The term Anthropocene has been introduced to highlight the fact humans have, directly or indirectly – accidentally or intentionally – profoundly transformed the earth system. There is much debate as to whether the magnitude and extent of such change is geologically distinctive and, accordingly, warrants formal designation as a new epoch although, irrespective of this, the magnitude of change is undoubtedly significant. In order to put the Anthropocene into perspective, the chapter briefly reviews various systemic and cumulative drivers of geomorphic change before going on to explore the time-transgressive impacts of humans on virtually all environments of the earth. This is followed by a consideration of three instructive case studies of how the deleterious effects of growing numbers of people using increasingly sophisticated technologies are expressed geomorphologically across a range of environments. The problems of accelerated soil erosion, the impact of large dams and the nature and extent of artificial ground are used to highlight the important role that geomorphology plays in understanding the burgeoning footprint of humanity on earth systems. The Quaternary record offers a foundational understanding of baseline conditions of earth system processes and responses and facilitates increased confidence in evaluating the magnitude of past and future global climate change and its diverse effects. A quarter of a century on from the first IPCC report, the degree to which the strength of its statements, and the confidence with which they are made, is rooted in a better understanding of longer-term past changes should not be underestimated. The fact that geomorphology may still be a ‘Cinderella’ in relation to studies of environmental change is ongoing cause for concern and, if we are to illuminate the range of options available to mitigate and adapt to future change, we need systematically to incorporate a stronger geomorphological perspective into global change science; the Anthropocene represents an appropriate platform from which to inject that perspective.