A region of 1 000 km2 in Enshi, Hubei Province is chosen as the typical study area, and its historical landslide data are comprehensively analyzed in this paper. The strata in the study area are divided into three types including high, middle and low susceptible petrofabrics according to the relationship between local landslide formation and lithology. The scatter diagrams about effective rainfall intensity and critical duration are obtained based on rainfall monitoring data and historical information of landslides in each petrofabric. Thus effective rainfall intensity thresholds are determined and landslide hazard warning model of the study area is suggested. In this study, landslide prediction evaluating system is firstly established based on data of sample area, and then landslide susceptibility distribution map is obtained by using GIS. According to Different Susceptible Petrofabric-Effective Rainfall Intensity Models, the landslide hazard warning is realized by overlaying landslide susceptibility distribution map and rainfall risk grade distribution results. Results show that the hazard warning results fit well with the actual situation. Thus, the warning model is verified to be effective, accurate and comprehensive to provide scientific evidence for preventing and reducing disasters.