Based on analysis of fault activity, linked well survey line along fault strike, fault internal structure and its matching relation with sand-body, and specific reservoir distribution of Tangzhuang-Xiaozhuang area in Huimin depression, hydrocarbon migration along fault strike was studied and the migration pathway was confirmed by geochemistry data. The results show that fault is a complex three-dimensional geological body with certain volume and heterogeneous structures. It is an important gateway for hydrocarbon migration, and there are migration components in vertical, lateral and strike of fault. Hydrocarbon migration styles along fault strike could be divided into migration through transporting ridge in fault and migration through transporting ridge composed by sand-body and fault. In different periods of fault activity, different transporting styles dominate in hydrocarbon migration along fault strike with gradual transition. In fault activity, early stationary and short-term quiescent period, hydrocarbon migration is mainly through transporting ridge in fault, and it is mainly through transporting ridge composed by sand-body and fault in long-term quiescent.