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[Population health risk from chemical air pollutants in a city with developed pulp and paper industry]

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Abstract

Objective: to assess an effect of chemical contaminants contained in emissions of pulp and paper mill on prevalence respiratory and cardiovascular diseases in population of Novodvinsk. The average annual concentrations of chemicals of concern were calculated by modeling. A prevalence of population was studied by using of the primary medical documentation in sex among children from 0 to 17 and adults from 65 and older Hazard index (HIi) was used to assess the non-cancer health effects. Unit risk was used to calculate individual cancer risk (CR). Testing of null hypothesis was conducted by one-way analysis of variance (ANOVA) and ?2. The hazard index for respiratory tract (HIi = 3,54; 95% CI: 3.34-3.70) and cardiovascular system (HIi = 0.78; 95% /DE: 0.74-0.82) in the district close to the Arkhangelsk pulp and paper mill (APPM) were higher than in remote districts. In this district the prevalence of bronchial asthma in boys (30.7+13.8%), women (47.0+9.8%) and men (127.4+45.2%) was the highest. Also in this district the prevalence of hypertension among women (139.1+14.4%) and men (311.5+56.1%), diseases of veins among women (48.2+10.8%) and diseases of upper respiratory tract among men (177.0+36.4%) was higher than in remote districts from the APPM. The level of CR in the district located close by the APPM was acceptable (1.0 (10-5; 95% CI: 9.0 (10-6-1, 18(10-5).

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... As of date, air pollution and its influence on health of population is one of the most actual problems [3,5,8,9]. Analysis of clinical and experimental works proved direct correlation dependency of the level of air pollution and frequency of origin of pulmonary pathology [2,7,[10][11][12]. ...
... As of date, air pollution and its influence on health of population is one of the most actual problems [3, 5, 8, 9]. Analysis of clinical and experimental works proved direct correlation dependency of the level of air pollution and frequency of origin of pulmonary pathology [2, 7,101112. It has been established that the main pathogenetic link in the development of pulmonary diseases is disorder of the surface activity of lung surfactant, whose synthesis and secretion is done by the alveolocytes of II type [1, 6]. ...
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