Innovation has become widely scrutinized and currently mobilizes many scientific fields in its investigation. However, there is a need for greater diligence when conducting these studies due to innovation’s broad sense and complex dynamics, ranging from individual up to entire economic, political and social systems analysis. This variety makes the organization of what has been studied about innovation an arduous task and may overshadow the collective efforts that culminated in the emergence of the innovation studies field, which has gathered many scholars and research centers around it. Within this emergent field the systems of innovation approach became central given its systemic and interconnected assessment of innovation and its dynamics. Stemming originally from evolutionary economics, this approach is cross disciplinary, involves varied contributions in social sciences and has been vital in terms of knowledge used in policy making, industrial, educational, financial and organizational spheres. The national innovation systems is the most notorious of the systems of innovation approaches and portrays innovation as a process of constant interaction, learning and knowledge flows between its components and activities. These national systems’ most relevant components are government, universities, industries and financial institutions. There are however, other institutions and organizations that interact among these main components that have only recently been investigated as innovation intermediaries, a theoretical framework that focuses on the actors that indirectly enable innovation. Science parks are an example of intermediary components in innovation systems and have been studied over decades, however, their results and positive impacts are still contested by scholars. Despite the fact that these science parks have been largely studied in isolation, it was noticed that they are also collectively represented by many associations in regional, national and international contexts. After identifying that these associations remained uninvestigated, the present thesis combines national innovation systems and innovation intermediaries to analyze associations of science parks in order to better understand their relevance in innovation processes as well as their relations with innovation systems. In a research of qualitative nature, we conducted a bibliographic research, a multiple case study of AURP Canada, Anprotec and IASP, triangulating this data with others from a documental research. The results indicate that the analyzed cases are indeed innovation intermediaries since they present ties with other systemic components and provide various services for their members that enables their innovation efforts. The most relevant services to members are those of information, networking, staff training and development, social activities & status, representation & lobbying and articulation & mobilization, while management, technology & knowledge brokering, regulation & legitimization, financing, and policing public policy services are slightly different in each cases. Additionally, a high level of ties with other intermediary organizations was identified in all cases, revealing a complex dynamic of self organizing components that often interact in a collaborative and interdependent way. These findings point to a more in-depth understanding of how innovation intermediaries act within systems to connect components, building multilateral projects that benefit the system as a whole. Also, the detailed information about how these associations contribute to science parks point to a better assessment of the science parks themselves and of how they may impact innovation through the services provided by the intermediaries they are associated with.