This article proposes a definition of DST and its division into hyperacusis and misophonia. The potential mechanisms of these phenomena are outlined, and the results of treatment performed at Emory University are presented. Out of 201 patients with DST, 165 (82%) showed significant improvement. Of 56 patients with hyperacusis (with or without misophonia), 45 (80%) showed significant improvement. This proportion was higher for the group with hyperacusis and concurrent misophonia (33 of 39, or 85%) and lower for patients with hyperacusis only (13 of 17, or 76%). Effectiveness of treatment for misophonia with or without hyperacusis was identical (152 of 184, 83% and 139 of 167, 83%, respectively, for misophonia accompanied by hyperacusis and for misophonia only). Even with current limited knowledge of DST, it is possible to propose specific mechanisms of hyperacusis and misophonia and, based on these mechanisms, to offer treatments in accordance with the neurophysiological model of tinnitus. These treatments are part of Tinnitus Retraining Therapy (TRT), which is aimed at concurrently treating tinnitus and DST and alleviating the effects of hearing loss. High effectiveness of the proposed treatments support the postulated mechanisms.
Article
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The main objective of Tinnitus Retraining Therapy (TRT) is habituation of activation of the autonomic nervous system, evoked by signals present in the auditory pathways. Sound therapy aims at decreasing the strength of these signals. The same systems in the brain are involved in tinnitus and decreased sound tolerance, and the same basic neurophysiological mechanisms are utilised for decreasing the tinnitusrelated neuronal activity and, in case of hyperacusis, abnormally enhanced activity induced by external sounds. The similarity of TRT treatment between tinnitus and misophonia is even closer, as in both situations the goal is to achieve extinction of functional connections between the auditory and the limbic and autonomic nervous systems. The increased gain within the auditory pathways that are presumably responsible for hyperacusis could enhance the tinnitus signal, thus it is possible to expect coexistence of tinnitus and hyperacusis, and the predisposition of hyperacusis patients to develop tinnitus. As such, for some patients tinnitus and hyperacusis may be considered the double manifestation of the same internal phenomenon.
Article
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Misophonia is a relatively unexplored chronic condition in which a person experiences autonomic arousal (analogous to an involuntary “fight-or-flight” response) to certain innocuous or repetitive sounds such as chewing, pen clicking, and lip smacking. Misophonics report anxiety, panic, and rage when exposed to trigger sounds, compromising their ability to complete everyday tasks and engage in healthy and normal social interactions. Across two experiments, we measured behavioral and physiological characteristics of the condition. Interviews (Experiment 1) with misophonics showed that the most problematic sounds are generally related to other people's behavior (pen clicking, chewing sounds). Misophonics are however not bothered when they produce these “trigger” sounds themselves, and some report mimicry as a coping strategy. Next, (Experiment 2) we tested the hypothesis that misophonics' subjective experiences evoke an anomalous physiological response to certain auditory stimuli. Misophonic individuals showed heightened ratings and skin conductance responses (SCRs) to auditory, but not visual stimuli, relative to a group of typically developed controls, supporting this general viewpoint and indicating that misophonia is a disorder that produces distinct autonomic effects not seen in typically developed individuals.
Article
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Background Some patients report a preoccupation with a specific aversive human sound that triggers impulsive aggression. This condition is relatively unknown and has hitherto never been described, although the phenomenon has anecdotally been named misophonia. Methodology and Principal Findings 42 patients who reported misophonia were recruited by our hospital website. All patients were interviewed by an experienced psychiatrist and were screened with an adapted version of the Y-BOCS, HAM-D, HAM-A, SCL-90 and SCID II. The misophonia patients shared a similar pattern of symptoms in which an auditory or visual stimulus provoked an immediate aversive physical reaction with anger, disgust and impulsive aggression. The intensity of these emotions caused subsequent obsessions with the cue, avoidance and social dysfunctioning with intense suffering. The symptoms cannot be classified in the current nosological DSM-IV TR or ICD-10 systems. Conclusions We suggest that misophonia should be classified as a discrete psychiatric disorder. Diagnostic criteria could help to officially recognize the patients and the disorder, improve its identification by professional health carers, and encourage scientific research.
Article
Objective Individuals with misophonia display extreme sensitivities to selective sounds, often resulting in negative emotions and subsequent maladaptive behaviors, such as avoidance and anger outbursts. While there has been increasing interest in misophonia, few data have been published to date.Method This study investigated the incidence, phenomenology, correlates, and impairment associated with misophonia symptoms in 483 undergraduate students through self-report measures.ResultsMisophonia was a relatively common phenomenon, with nearly 20% of the sample reporting clinically significant misophonia symptoms. Furthermore, misophonia symptoms demonstrated strong associations with measures of impairment and general sensory sensitivities, and moderate associations with obsessive-compulsive, anxiety, and depressive symptoms. Anxiety mediated the relationship between misophonia and anger outbursts.Conclusion This investigation contributes to a better understanding of misophonia and indicates potential factors that may co-occur and influence the clinical presentation of a person with misophonia symptoms.