Article

Diuretic studies on lemon grass tea from Cymbopogon citratus (DC) Stapf in rat

Authors:
To read the full-text of this research, you can request a copy directly from the authors.

Abstract

The safety of lemon grass tea prepared from Cymbopogon citratus (DC) Stapf. (lemon grass) was evaluated in rats. The extract was administered for 6 weeks intragastrically and produced no adverse effects after its use. No morphometrical or histological changes were noticed in the vital organs of the test and control animals. Besides no biochemical changes were noticed in the blood and urine of test rats under our experimental conditions. The results were comparable with standard green tea. It was diuretic in action.

No full-text available

Request Full-text Paper PDF

To read the full-text of this research,
you can request a copy directly from the authors.

... Other toxicity studies indicated that citral, which is a major constituent of Cymbopogon citratus, is devoid of major toxicity and carcinogenic potential in both mice and rats [51,52] . According to [53] , the extract administered to rat did not present adverse effects, considering that morphometric and histological alterations were not observed in vital organs, or biochemical alterations in the blood and urine. An infusion of lemongrass given orally to male and pregnant female rats for two months in doses up to 20 times the corresponding human dose did not induce any toxic effects and no external malformations were noted in the offspring [54] . ...
Article
Full-text available
Ectoparasitic skin diseases of domestic ruminants caused by mange mites, lice, fleas, keds and ticks are among the serious diseases causing enormous economic losses to smallholder farmers, the tanning industry and the country as a whole. Infestation with ectoparasites is responsible for blood loss, irritation which results in downgrading and rejection of skins, poor growth, decreased production and reproduction and mortality. Even though ectoparasites of ruminants can be controlled by using synthetic commercial acaricides, their accessibility and affordability to the poor farmers, development of drug resistance and their profound impact on the environment makes them less preferable compared to other alternatives such as medicinal plants. Thus urgent action has to be designed to evaluate acaricidal efficacy of the traditionally used medicinal plants against ectoparasitic skin diseases of domestic ruminants in Ethiopia.
... Lemongrass tea is used as a "sedative" in folk medicine and terpenes such as myrcene may constitute a lead for development of new peripheral analgesics with a profile of action different from that of aspirin-like drugs (Lorenzetti et al, 1991). Mirza et al (2001) reported that lemongrass tea is diuretic in action. ...
Data
Full-text available
Article
Full-text available
The aim of this study was to investigate the effect of drying on quality and sensory attributes of lemon grass (Cymbopogon citratus) tea. Lemongrass (C. citratus) leaves were dried using four different drying methods: sun, solar, oven (40, 50, and 60°C), and microwave (50 W). Teas made from the grass were analyzed for colour, pH and sensory attribute. Data obtained were statistically analyzed using SPSS Version 23 one way analysis of variance and means were compared using Duncan multiple comparison test (p ˂ 0.05). Results obtained indicate that after drying the moisture content were significantly reduced. Ash content results showed no significant difference amongst lemongrass samples dried under difference drying methods. However, there was a significant difference (p < 0.05) in the pH of tea made from the lemongrass dried under different drying methods. Results indicate that drying temperature and time are the main factors affecting the colour of dried lemongrass leaves for tea. There was a significant difference (p < 0.05) in the colour profile of the dried leaves. Sensory evaluation results showed that the colour, aroma, taste, and overall acceptability scores of tea from lemongrass dried with oven at 40°C was highest. The study revealed that oven drying at 40°C for 15 hours was found to be most suitable for drying of lemongrass leaves for tea production in order to retain appreciable sensory attributes.
Article
Three indigenous medicinal plants reported to be diuretic have been selected for the study of trace elements and their possible role in human health. Twelve trace elements (Cu, Zn, Mn, Fe, Cu, Ni, Cd, Pb, Cr, Ag, Na and K) have been detected and estimated in ash of various parts (leaves of Cymbopogon citratus (DC) Stapf., seeds of Raphanus sativus Linn. and corn silk of Zea mays Linn.).
Article
Full-text available
RESUMO: Cymbopogon citratus (DC.) Stapf: composição química e atividades biológicas. Cymbopogon citratus (DC.) Stapf é uma graminea perene, amplamente distribuída no mundo, principalmente em regiões tropicais e savanas. As infusões das folhas são usadas na medicina popular como antimicrobiano, antinflamatório e sedativo. O óleo essencial da folha é usado em indústrias alimentícias, de perfumaria, cosmética e farmacêutica e de fabrico de inseticidas. Os principais constituientes do óleo essencial são citral (mistura dos aldeídos geranial + neral) e terpenos (mirceno -monoterpeno e geraniol -álcool terpênico). Esta revisão apresenta uma ampla descrição dos constituintes químicos e das atividades biológicas, visando ressaltar o potencial desta planta como recurso farmacêutico e agrícola. ABSTRACT: Cymbopogon citratus (DC.) Stapf is a perennial grass that grows spontaneously around the world, mainly in the tropical and savannah regions. Infusions of its leaves are used in traditional medicine as antimicrobial, anti-inflammatory and sedative. The leaf essential oil is used in the food, perfumery, soap, cosmetic, pharmaceutical and insecticide industries. The main constituents of the essential oil are citral (aldehydes geranial + neral) and terpenes (myrcene -monoterpene and geranial -terpenic alcohol). The comprehensive account of the chemical constituents and the biological activities are presented in this review to allow an evaluation of the potential use of this plant either in pharmaceutics or as an agricultural resource.
Article
Full-text available
The composition of the essential oil of Cymbopogon citratus (DC.) STAPF (lemongrass, Graminae) cultivated in Morocco was determined by GC and GC/MS on two different polarities (Carbowax 20M and SE-30) capillary columns. Approximately 89% (34 components) of the essential oil was identified. The mains constituents were geranial (39,8%) and neral (32%).
Article
Hypoglycemic activity of several kinds of Japanese tea was examined and bancha was found to have potential hypoglycemic activity in streptozotocin-induced hyperglycemic and normal rats. One of the active principles was purified by chromatograph on Toyopearl HW-50F and diethylaminoethyl-cellulose and determined to be heteropolysaccharide (T-b) consisting of arabinose, D-ribose and D-glucose (5.1 : 4.7 : 1.7), which gave a molecular weight of approximately 4×10⁴.
Article
Lemon grass (Cymbopogon citratus Stapf) was extracted with 80% ethanol. The extract was not found to be mutagenic in the Salmonella mutation test with or without metabolic activation. However, the extract was found to possess antimutagenic properties towards chemical-induced mutation in Salmonella typhimurium strains TA98 and TA100. Mutagenicity of AFB1, Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2, IQ, MNNG and AF-2, was inhibited by the extract of lemon grass in a dose-dependent manner, but no effect was found on the mutagenic activity of benzo[a]pyrene.
Article
An aqueous extract of Lepidium latifolium L. given orally and intraperitoneally considerably enhanced urinary excretion (UV) in rats with respect to control groups. A slight increase in ion excretion was also observed. Other parameters such as specific gravity, nitrite, pH, glucose, ketone bodies, urobilinogen, and blood were also studied. A good correlation for the dosage rat/man for the aqueous extract was achieved.