The study examined the contribution of the key variables in poultry (broiler and layer) production and identified the major problems and constraints of poultry farmers in some rural areas of Bangladesh. The study was based on a sample survey of randomly selected 60 poultry farms of which 30 were layer farms and 30 were broiler farms at two Upazilas of Jessore district in 2011. Regression analysis was used to determine the effect of the inputs in poultry production. The study revealed that various inputs including feed, treatment and day old chick were positively affected the production of poultry. Study also reveled that farmers, in general, allocated their resources in the first stage of production for layer farm and in the second stage of production for broiler farm. The study identified major problems such as, high price of feed, outbreak of diseases, lack of steady supply of electricity, lack of veterinary care and service facilities, inadequate knowledge on poultry husbandry, non-availability of chickens and lack of credit which should be mitigated as early as possible with an interest to accelerate commercial poultry production in rural Bangladesh.