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Synthesis and fungitoxicity of aldimines and 4-thiazolidinones derived from 4-bromoaniline

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Abstract

Condensation of 4-bromoaniline with benzaldehyde and substituted benzaldehydes (1-8) in equimolar ratio resulted in the formation of benzal-4-bromoaniline and its C-phenyl derivatives (1a-8a). Addition of thioglycolic acid to 1a-8a yielded the respective 4-thiazolidinone (1b-8b). The synthesized compounds were characterized on the basis of elemental analysis and spectral studies and were screened against five phytopathogenic fungi.

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