Epidemiological and nutritional studies indicate that cucumbers, a fruit in the cucurbitaceae family, have numerous benefits internally, externally and even emotionally. As a food, cucumbers offer superior hydration, as they are about 95% water. They have been used for decades for their anti-inflammatory benefits on skin, soothing properties for digestion, and other therapeutic uses. The following contribution offers an overview of cucumbers, specifically, their use to augment cellular water and address common conditions (i.e.: skin discoloration and aging, cardiovascular and cancerous diseases, bone health, inflammation, and connective tissue disorders).