Effect of gelatin-cystine and serenoa repens extract on free radicals level and hair growth
The influence of gelatin-cystine and serenoa repens on hair growth was studied through a long period application (50 weeks) of a new cosmeceutical lotion. On 48 volunteers (24 women and 24 men) aged between 21 and 38 years, affected by androgenetic alopecia (type III and IV according to Hamilton). 12 subjects also took a diet supplement (4 pills per day) based on gelatin- cystine. The solution and the diet supplement (placebo and active) were assigned in a randomized double-blind manner. Hair mass and the mean hair number were controlled according to Price et al. Exclusion criteria included use of topical or oral drug or diet supplement within the previous six months. The obtained results showed an increase of hair mass from 20 to 30% (p<0.005) together with a contemporary increase of hair number (from 17 to 27%) (p<0.005) compared to the placebo for subjects using the lotion only. With the diet supplement a further increase of 50% (p<0.005) in hair growth and a significant decrease of blood ROS (Reactive Oxigen Species) were obtained.