Cartilage regeneration and repair is one of the major obstacles to treat arthritic diseases. The members of the bone morphogenetic protein (BMP) family of the transforming growth factor-β (TGFβ) superfamily received a high degree of attention among factors potentially capable of inducing and promoting anabolic processes in articular cartilage [1, 2]. BMPs were first isolated from demineralized bone matrix and shown to induce ectopic bone formation when implanted subcutaneously [3, 4]. The BMP family currently consists of more than 47 related molecules identified in different species [5,6]. Although BMPs were initially found in bone matrix, it has been shown that they are present in most tissues and organs. They are involved in numerous physiological and pathological processes: differentiation, embryogenesis, morphogenesis, skeletal patterning, development, tissue regeneration, organogenesis, apoptosis, etc.