Calophyllum inophyllum Linn. (Clusiaceae) is a medicinal plant, distributed in many countries of the tropics and subtropics. It has an otablenumber of medicinal properties with high curative value. C. inophyllum is very important for its medicinal value. Various parts of this plant such as the leaves, bark, flowers, fruits and seeds were used for the treatment of different ailments in the indigenous system of medicine such as skin diseases, wounds, ulsers, vaginal discharge and the passing of blood after child birth, gonorrhoea, chronic bronchitis, phthisis, sore eyes, heatstroke, migraine and vertigo, and are being employed as antiseptics, astringents, expectorants, diuretics and purgatives particularly in South Asia. Hence, this review focuses on the detailed medicinal uses, phytochemical composition, along with pharmacological properties of this multipurpose C. Inophyllum tree.