The aim of this study was to examine the effect of two different lower body strength training schemes on upper body adaptations to resistance training. Twenty resistance-trained males (4.25+/-1.6 y of experience) were randomly assigned to either a high-intensity (HI; n=9; age=24.9+/-2.9 y; body mass=88.7+/-17.2 kg; height=177.0+/-5.6 cm) or a mixed high-volume and high-intensity resistance training program (MP; n=11; age=26.0+/-4.7 y; body mass=82.8+/-9.1 kg; height=177.54+/-5.9 cm). HI group followed a high-intensity training for both upper and lower body (4-5 reps at 88-90% of 1-RM), while the MP group performed high-volume training sessions focused on muscle hypertrophy for lower body (10-12 reps at 65-70% of 1-RM) and a high-intensity protocol for the upper body. Maximal strength and power testing occurred before and after the 6-week training program. Analysis of covariance was used to compare performance measures between the groups. Greater increases in MP groups compare to HI group were observed for bench press 1-RM (p = 0.007), bench press power at 50 % of 1-RM (p = 0.011) and for AMA (p = 0.046). Significant difference between the two groups at post-test were also observed for fat mass (p = 0.009). Results indicated that training programs focused on lower body muscle hypertrophy and maximal strength for upper body, can stimulate greater strength and power gains in the upper body compared to high-intensity resistance training programs for both the upper and lower body.