We present a study designed to evaluate the efficacy of the SilkPeel system in the treatment of erythematotelangiectatic and papulopustular rosacea. The SilkPeel system is an innovative form of microdermabrasion that exfoliates uniformly and simultaneously allows surface penetration of topical infusion agents, which optimizes therapy while maintaining structural integrity. Thirty qualified patients with erythematotelangiectatic or papulopustular rosacea as defined by the National Rosacea Society underwent SilkPeel treatments bimonthly for 12 weeks. Significant clinical reductions in erythema, papules, and pustules were noted as early as week 4 for all patients (P<.03).