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Pharmacology and Traditional Uses of Mimosa pudica

Authors:
  • Hindustan University / HITS

Abstract

Mimosa belongs to the taxonomic group Magnoliopsida and family Mimosaseae. In Latin it is called as Mimosa pudica Linn. Ayurveda has declared that its root is bitter, acrid, cooling, vulnerary, alexipharmic. It is used in the treatment of leprosy, dysentery, vaginal and uterine complaints, and inflammations, burning sensation, asthma, leucoderma, fatigue and blood diseases. Decoction of root is used as gargle to reduce toothache. It is very useful in diarrhea (athisaara), amoebic dysentery (raktaatisaara), bleeding piles and urinary infections. This review gives a brief compilation of its phytochemical and pharmacological activities.
Available online at www.ijpsdr.com
International Journal of Pharmaceutical Sciences and Drug Research 2013; 5(2): 41-44
41
Review Article ISSN 0975-248X
Pharmacology and Traditional Uses of Mimosa pudica
Baby Joseph*, Jency George, Jeevitha Mohan
Interdisciplinary Research Centre, Department of Biotechnology, Malankara Catholic College, Mariagiri,
Kaliakkavilai, Tamil Nadu, India
ABSTRACT
Mimosa belongs to the taxonomic group Magnoliopsida and family Mimosaseae. In Latin it is called as Mimosa pudica
Linn. Ayurveda has declared that its root is bitter, acrid, cooling, vulnerary, alexipharmic. It is used in the treatment of
leprosy, dysentery, vaginal and uterine complaints, and inflammations, burning sensation, asthma, leucoderma, fatigue and
blood diseases. Decoction of root is used as gargle to reduce toothache. It is very useful in diarrhea (athisaara), amoebic
dysentery (raktaatisaara), bleeding piles and urinary infections. This review gives a brief compilation of its phytochemical
and pharmacological activities.
Keywords: Antiulcer activity, Mimosine, Phytochemistry, Mimosa pudica.
INTRODUCTION
Nature has been a source of medicinal agents for thousands
of years. Various medicinal plants have been used for years
in daily life to treat disease all over the world. [1] Herbal
medicine is based on the premise that plants contain natural
substances that can promote health and alleviate illness. [2-3]
The most important of these biologically active constituents
of plants are alkaloids, flavonoids, tannins and phenolic
compounds. [4] There are many herbs, which are
predominantly used to treat cardiovascular problems, liver
disorders, central nervous system, digestive and metabolic
disorders.
The Mimosa pudica, invites attention of the researchers
worldwide for its pharmacological activities such as anti
diabetic, antitoxin, antihepatotoxin, antioxidant and wound
healing activities. It is reported to contain alkaloid, glycoside,
flavonoid and tannis. It is used in suppresses kapha and pitta
heals wounds, coagulates blood and sexual weakness. [5] All
parts of the tree are considered to possess medicinal
properties and used in the treatment of biliousness, leprosy,
dysentery, vaginal and uterine complaints, inflammations,
burning sensation, fatigue, asthma, leucoderma, blood
diseases. [6] The purpose of this article is to review
phytochemical and pharmacological properties of this
medicinal plant.
Common Names of Mimosa pudica
Mimosa pudica is also known as chuimui [6] or lajwanti in
*Corresponding author: Dr. Baby Joseph,
Professor cum Scientist, Interdisciplinary Research Centre,
Department of Biotechnology, Malankara Catholic College,
Mariagiri, Kaliakkavilai, Tamil Nadu, India; Tel.: +91-
9790403221; E-mail: petercmiscientist@yahoo.co.in
hindi because of its unique property to droop or collapse
when touched and opens up a few minutes later. Its other
names are Betguen Sosa (Guam), Memege (Niue), Mechiuaiu
(Palau), Limemeihr (Pohnpei), Ra Kau Pikikaa (Cook
Islands). The Chinese name for this plant translates to
"shyness grass". [7] Its Sinhala name is Nidikumba, where
'nidi' means 'sleep'. Its Tamil name is Thottal Sinungi, where
'Thottal' means 'touched' and 'Sinungi' means 'little cry'.
Other non-English common names include Makahiya
(Philippines, with maka- meaning "quite" or "tendency to
be", and -hiya meaning "shy", or "shyness"), Mori Vivi
(West Indies). In Urdu it is known as Chui-Mui. In Bengali,
this is known as 'Lojjaboti', the shy virgin. In Indonesia, it is
known as Putri Malu (Shy Princess). In Myanmar (Burma) it
is called 'Hti Ka Yoan' which means "crumbles when
touched". It has been described as “sparshaat sankochataam
yaati punashcha prasruta bhavet” -a plant which folds itself
when touched and spreads its leaves once again after a
while.
Scientific Classification
Kingdom : Plantae
Division : Magnoliophyta
Class : Magnoliopsida
Order : Fabales
Family : Fabaceae
Subfamily : Mimosoideae
Genus : Mimosa
Species : M. pudica
Distribution
Mimosa pudica is native to South America and Central
America. It is regarded as an invasive species in Tanzania,
South Asia, South East Asia and many Pacific Islands. [7] It is
a declared weed in the Northern Territory. [8] Control is
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42
recommended in Queensland. [9 ] It has also been introduced
to Nigeria, Seychelles, Mauritius and East Asia but is not
regarded as invasive in those places. [7]
Fig. 1:
Mimosa pudica
Botanical Description
Mimosa pudica was first formally described by Carl
Linnaeus in Species Plantarum in 1753. Mimosa is usually a
short prickly plant with its branches growing close to ground.
It grows up to a height of about 0.5 m and spreads up to 0.3
m. The stem of mimosa is erect, slender, prickly and well
branched. Leaves are bipinnate [10], fern like and pale green
in colour with a tendency of closing when disturbed. These
are quadri-pinnate, often reddish, leaflets 15 to 25 pairs,
acute, bristly, usually 9 to 12 mm long and 1.5mm wide.
Flowers of this plant are axillary in position and lilac pink in
colour usually occurring in globose heads. Calyxes are
companulate, and petals are crenate towards the base.
Flowering occurs from August to October in Indian
conditions. Fruits of mimosa are pods, 1.5 to 2.5 cm long,
falcate and closely prickly on sutures. [10]
Botanical description of M. pudica
Characters M. pudica
Plant Short prickly branches, hairs glandular
Leaves Bipinnate, sensitive to touch
Flowers
Axillary, globose head, lilac pink in
colour
Stem
Erect, slender, prickly and w
Calyxes Companulate
petals Petals crenate towards base
Pods 1.5 to 2.5 cm long, Closely prickly on
the sutures and falcate
Flowering and
Fruiting time
August to October in Indian conditions
Plant Movement
Mimosa pudica is well known for its rapid plant movement.
In the evening the leaflets will fold together and the whole
leaf droops downward. It then re-opens at sunrise. This type
of motion is termed as nyctinastic movement. The foliage
closes during darkness and reopens in light. [11] The leaves are
drooping because of stimulus, in conditions such as touching,
warming or shaking. The stimulus can be transmitted to
neighbouring leaves. These types of movements are termed
as seismonastic movements. This is due to loss of turgor
pressure. The movement is caused by a rapid loss of pressure
in strategically situated cells that cause the leaves to droop
right before one’s eyes.
Principal Constituents of Mimosa plant
M. pudica contains Mimosine [6, 12], which is a toxic alkaloid.
Adrenalin like substance has been identified in the extract of
its leaves. Some workers have reported the presence of
Crocetin dimethyl Easter in the extract of the plant. Roots
contain tannin up to 10 per cent. Seeds contain a mucilage
which is composed of d-xylose and d-glucuronic acid. The
plant extract contains green yellow fatty oil up to 17 per cent.
The plant is reported to contain tubuline and a new class
phytohormone turgorines is found to be active in the plant.
The periodic leaf movement factors are reportedly the
derivatives of 4-α-(b-D-glucopyranosyl-6-sulphate)gallic
acid. The preliminary phytochemical screening of the M.
pudica leaf extract showed the presence of bioactive
components such as terpenoids, flavonoids, glycosides,
alkaloids, quinines, phenols, tannins, saponins, and
coumarins. [13]
Traditional Uses
Ayurveda has declared that its root is bitter, acrid, cooling,
vulnerary, alexipharmic, and used in the treatment of leprosy,
dysentery, vaginal and uterine complaints, inflammations,
burning sensation, asthma, leucoderma, and fatigue and
blood diseases. Unani Healthcare System its root is resolvent,
alternative, and useful in the treatment of diseases arising
from blood impurities and bile, bilious fevers, piles, jaundice,
and leprosy etc. Decoction of root is used with water to
gargle to reduce toothache. It is very useful in diarrhea
(athisaara), amoebic dysentery (raktaatisaara), bleeding piles
and urinary infections. It arrests bleeding and fastens the
wound healing process. It is mainly used in herbal
preparations for gynecological disorders. It has been said to
have medicinal properties to cure skin diseases. It is also
used in conditions like bronchitis, general weakness and
impotence. It is also used to treat neurological problems. The
content of M. pudica has a capacity of arresting bleeding and
it fastens the process of healing of wounds. It is
recommended in diarrhea, amoebic dysentery and bleeding
piles. It is also used in herbal preparations of gynecological
disorders. Its extract can cure skin diseases. Some herbal
doctors recommend it for bronchitis, general weakness and
impotence. All the five parts of the plant leaves, flowers,
stems, roots, and fruits are used as medicines in the
traditional healthcare systems. In India, different parts of the
plant have been in popular use for treating various ailments
since long. Recent researches show that the extract of this
plant can be used for checking child birth. Some authors have
reported that this herb can replace contraceptive pills if
researches are done properly.
According to different researches done so far, Mimosa
tenuiflora bark is used to relax the mind, and relieve
depression, mental distress, irritability, severe palpitations,
and amnesia. It is a mood enhancer and improves circulation
of the blood. Some believe Mimosa can reduce the onset of
baldness. Due to its ability to promote healthy cell growth,
Tepezcohuite is used in shampoos, creams, capsules, and
soaps. In Ayurvedic and Unani medicine, Mimosa pudica
root is used to treat bilious fevers, piles, jaundice, leprosy,
dysentery, vaginal and uterine complaints, inflammations,
burning sensation, fatigue, asthma, leucoderma, and blood
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43
diseases. In Western medicine, Mimosa root is used for
treating insomnia, irritability, premenstrual syndrome (PMS),
menorrhagia, hemorrhoids, skin wounds, and diarrhea. It is
also used to treat whooping cough and fevers in children, and
there is some evidence to suggest that Mimosa is effective in
relieving the symptoms of rheumatoid arthritis. All parts of
the Mimosa plant are reportedly toxic if taken directly. Its
consumption is not recommended to pregnant or nursing
ladies. Due to these reports, it seems to be best to consult a
physician before using Mimosa internally. Researches
regarding safety in young children or those with severe liver
or kidney disease have not been found. [14]
Pharmacological Activities
Wound healing activity
The M. pudica shoot methanolic extract, M. pudica root
methanolic extract showed very good wound healing activity.
[15] The methanolic extract exhibited good wound healing
activity probably due to presence of phenols constituents. [16-
18]
Antimicrobial Activity
The antimicrobial activity of methanolic extract of Mimosa
was tested against Aspergillus fumigatus, Citrobacter
divergens and Klebsiella pneumonia at different
concentrations of 50, 100 and 200μg/disc. The antimicrobial
activity was attributed to the presence of bioactive
constituents like terpenoids, flavonoids, glycosides,
alkaloids, quinines, phenols, tannins, saponins and coumarin.
[13]
Analgesic and anti-inflammatory activity
The ethanolic extract of the leaves of M. pudica at the doses
of 200 and 400 mg/kg was tested for anti-inflammatory and
analgesic activity. The extract produced dose dependent and
significant inhibition of carrageenan induced paw oedema.
The analgesic activity was found to be more significant on
the acetic acid induced writhing model than the tail flick
model. The presence of flavonoids in the ethanolic extract
may be contributory to its analgesic and anti-inflammatory
activity. [19]
Anticonvulsant
The decoction of M. pudica leaves were given
intraperitoneally at dose of 1000-4000 mg/kg which
protected mice against pentylentetrazol and strychnine-
induced seizures. M. pudica had no effect against picrotoxin-
induced seizures. It also antagonized N-methyl-D-aspartate-
induced turning behavior. [20]
Antidiarrhoeal activity
Diarrhea is the condition of having three or more loose or
liquid bowel movements per day. The anti-diarrhoeal
potential of the ethanolic extract of leaves of M. pudica has
been evaluated using several experimental models in Wistar
albino rats. The ethanolic extract inhibited castor oil induced
diarrhoea and PGE2induced enteropooling in rats and has
also reduced gastrointestinal motility after charcoal meal
administration. The ethanolic extract at 200 and 400 mg/kg
was showed significantly inhibited diarrhoea. The anti-
diarrhoeal property may be related to the tannin and
flavonoids present in the extract. [21]
Antifertility activity
M. pudica root extract, when administered orally at a dose of
300 mg/kg body weight/day, prolonged the length of the
estrous cycle with significant increase in the duration of the
diestrous phase and reduced the number of litters in albino
mice. The number of litters was increased in the
posttreatment period. The analysis of the principal hormones
(Luteinizing hormone, Follicle-stimulating hormone,
prolactin, estradiol and progesterone) involved in the
regulation of the estrous cycle showed that the root extract
altered gonadotropin release and estradiol secretion. [22 ]
Anti oxidant activity
The methanol crude extract of the aerial part of M. pudica
was screened in vitro for antioxidant activity using the 1, 1-
diphenyl-2-picrylhydrazyl-hydrate (DPPH) free radical
scavenging assay. The methanol crude extract of the aerial
part showed moderate antioxidant activity (IC50
296.92μg/ml) compared to ascorbic acid (IC50 131.29μg/ml)
suggesting presence of biologically active constituents in the
methanolic extract of M. pudica. [23]
Antimalarial activity
The ethanolic extract of M. pudica leaves was investigated
for antimalarial activity against Plasmodium berghei
infections in mice. The extract of P. niruri and M. pudica leaf
demonstrated significant antiplasmodial activity in all the
three models of the antimalarial evaluations. Phytochemical
screening revealed the presence of some vital antiplasmodial
constituents such as terpenoids, flavonoids and alkaloids. The
leaf extract of P. niruri and M. pudica possesses antimalarial
activity. [24]
Anti-hepatotoxic activity
The ethanol extract of M. pudica leaves was evaluated for its
hepatoprotective against carbon tetrachloride (CCl4)-induced
liver damage, in Wistar albino rats. The ethanol extract of M.
pudica (Mimosaceae) leaves (200 mg/kg body weight, p.o.)
was administered to the experimental rats for 14 days. The
hepatoprotective activity was assessed using various serum
biochemical parameters as glutamate oxaloacetate
transaminase (SGOT), glutamate pyruvate transaminase
(SGPT), alkaline phosphatase (ALP), bilirubin, and total
proteins. Malondialdehyde level as well as the activities of
superoxide dismutase, reduced glutathione and catalase was
determined to explain the possible mechanism of activity.
The substantially elevated levels of serum SGOT, SGPT,
ALP and total bilirubin, due to CCl4treatment, were restored
towards near normal by M. pudica (Mimosaceae), in a dose.
Reduced enzymatic and non-enzymatic antioxidant levels
and elevated lipid peroxide levels were restored towards near
normal, by administration of M. pudica. The ethanol extract
of M. pudica afforded significant dose dependent
hepatoprotective an antioxidant effects in CCl4-induced
hepatic damage. [25]
Antihelminthes activity
The present study was undertaken to evaluate anthelmintic
activity of different extracts of seeds of M. pudica. The
different successive extracts namely petroleum ether, ethanol
and water using Pheretima posthuma as a test worm to the
different concentrations (100, 200, 500 mg/kg) were tested
for bioassay which involved determination of paralysis and
time of death of the worms. Crude alcoholic extract and
aqueous extracts significantly demonstrated paralysis and
also caused death of worms in dose dependent manner as
compared to standard reference albendazole. While Pet.
Ether extracts shows weak anthelmintic effect compared to
standard, ethanol and aqueous extracts. [26]
Antihyperglycemic activity
Chloroform extract of M. pudica leaves has been screened for
its hypolipidemic activity against atherogenic diet in wistar
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44
albino rats and serum levels of various biochemical
parameters such as total cholesterol, triglycerides, high-
density lipoprotein, very low-density lipoprotein and low-
density lipoprotein cholesterol were determined. Atherogenic
index shows the measure of the atherogenic potential of the
drugs. Chloroform extract showed significant hyperlipidemic
effect by lowering the serum levels of biochemical
parameters such as significant reduction in the level of serum
cholesterol, triglyceride, LDL, VLDL and increase in HDL
level which was similar to the standard drug Atorvastatin.
Chloroform extract exhibited significant atherogenic index
and percentage protection against hyperlipidemia.
The overall experimental results suggests that the
biologically active phytoconstituents such as flavonoids,
glycosides alkaloids present in the chloroform extract of M.
pudica, may be responsible for the significant hypolipidemic
activity and the results justify the use of M. pudica as a
significant hypolipidemic agent. [27]
Antiulcer activity
Antiulcer potential of ethanolic extract of M. pudica leaves
was evaluated by pylorus ligation, aspirin and ethanol
induced ulcer models. The ethanolic extract of the leaves of
M. pudica was given by oral route at a dose of 100 mg/kg
b.w. Ethanolic extract of M. pudica, dose dependently
reduce, the total acidity, ulcer index, and an increase in pH of
gastric juice in pylorus ligated ulcer model. [28]
Antivenom activity
Aqueous extract of dried roots of M. pudica was tested for
inhibitory activity on lethality, phospholipase activity, edema
forming activity, fibrinolytic activity and hemorrhagic
activity of Naja naja and Bangarus caerulus venoms. The
aqueous extract displayed a significant inhibitory effect on
the lethality, phospholipase activity, edema forming activity,
fibrinolytic activity and hemorrhagic activity. About 0.14 mg
and 0.16 mg of M. pudica extracts were able to completely
neutralize the lethal activity of 2LD50 of Naja naja and
Bangarus caerulus venoms respectively. [14]
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... Mimosa pudica has been widely studied due to its potential pharmacological properties, including antidiabetic, antioxidant, antitoxin, wound healing, and antihepatotoxic effects (Joseph et al., 2013). The β-cell differentiated phenotype is maintained by steady physiological stimulation of glucose, and glucotoxicity is defined as toxic or deleterious impacts on the β-cell phenotype in extended or persistent contact with high glucose levels in vitro as well as in vivo studies. ...
... The dried powder of leaf is used in the treatment of irritable bowel syndrome.Leaves are reported to be effective against piles, kidney troubles, muscular pain, ulcers, and wounds. The pounded leaves are used as an external application to boils and carbuncles.13 Withania somnifer a Linn. ...
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Chapter
Indigenous knowledge gained by the local people or tribes of a specific region over a long period will be of immense significance. An attempt has been made to document application of common wild as well as cultivated medicinal plant species in the southwest coast of India. This study emphasizes vernacular names of medicinal plant species, flowering/fruiting season, parts of plant used and specific ethnic practices (product, route and remedy). Ethnic particulars of 28 plant species (9 trees, 8 shrubs, 9 herbs, 1 grass and 1 climber) are given, among them six plants are also predominantly used for edible purpose, 28 plants for medicinal purpose and 13 plants serve as nutraceuticals. The indigenous medicinal preparations mainly include decoction, paste, extract, oil, powder and juice. The ethnic nutraceutical delicacies mainly include soup, starter, snack and porridge. Some plant parts are preserved for use during offseason. Major routes of administration of ethnic product are oral, nasal and topical. Several ethnic knowledge-based courtiers have strong tradition to use specific plant species to fight against protein energy malnutrition as well as lifestyle diseases like cancers, diabetes and cardiovascular. Keywords: Diversity, Ethnic medicine, Nutraceutical value, Remedial measures, Traditional knowledge
... It is commonly known as "touch me not", "sensitive plants" and "shy plant" in English language or "touch and die" among the locals in Nigeria. The plant has been demonstrated to have other medicinal properties such as antidepressant, hypoglycaemic, wound healing, anticonvulsant properties [5]. Mimosa pudica has also been successfully used in the treatment of diarrhea, dysentery and urogenital infections in China, Phillipines, South America and India [6]. ...
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Purpose: To investigate the toxicity, clinical outcome and anthelmintic effects of M. pudica in vitro and in vivo.Methods: Dried leaves of M. pudica were extracted using 70 % methanol cold maceration method. Acute toxicity inquiry was evaluated using Lorke’s method. Anthelmintic effects were investigated in vitro using the egg hatch assay and in vivo using Heligmosomoides bakeri experimentally infected adult albino mice. Coprological and haematological parameters were recorded during the experiment while the serological analysis and post mortem worm burden were assessed at the conclusion of the research.Results: No mortality was recorded in oral acute toxicity test up to a dose of 5000 mg/kg. A probit-log analysis of the percentage egg hatch of the extract and albendazole gave lethal concentration 50 (LC50) values of 1.160 and -1.042, respectively. A reduction in worm count was observed in all the extracttreated groups post mortem, with the maximum extract group having the least worm count (p < 0.05). Treatment with extract resulted in improvement in the haematological parameters. Serum chemistry revealed no significant differences (p > 0.05) in alanine aminotransferase and blood urea nitrogen in all groups. However, a dose-dependent increases in the total protein and albumin was observed.Conclusion: These results show that although M. pudica has weak anthelmintic effects compared to albendazole (standard anthelmintic), in vivo and in vitro, at the doses used in this study, nonetheless, it reduces worm burden and improves haematologic parameters, serum total protein, albumin and overall weight gain of the treated mice. Thus, increased doses may be effective in anthelmintic chemotherapy. Keywords: Mimosa pudica, Anthelmintic, Toxicity, Heligmosomoides bakeri, Ethnoveterinary medicine, Anthelmintic
... There are various herbs, which used to treat cardiovascular problems, digestive and liver disorder metabolic disorders and central nervous system. The herbal remedies consist of various biological active constituents [5]. In India, Ayurveda is being practiced for nearly 5000 years. ...
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Background: Medicinal plant and herbs used for anti-ulcer activity in the form of extract. Many studies are done for confirmation the extract of the medicinal plant helps to relieve stomach pain, ulcer recurrence and beneficial in the treatment for ulcer disease. An herbal plant uses different parts for treating various diseases such a seed, flowers, leaves, fruits, roots, berries and bark. Objective: To perform the standardization, pharmacognostic evaluation, physicochemical phytochemical activities of ethanolic polyherbal for the beneficial effect could be utilized in the treatment of the peptic-ulcer diseases. Method: The extract prepared of polyherbal by using ethanol as solvent, done standardization by the standard method, pharmacognostic evaluation, physicochemical evaluation by various methods, macroscopic and microscopic character of the polyherbal plant were performed at PSIT laboratory. Result and Conclusion: plant studies can be used in diseases for identification and performed the pharmacognostic evaluation of polyherbal plants. Therefore, the report introduced of polyherbal powder by studies of macroscopic character by indicating thickness, length and Physiochemical parameters of polyherbal done by the various standard method were observed. Presence of chemical constituents in the polyherbal extract by studies of phytochemical screening methods. Research works need to be done for therapeutic and commercial uses.
... It contains tannins, flavonoids, glycosides, and alkaloids [96,97]. It is used in blood diseases, leucoderma [98], asthma [99], leprosy [100], burning sensation [96], uterine and vaginal complaints [101], jaundice [102], inflammation [103] and piles [104]. It is an antidepressant [105,106], antitoxin [107], antioxidant [108], hypolipidemic [109], antihepatotoxic, anti-diabetic [110] and anticonvulsant [111]. ...
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Exploration of new drugs targeting anxiety treatment is a major concern worldwide. Medicinal plants are being used as a potential source of novel drugs for anxiety disorders. The objective of this review is to provide information about the healing outcomes of anxiety treatment with natural products. Valeriana officinalis, Citrus aurantium, Commelina benghalensis, Achyranthes aspera, Mimosa pudica, Achillea millefolium, Nymphaea alba, Leonurus cardiac, Camellia sinensis, Turnera aphrodisiaca, Crataegus oxyacantha and Piper methysticum showed promising effects on anxiety in animal models. In clinical studies, passion flower, kava, valerian, St John's wort, and ashwagandha showed the most positive results. More studies are needed for the exploration of the anti-anxiety of medicinal plants. In drugs derived from natural sources have explored many components that are playing an essential role in curing anxiety disorders and associated complications.
... Silk road, an expression of green architecture "sustainability and confilict with climate ... [2] Optimization of window proportions with an approach to reducing energy consumption ... [3] Evaluation of renovation measures for urban deteriorated fabrics in Iran (in Comparison to global renovation experiences) in line with the objectives of sustainable … [4] Determining the most efficient window-to-wall ratio in southern façade of educational ... [5] The significance of natural components of Quranic life in Islamic-Iranian architecture ... [6] Horizontal and vertical movable drop-down shades performance in ... Mimosa pudica Linn-a shyness princess: A review of its plant movement ... [26] Mimosa-A brief ... [27] Electrical experiments with plants that count and ... [28] Mimosa pudica, dionaea muscipula and … [29] A methodology for transferring principles of plant movements to elastic systems in ... [30] Parametric algorithms for unity of architecture and ... [31] Pharmacology and traditional uses of Mimosa … Aims Fixed vertical and horizontal canopies that are used in buildings give a low level of clean and inexpensive energy. Therefore, modern technology should use in constructing new buildings in order to have maximum use of this blessing. ...
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چکیده اهداف: سایبانهای عمودی و افقی ثابت به کاربردهشده در بناها از لحاظ بهره بردن مناسب از تابش خورشید، دارای میزان پایینی از استحصال انرژی پاک و ارزان هستند. بنابراین برای رفع مانع استفاده حداکثری از این نعمت خدادادی باید بناهای جدید را به سوی تکنولوژی روز هدایت کرد. یکی از این موارد، استفاده از سایبان های متحرک در نما است که علاوه بر بهره جویی از نور خورشید، موجب ایجاد نماهایی با طراحی دینامیکی میشود. هدف از انجام پژوهش حاضر، ارایه مدل پوسته هوشمند متحرک در راستای بهینه سازی مصرف انرژی با الهام از الگوریتم حرکتی گیاه قهر و آشتی است. مواد و روشها: این پژوهش از نوع کمی و مدلسازی- شبیه سازی است که مدلسازی یک پوسته متحرک در نرم افزار راینو ۶ و پلاگین گرس هاپر و تحلیل های اقلیمی توسط پلاگین لیدیباگ انجام شده است. این پوسته در جبهه جنوبی یک بنا با موقعیت اقلیمی شیراز مورد تحلیل قرار گرفته است. یافته ها: در پژوهش حاضر، سعی بر آن شد تا با هوشمندسازی نما بتوان سایبان هایی با تغییر زاویه یک درجه ای در هر یک از پنلها ایجاد کرد تا علاوه بر فرم زیبایی شناسانه بتوان به عملکرد بهتری دست یافت. میزان تابش دریافتی ۵۰ کیلووات ساعت بر مترمربع است. در نهایت / در این تحلیل بین صفر تا ۱۶ جدولی از تحلیل انرژی پوسته متحرک از ساعت ۶ تا ۱۹ در ماه مرداد و اقلیم شهر شیراز ارایه شده است. نتیجه گیری: از پوسته هوشمند مدلشده میتوان در جهت بهینه سازی مصرف انرژی متناسب با اقلیم شیراز به عنوان سایبان متحرک به ره گرفت. کلیدواژه ها: پوسته متحرک، هوشمندسازی، انرژی، الگوریتم حرکتی، گیاه قهر و آشتی
... The present study showed that people in N. Mimosa pudica L. (Figure 1) is one of the widely used medicinal plants and claimed to have high ayurvedic properties to treat different types of diseases. 5 The same ethno-botanical used of M. pudica in jaundice is also reported from central India. 6 Some research also proved that this plant has high antimicrobial properties. ...
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Medicinal plants are the source of therapeutic agents in traditional medicines. The present study investigated Mizo traditional medicinal plants commonly used and available at N. Mualcheng, a village in Mizoram, India. The most important plants in terms of usage and availability as 10 species belonging to 9 families, of which Asteraceae contributes two species (such as Blumea lanceolaria, Acmella sp.), while Fabaceae, Acanthaceae, Costaceae, Orobanchaceae, Proteaceae, Elaeagnaceae, Smilacaceae and Plantaginaceae contribute one species each such as Mimosa pudica, Thunbergia grandiflora, Chamaecostus cuspidatus, Aeginetia indica, Helicia robusta, Elaeagnus caudata, Smilax perfoliata and Plantago asiatica respectively. An important feature of these medicinal plants is that some of them are used for complex diseases including kidney problem, gastric ulcer and diabetes mellitus.
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Gums are carbohydrate biomolecules that have the potential to bind water and form gels. Gums are regularly linked with proteins and minerals in their construction. Gums have several forms, such as mucilage gums, seed gums, exudate gums, etc. Plant gums are one of the most important gums because of their bioavailability. Plant-derived gums have been used by humans since ancient times for numerous applications. The main features that make them appropriate for use in different applications are high stabilization, viscosity, adhesive property, emulsification action, and surface-active activity. In many pharmaceutical formulations, plant-based gums and mucilages are the key ingredients due to their bioavailability, widespread accessibility, non-toxicity, and reasonable prices. These compete with many polymeric materials for use as different pharmaceuticals in today’s time and have created a significant achievement from being an excipient to innovative drug carriers. In particular, scientists and pharmacy industries around the world have been drawn to uncover the secret potential of plant-based gums and mucilages through a deeper understanding of their physicochemical characteristics and the development of safety profile information. This innovative unique class of drug products, useful in advanced drug delivery applications, gene therapy, and biosynthesis, has been developed by modification of plant-based gums and mucilages. In this review, both fundamental and novel medicinal aspects of plant-based gums and mucilages, along with their capacity for pharmacology and nanomedicine, were demonstrated.
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The ethanolic extract of Phyllanthus niruri and Mimosa pudica leaves was investigated for antimalarial activity against Plasmodium berghei infections in mice. The median lethal dose was determined to ascertain the safety of the extract in mice. The antimalarial activities during early and established infections were evaluated. Phytochemical screening was also investigated to elucidate the possible mechanism of the antimalarial properties. The extract of P.niruri and M.pudica leaf demonstrated significant antiplasmodial activity in all the three models of the antimalarial evaluations. Phytochemical screening revealed the presence of some vital antiplasmodial constituents such as terpenoids ,flavonoids and alkaloids. The leaf extract of P.niruri and M.pudica thus possesses antimalarial activity, which explains the rational usage of this plant in traditional medicine.
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The petroleum ether, chloroform and methanol crude extracts of the two different plant parts (aerial part and root) of Mimosa pudica (Mimosaceae) were screened in vitro for cytotoxicity studies by brine shrimp lethality bioassay and antimicrobial screening by disc diffusion method. The methanol crude extract of the aerial part was screened in vitro for antioxidant activity using the 1, 1-diphenyl-2-picrylhydrazyl-hydrate (DPPH) free radical scavenging assay. The petroleum ether and methanol crude extracts of the root showed potential cytotoxic activities (LC50 0.05 μg/ml and 0.035 μg/ml respectively) whereas the other extractives showed poor cytotoxicity. All the crude extracts showed poor activity or inactivity against the test microorganisms. On the other hand, the methanol crude extract of the aerial part showed moderate antioxidant activity (IC50 296.92 μg/ml) compared to ascorbic acid(IC50131.29 μg/ml). The overall experimental results suggest the biologically active constituents present in the methanolic extract of Mimosa pudica and justify its use in folkloric remedies. Key Words: Mimosa pudica, Mimosaceae, Cytotoxicity, Antimicrobial, DPPH, Antioxidant.
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Objective To evaluate the preliminary phytochemical screening of the flower extracts of Rhododendron arboreum (R. arboreum) Sm. ssp. nilagiricum (Zenker) Tagg.Methods The preliminary phytochemical screening was performed by the standard methods as described by Harborne.ResultsThe phytochemical analysis carried out on the flowers of R. arboreum Sm. ssp. nilagiricum (Zenker) Tagg showed the presence of phenols, saponins, steroids, tannin, xanthoprotein and coumarin.Conclusions The present study suggested that the flower extracts of R. arboreum Sm. ssp. nilagiricum (Zenker) Tagg possess significant phytochemical constituents and it can be used as antimicrobial agents against clinically isolated pathogens.
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The study was carried out to identify through scientific methods the active ingredients and the pharmacological activities of the shoot and root extracts of Mimosa pudica Linn.The Mimosa pudica shoot methanolic extract (MSME), Mimosa pudica root methanolic extract (MRME) showed very good wound healing activity when compared to the standard drug Gentamicin. Whereas Mimosa pudica root Chloroform extract (MRCE) showed negative result. The isolated compounds were characterized by instrumental analysis, UV and IR.
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Mimosa pudica Lin., known as chue Mue, is a stout straggling prostrate shrubby plant, with spinous stipules and globose pinkish flower heads, and grows as weed in almost all parts of the country. It is traditionally used for its various properties and hence in the present study, chloroform extract of Mimosa pudica leaves has been screened for its hypolipidemic activity. Hypolipidemic activity is screened by inducing hyperlipidemia with the help of atherogenic diet in wistar albino rats and serum levels of various biochemical parameters such as total cholesterol, triglycerides, LDL, VLDL and HDL cholesterol were determined. Atherogenic index shows the measure of the athero-genic potential of the drugs. Chloroform extract showed significant (p < 0.05) hypolipidemic effect by lowering the serum levels of biochemical parameters such as significant reduction in the level of serum cholesterol, triglyceride, LDL, VLDL and increase in HDL level which was similar to the standard drug Atorvastatin. Chloroform extract exhibited significant atherogenic index and percentage protection against hyperlipidemia. These biochemical observations were in turn confirmed by histopathological examinations of aorta, liver and kidney sections and are comparable with the standard hypolipidemic drug Atorvastatin. Preliminary phytochemical analysis revealed the presence of phytoconstituents such as steroids, flavonoids, glycosides, alkaloids, phenolic compounds which is further confirmed by the thin layer chromatography, High Performance Thin Layer Chromatography (HPTLC). The overall experimental results suggests that the biologically active phytoconstituents such as flavonoids, glycosides alkaloids present in the chloroform extract of Mimosa pudica, may be responsible for the significant hypolipidemic activity and the results justify the use of Mimosa pudica as a significant hypolipidemic agent.
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To assess antifungal activity of Ocimum sanctum leaves against dermatophytic fungi. Antifungal activity of Ocimum sanctum leaves was measured by 38 A NCCLS method. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and fractions of Ocimum sanctum leaves were also determined. Ocimum sanctum leaves possessed antifungal activity against clinically isolated dermatophytes at the concentration of 200 μg/mL. MIC and MFC were high with water fraction (200 μg/mL) against dermatophytic fungi used. Ocimum sanctum has antifungal activity, and the leaf extracts may be a useful source for dermatophytic infections.
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Although about 8000 species of plants 1 are estimated to be used in human and animal health care and over 10,000 herbal drug formulations have been recorded in codified medical texts of Ayurveda, the pharma-ceutical industries are largely based on about 400 plant species. Though accurate and updated data on the requirement of total quantity and quality of crude drug is not available, conservative estimates put the economic value of medicinal plant related trade in India to the order of Rs.1000 crores / year 2 and the world trade over U.S. $ 60 billion. The only male specific contraceptive methods currently available are withdrawal, condoms and vasectomy. As concerns regarding side effects and convenience of these existing methods prevent their universal acceptance 3-4 . The epididymis plays an important role in sperm development and sperm maturation is dependent on the unique luminal environment of the epididymis including specific proteins synthesized and secreted by the epididymal epithelium 5-6 . The research in to the efficacy of herbs used in traditional veterinary practice would be useful in establishing standard dosages for herbal preparations and to investigate their toxicity 7 .The studies on the male antifertility effects of various medicinal plants have aroused much interest 8-11 .
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Mimosa pudica (common sensitive plant) is a problematic weed in many crops in tropical countries. Eight experiments were conducted to determine the effects of light, seed scarification, temperature, salt and osmotic stress, pH, burial depth, and rice residue on the germination, seedling emergence, and dormancy of M. pudica seeds. Scarification released the seeds from dormancy and stimulated germination, though the germination of the scarified seeds was not influenced by light. The scarification results indicate that a hard seed coat is the primary mechanism that restricts germination. The germination increased markedly with the exposure to high temperature “pretreatment” (e.g. 150°C), which was achieved by placing non-scarified seeds in an oven for 5 min followed by incubation at 35/25°C day/night temperatures for 14 days. The germination of the scarified seeds was tolerant of salt and osmotic stress, as some seeds germinated even at 250 mmol L−1 NaCl (23%) and at an osmotic potential of −0.8 MPa (5%). The germination of the scarified seeds was >74% over a pH range of 5–10. The seedling emergence of the scarified seeds was 73–88% at depths of 0–2 cm and it gradually decreased with an increasing depth, with no seedling emergence at the 8 cm depth. The rice residue applied to the soil surface at rates of ≤6 t ha−1 did not influence the seedling emergence and dry weight. The information gained from this study identifies some of the factors that facilitate M. pudica becoming a widespread weed in the humid tropics and might help in developing components of integrated weed management practises to control this weed.