The isolation effect is the finding that memory is improved for items that are distinctive. The isolation effect has led advertisers to suggest that their advertisements should be designed to "stand out" from other advertisements. The current study examined semantic and physical isolation effects for print advertisements. Participants viewed a slideshow containing four advertisements for trashcans. Each advertisement contained a different brand name and feature for the trashcan pictured in the advertisement. In Experiment 1, one of the four advertisements included a product feature rated as highly distinctive (semantic isolate) relative to the product features appearing in the other advertisements. The isolated advertisement in Experiment 2 included a product feature of a different font size and color (physical isolate) than the product features appearing in the other advertisements. Participants were tested on the brand names and features from the advertisements. Unlike previous experiments on isolation effects in advertising, participants were required to remember which feature was presented with which brand. Participants demonstrated an isolation effect, with better recall of the features from the distinctive advertisements than the regular advertisements. This benefit, however, did not reliably extend to memory for the brand names associated with the isolate. These findings demonstrate that the robust nature of the isolation effect is not limited to laboratory settings; rather, the effect is more generalizable and occurs in real-world situations as well.