This article discusses the theory of the Metaplastic discipline for the study and the realization of new virtual media through interdisciplinary methodologies between reality and virtual realities. It explains the theoretical and artistic background of metaplastic virtual worlds evolutions, from their archetypes to their definition. The union between plastic elements and the fuzzy logic systems,
... [Show full abstract] found their expression with new metaplastic semantic and aesthetic values. The virtual media acquire form and meaning through its process of conceptual interpretation. The metaphor of the artistic machine finds its new realization where the metaplastic machine itself becomes aesthetic expression of the virtuality. The following paragraphs use metaplastic definitions within Design, Art, and Sciences application fields. The Open Metaplastic framework’s general approach applied to software and hardware modeling design are discussed.