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Teeth periapical lesion prediction using machine learning techniques

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... It showed the use of AI in dental research increases from one paper in 2008 to 20 in 2019. It includes detection and diagnosis of dental caries, proximal dental caries, VRF, apical lesions and so on [9][10][11][12][13][14][15][16][17][18][19][20]. ...
... It showed the use of AI in dental research increases from one paper in 2008 to 20 in 2019. It includes detection and diagnosis of dental caries, proximal dental caries, VRF, apical lesions and so on [9][10][11][12][13][14][15][16][17][18][19][20]. Most cases of AI medical applications mention deep learning used in their study [21][22][23]. ...
... In most cases, deep learning (DL) is achieved by neural networks (NNs). These neural networks include artificial neural networks (ANNs) [10][11][12], convolutional neural networks [13][14][15][16][17][18], Bayesian neural networks (BNNs) [19] and probabilistic neural networks (PNNs) [20]. ANN is the kernel architecture in this study. ...
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Predicting the risk of root fractures following root canal therapy requires diagnosis of the dental history and status of patients. However, dental history is a kind of categorical data type that is not easy to combine with numerical data to obtain good performance in deep learning. The accuracy of support vector machine (SVM) and artificial neural networks (ANNs) is 71.7% and 73.1%, respectively. In this study, a three-stage fusion neural network (TSFNN) is proposed to improve the multiple types of clinical data in the dental field based on ANNs. Clinical data were obtained from 145 teeth, comprising 97 fractured teeth and 48 nonfractured teeth. Each dataset contained 17 items, which were divided into 10 categorical items and 7 numerical items. TSFNN combines numerical and categorical NN with batch normalization and embedding layer techniques and can produce the accuracy of 82.1% and a 19.1% improvement in F1-score. It shows impressive performance in predicting the risk of root fracture. Furthermore, due to the limited amount of clinical data, it is believed that such a pilot study can effectively improve the results when the amount of clinical data is insufficient.
... In comparison with traditional methods, ML models offer higher accuracy and consistency as they can automatically process and analyse a large quantity of dental radiographs, through learning the patterns and characteristics associated with certain dental condition, identifying signs that might not be visible for dentists' eyes with reliable diagnostic results. Different ML models are applied in various dental symptoms, based on various types of algorithms to analyse radiographs (panoramic X-ray [65], periapical [66], cephalometric [67], etc.), intraoral [68] or histopathological images [69], facilitating timely intervention, and development of personalised preventive strategies. Moreover, predictive and differentiate analytics on the management of temporomandibular disorders (TMD) [70] or progression [71] of dental diseases such as periodontal and apical lesions (cysts, granulomas and abscesses) also guide clinicians in selecting the most appropriate treatment plans tailored to individual patients. ...
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Background: Machine learning (ML) is transforming dentistry by setting new standards for precision and efficiency in clinical practice, while driving improvements in care delivery and quality. Objectives: This review: (1) states the necessity to develop ML in dentistry for the purpose of breaking the limitations of traditional dental technologies; (2) discusses the principles of ML-based models utilised in dental clinical practice and care; (3) outlines the application respects of ML in dentistry; and (4) highlights the prospects and challenges to be addressed. Data and sources: In this narrative review, a comprehensive search was conducted in PubMed/MEDLINE, Web of Science, ScienceDirect, and Institute of Electrical and Electronics Engineers (IEEE) Xplore databases. Conclusions: Machine Learning has demonstrated significant potential in dentistry with its intelligently assistive function, promoting diagnostic efficiency, personalised treatment plans and related streamline workflows. However, challenges related to data privacy, security, interpretability, and ethical considerations were highly urgent to be addressed in the next review, with the objective of creating a backdrop for future research in this rapidly expanding arena. Clinical significance: Development of ML brought transformative impact in the fields of dentistry, from diagnostic, personalised treatment plan to dental care workflows. Particularly, integrating ML-based models with diagnostic tools will significantly enhance the diagnostic efficiency and precision in dental surgeries and treatments.
... K-nearest neighbour It is a classification and regression model which operates on the principle of proximity, identifying the 'k' closest data instances to the new query point and predicting the label based on the predominant category among these neighbours (Sajad et al., 2019) The diagnosis of periapical lesions in teeth (Mahmoud et al., 2016) Linear regression It is a method that establishes a linear relationship between a dependent variable and one or more independent variables through a fitted linear equation. It is a critical tool in research for quantifying and predicting the influence of independent factors on an outcome of interest (Su et al., 2012) Predicting case difficulty in endodontic microsurgery (Qu et al., 2023), and assessing the impact of different demographic variables on the volumetric changes in external cervical resorption defects Decision tree Decision trees are a type of model used for making predictions. ...
Article
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The integration of artificial intelligence (AI) in healthcare has seen significant advancements, particularly in areas requiring image interpretation. Endodontics, a specialty within dentistry, stands to benefit immensely from AI applications, especially in interpreting radiographic images. However, there is a knowledge gap among endodontists regarding the fundamentals of machine learning and deep learning, hindering the full utilization of AI in this field. This narrative review aims to: (A) elaborate on the basic principles of machine learning and deep learning and present the basics of neural network architectures; (B) explain the workflow for developing AI solutions, from data collection through clinical integration; (C) discuss specific AI tasks and applications relevant to endodontic diagnosis and treatment. The article shows that AI offers diverse practical applications in endodontics. Computer vision methods help analyse images while natural language processing extracts insights from text. With robust validation, these techniques can enhance diagnosis, treatment planning, education, and patient care. In conclusion, AI holds significant potential to benefit endodontic research, practice, and education. Successful integration requires an evolving partnership between clinicians, computer scientists, and industry.
... Accuracy is an important evaluation indicator in neural network models. To calculate the accuracy, the concepts of true positive (TP), true negative (TN), false positive (FP), and false negative (FN) are introduced [49]. ...
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With a view of the post-COVID-19 world and probable future pandemics, this paper presents an Internet of Things (IoT)-based automated healthcare diagnosis model that employs a mixed approach using data augmentation, transfer learning, and deep learning techniques and does not require physical interaction between the patient and physician. Through a user-friendly graphic user interface and availability of suitable computing power on smart devices, the embedded artificial intelligence allows the proposed model to be effectively used by a layperson without the need for a dental expert by indicating any issues with the teeth and subsequent treatment options. The proposed method involves multiple processes, including data acquisition using IoT devices, data preprocessing, deep learning-based feature extraction, and classification through an unsupervised neural network. The dataset contains multiple periapical X-rays of five different types of lesions obtained through an IoT device mounted within the mouth guard. A pretrained AlexNet, a fast GPU implementation of a convolutional neural network (CNN), is fine-tuned using data augmentation and transfer learning and employed to extract the suitable feature set. The data augmentation avoids overtraining, whereas accuracy is improved by transfer learning. Later, support vector machine (SVM) and the K-nearest neighbors (KNN) classifiers are trained for lesion classification. It was found that the proposed automated model based on the AlexNet extraction mechanism followed by the SVM classifier achieved an accuracy of 98%, showing the effectiveness of the presented approach.
... There were unexpected findings, with a mean accuracy of roughly 77.2%, and the authors stated that the reference method was better than this approach, but that the results may be improved in future work utilizing optimization techniques. [29] Setzer et al. [30] concluded that a DL algorithm trained in a constrained CBCT setting produced high lesion detection accuracy. Enhanced versions of AI may improve overall voxel-matching accuracy, thus, revealing an accuracy of 93% for this study. ...
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Aim: With the help of developments in artificial intelligence (AI), picture archiving systems, and computer-aided diagnostic systems, dentists have been able to augment the quality of treatment and ensure a favorable outcome, by improving and facilitating the delivery of appropriate dental care. There has been a breakthrough in designing the diagnosis, treatment plans, and predicting prognoses recently, which has helped to explore newer options for better treatment. Materials and Methods: A literature search was conducted using MeSH terms in a variety of databases, including PubMed, Cochrane, Scopus, and Web of Science, to gather information on “Artificial intelligence (AI) in endodontics.” Unpublished data, literature written in other languages, and articles with only abstracts were discarded. Forty-one relevant articles were included. Results: Since there were not many papers referring to AI in endodontics, papers published relating to AI in dentistry were also referred. The search showed that the use of AI in dentistry, specifically in endodontics, has enormous promise. Although useful, AI has its disadvantages as well as the need for long-term studies. Conclusion: AI, consisting of a sequence of algorithms, work on a concept that mimics the human brain and thinking. AI in endodontics has been used widely in locating apical foramina, identifying periapical pathologies, diagnosis of vertical root fractures, evaluating the outcome of regenerative procedures and retreatments, and assessment of root morphologies and difficulties associated with canal preparations. Being a potential game changer and beginning something called a “fourth industrial revolution,” AI has what it takes to revolutionize endodontics with time.
... The frequent benefits of AI application in endodontics are mentioned as analyzing root canal anatomy, detecting root fractures, and periapical lesions, precise assessment of working length, predicting the viability of dental pulp stem cells, and predicting the success rate of retreatment procedures [101]. [105][106][107]. Therefore, the possible application of AI for periapical lesions detection in the future should be further examined [102]. ...
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Statement of the Problem In recent years, the use of artificial intelligence (AI) has become increasingly popular in dentistry because it facilitates the process of diagnosis and clinical decision-making. However, AI holds multiple prominent drawbacks, which restrict its wide application today. It is necessary for dentists to be aware of AI's pros and cons before its implementation. Purpose Therefore, the present study was conducted to comprehensively review various applications of AI in all dental branches along with its advantages and disadvantages. Materials and Method For this review article, a complete query was carried out on PubMed and Google Scholar databases and the studies published during 2010-2022 were collected using the keywords "Artificial Intelligence”, "Dentistry," "Machine learning," "Deep learning," and "Diagnostic System." Ultimately, 116 relevant articles focused on artificial intelligence in dentistry were selected and evaluated. Results In new research AI applications in detecting dental abnormalities and oral malignancies based on radiographic view and histopathological features, designing dental implants and crowns, determining tooth preparation finishing line, analyzing growth patterns, estimating biological age, predicting the viability of dental pulp stem cells, analyzing the gene expression of periapical lesions, forensic dentistry, and predicting the success rate of treatments, have been mentioned. Despite AI's benefits in clinical dentistry, three controversial challenges including ease of use, financial return on investment, and evidence of performance exist and need to be managed. Conclusion As evidenced by the obtained results, the most crucial progression of AI is in oral malignancies' diagnostic systems. However, AI's newest advancements in various branches of dentistry require further scientific work before being applied to clinical practice. Moreover, the immense use of AI in clinical dentistry is only achievable when its challenges are appropriately managed.
... Applicability concerns were found to be high for 53% of the studies regarding data selection but were low for most studies regarding the index test (79%) and reference standard (73%). [13] low/low low/low low/low low 3. [14] high/low low/low low/low low 4. [15] low/low low/high high/high low 5. [16] low/low low/low low/low low 6. [17] high/high low/high high/high low 7. [18] high/high low/low high/low low 8. [19] low/low low/high low/low low 9. [20] low/low low/low low/high low 10. [21] high/high low/low high/low low 11. ...
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Machine learning (ML) is being increasingly employed in dental research and application. We aimed to systematically compile studies using ML in dentistry and assess their methodological quality, including the risk of bias and reporting standards. We evaluated studies employing ML in dentistry published from 1 January 2015 to 31 May 2021 on MEDLINE, IEEE Xplore, and arXiv. We assessed publication trends and the distribution of ML tasks (classification, object detection, semantic segmentation, instance segmentation, and generation) in different clinical fields. We appraised the risk of bias and adherence to reporting standards, using the QUADAS-2 and TRIPOD checklists, respectively. Out of 183 identified studies, 168 were included, focusing on various ML tasks and employing a broad range of ML models, input data, data sources, strategies to generate reference tests, and performance metrics. Classification tasks were most common. Forty-two different metrics were used to evaluate model performances, with accuracy, sensitivity, precision, and intersection-over-union being the most common. We observed considerable risk of bias and moderate adherence to reporting standards which hampers replication of results. A minimum (core) set of outcome and outcome metrics is necessary to facilitate comparisons across studies.
... This review has shown one great challenge with the current literature on AI in dentistry; the presence of computer-based papers without proper understanding of relevant input data from a clinical point of view. Also, there are several models which are not trained based on clinical rigorous data [49,50] (Table 3). Therefore the outputs of such models are unreliable regardless of the accuracy metrics reported [48]. ...
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Objectives: To assess the efficiency of AI methods in finding radiographic features in Endodontic treatment considerations. Material and methods: This review was based on the PRISMA guidelines and QUADAS 2 tool. A systematic search was performed of the literature on cases with endodontic treatments, comparing AI algorithms (test) versus conventional image assessments (control) for finding radiographic features . The search was conducted in PubMed, Scopus, Google Scholar and the Cochrane library. Inclusion criteria were studies on the use of AI and machine learning in endodontic treatments using dental X-rays. Results: The initial search retrieved 1131 papers, from which 24 were included. High heterogeneity of the materials left out a meta-analysis.The reported subcategories were periapical lesion, vertical root fractures, predicting root/canal morphology, locating minor apical foramen, tooth segmentation and endodontic retreatment prediction. Radiographic features assessed were mostly periapical lesions. The studies mostly considered the decision of 1-3 experts as the reference for training their models. Almost half of the included materials campared their trained neural network model with other methods. More than 58% of studies had some level of bias. Conclusions: AI-based models have shown effectiveness in finding radiographic features in different endodontic treatments. While the reported accuracy measurements seem promising, the papers mostly were biased methodologically.
... The frequent benefits of AI application in endodontics are mentioned as analyzing root canal anatomy, detecting root fractures, and periapical lesions, precise assessment of working length, predicting the viability of dental pulp stem cells, and predicting the success rate of retreatment procedures [101]. [105][106][107]. Therefore, the possible application of AI for periapical lesions detection in the future should be further examined [102]. ...
Preprint
Statement of the Problem: In recent years, the use of Artificial Intelligence has become increasingly popular in dentistry because it facilitates the process of diagnosis and clinical decision-making. However, this novel technology lacks frequent prominent elements which restrict its wide application today. It is necessary for dentists to be aware of AI's pros and cons before its implementation. Purpose: Therefore, the present study was conducted to comprehensively review various applications of AI in all dental branches along with its advantages and disadvantages. Materials and Method: For this review article, a complete query was carried out on PubMed and Google Scholar databases and the studies published during 2010-2022 were collected using the keywords "Artificial Intelligence," "Dentistry," "Machine learning," "Deep learning," and "Diagnostic System." Ultimately, 116 relevant articles focused on artificial intelligence in dentistry were selected and evaluated. Results: In new research AI applications in detecting dental abnormalities and oral malignancies based on radiographic view and histopathological features, designing dental implants and crowns, determining tooth preparation finishing line, analyzing growth patterns, estimating biological age, predicting the viability of dental pulp stem cells, analyzing the gene expression of periapical lesions, forensic dentistry, and predicting the success rate of treatments, have been mentioned. Despite AI's benefits in clinical dentistry, 3 controversial challenges including ease of use, financial return on investment, and evidence of performance exist and need to be managed. Conclusion: As evidenced by the obtained results, the most crucial progression of AI is in oral malignancies' diagnostic systems. However, AI's newest advancements in various branches of dentistry require further scientific work before being applied to clinical practice. Moreover, the immense use of AI in clinical dentistry is only achievable when its challenges are appropriately managed. Keywords: Artificial Intelligence, Dentistry, Machine learning, Deep learning, Diagnostic System
... These steps are followed for each experiment performed on the dataset for the classification using a machine and deep learning. [7]. the main pattern in dental disease detection is all the parameters should be addressed to classify the diseases [8] because, the disease type and severity is not common in all data, it was varied based on different patients [9]. ...
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Artificial intelligence (AI) is emerging as a transformative technology in healthcare, including endodontics. A gap in knowledge exists in understanding AI's applications and limitations among endodontic experts. This comprehensive review aims to (A) elaborate on technical and ethical aspects of using data to implement AI models in endodontics; (B) elaborate on evaluation metrics; (C) review the current applications of AI in endodontics; and (D) review the limitations and barriers to real-world implementation of AI in the field of endodontics and its future potentials/directions. The article shows that AI techniques have been applied in endodontics for critical tasks such as detection of radiolucent lesions, analysis of root canal morphology, prediction of treatment outcome and post-operative pain and more. Deep learning models like convolutional neural networks demonstrate high accuracy in these applications. However, challenges remain regarding model interpretability, generalizability, and adoption into clinical practice. When thoughtfully implemented, AI has great potential to aid with diagnostics, treatment planning, clinical interventions, and education in the field of endodontics. However, concerted efforts are still needed to address limitations and to facilitate integration into clinical workflows.
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