Practice demonstrates that most of existing methods and techniques of adjustment of the automatic control systems cannot provide the appropriate quality of the systems performing. That is why nowadays main attention is paid to adaptive methods and algorithms. In this paper, the Real Interpolation Method is offered for creation of adaptive Automatic Control Systems. It is based on use of a special case of the Laplace transformation, when the complex variable p = δ + jω comes to real part 5. Due to this approach the number of operations is decreased more than twice in comparison with the frequency domain methods and it considerably simplifies algorithms of self-adjustment of Automatic Control Systems.