ArticlePDF Available

Knowledge representation and care planning for population health management

Authors:

Abstract and Figures

The traditional organizing principles of medical knowledge may be insufficient to allow for problem representations that are relevant to solution development in emerging models of care such as population health management. Operational classification and central management of clinical and quality objectives and associated strategies will allow for productive innovation in care design and better support goal-directed collaboration among patients and their health resource communities.
Content may be subject to copyright.
126 www.greenbranch.com | 800-933-3711
PRACTICE MANAGEMENT
In a 2006 article in the New England Journal of Medicine,
“Educational Strategies to Promote Clinical Reasoning,”
Bowen notes that the organizing principles of medical
knowledge may have unfavorable eects on the capac-
ity to apply that knowledge in problem solving1; she further
notes that such curriculum-driven structure may limit the
development of problem representations that incorporate
the necessary complexity and context to support adequate
clinical solution development.2 ese insights have addi-
tional and important implications for the new competen-
cies required by the emerging operating model for care
delivery now generally referred to as “population health
management.”
POPULATION HEALTH MANAGEMENT
Population health management shifts the focus from caring
for patients who self-select for care to taking on transcendent
responsibility for the health status of a cohort or population
of patients, and has come to be associated with evolutionary
trends in payment or compensation for healthcare services
known variously as “accountable care” or “value-based
care.” e goal of value-based care is to deliver high-level
quality-related performance across a population or cohort
of patients using the lowest levels of resources and services
required to eectively reach those quality goals.3
Under value-based care, professional and provider sys-
tem compensation is based not on fees for specic services
provided to individual patients, but on the “accounting”
of the system-level performance toward population level
goals for clinical quality and resource utilization, and set by
the value (economic and otherwise) associated with those
goals (e.g., reducing predicted primary hospitalization
rates by closing evidence-based gaps in care).
Population management is a form of systems-based
practice and requires implementing and mastering an
operating manual that is separate and distinct from
traditional care delivery,4 including a specialized infra-
structure with its own functional requirements and an
associated set of operating capabilities. Although analyt-
ics are often considered the foundation of population
management, improving both the quality of care and the
quality of health of target populations requires new forms
of interaction design and goal-directed collaboration
within and between the systems—human, information,
and environmental—that make up the patient’s health
resource community.
We have observed a pattern in health systems and phy-
sician networks at various stages of the evolution toward
value-based population health management in which the
traditional organizing principles of care planning limit
the capacity of these organizations to develop problem
representations that are appropriate and relevant to the
population management operating model, subsequently
impeding their ability to envision models of care delivery
that extend beyond traditional models of medical practice.
Knowledge Representation and
Care Planning for Population Health
Management
Steven Merahn, MD*
The traditional organizing principles of medical knowledge may be insufcient to
allow for problem representations that are relevant to solution development in
emerging models of care such as population health management. Operational
classication and central management of clinical and quality objectives and as-
sociated strategies will allow for productive innovation in care design and better
support goal-directed collaboration among patients and their health resource
communities.
KEY WORDS: Care plan; quality measures; population health; accountable care; value-
based care.
*Chief Medical Ofcer, US Medical
Management, 500 Kirts Blvd., Troy, MI
48084; phone: 917-689-8954; e-mail:
smerahn@usmmllc.com.
Copyright © 2015 by
Greenbranch Publishing LLC.
www.greenbranch.com
| 800-933-3711
Merahn | Knowledge Representation and Care Planning 127
CLINICAL STRATEGIES AND
CARE PLANNING
Traditionally, the clinical strategies and associated goals
for any one patient were a responsibility distributed among
all of a patient’s providers. This often resulted in lack of
sharing of resources and knowledge, redundancies in
tests, and, sometimes, adverse events due to conicts in
treatment strategies.5 e movement toward the patient-
centered medical home (PCMH) model resulted from the
desire to create a centralized point of management for the
patient’s diverse care plans in order to coordinate care,
identify potential conicts, reduce redundancies, and im-
prove communication.6
In population health, the care plan is the framework for
establishing specic and measurable objectives for clinical,
quality, operational, and outcomes-related aspects of an
individual’s health. In practice, however, the frameworks
for care planning commonly used under PCMH and popu-
lation health are almost exclusively dened by condition,
professional discipline, or patterns of utilization, restricting
the capacity of organizations to consider alternative care
delivery models.
is issue has historical roots. In 1983, Dr. Robert Gor-
don, then Special Assistant to the Director of the National
Institutes of Health, wrote a brief but breakthrough report
critiquing the traditional approach of classifying chronic
illness prevention strategies based on “origins of disease”
and proposing a new framework for “operational classica-
tion” of patient-focused clinical strategies.7
Gordon sought to dene prevention strategies by their
predictable outcomes, targeted to those “for whom the
measure is advisable on a cost-benet basis.” Although his
approach generated some interest within the substance
abuse community,8 these prescient recommendations
were not widely adopted by or socialized in mainstream
medicine.
The core of the Gordon classification describes three
categories of prevention:
Universal measures, recommended for essentially
everyone;
Selective measures, advisable for population subgroups
distinguished by age, sex, occupation, or other evident
characteristics; and
Indicated measures—those that should be applied
only in the presence of a demonstrable condition that
identies the individual as being at higher than average
risk for the future development of a related or comorbid
disease (or event).
In the context of current evolutionary trends in health-
care delivery, the Gordon classication could be consid-
ered the foundation of an approach to transforming clinical
objectives into a rational operational classication scheme,
and is presented here as a universal framework for care
planning in population health management.
THE GORDON CARE PLAN
FRAMEWORK
We congured the Gordon classication into a care plan
framework reecting a spectrum of operational and clinical
goals associated with population management initiatives,
expanded to include wellness/lifestyle objectives at one
end, and prognosis-based compassionate care at the other
(Table 1).
In its practical application, the revised Gordon classi-
cation care plan framework (Gordon Care Plan) recatego-
rizes and aggregates the judgments and recommendations
of all the human and information systems that participate
in a patient’s health resource community. This creates
a continuously updated central repository— the single
“source of truth”— and performance driver shared across
all members of a patient’s health resource community.
Organizations can then determine the most ecient meth-
ods to achieve progress toward goal; responsibility for goal
achievement can be assigned or distributed among the
patient’s resource community.
Given the population-level obligations of health systems
under value-based care, the potential objectives of any
single care plan will fall into one of two categories: system-
driven objectives and person-driven objectives.
System-Driven Objectives
System-driven objectives are those elements of account-
ability between the provider system and those contracting
for care; most system-driven objectives align with clinical/
quality needs of patients but may include operational or
utilization-related objectives as well as qualitative mea-
sures associated with patient experience management
(e.g., physician communication skills, patient satisfaction).
In population management, the provider system analyzes
and straties the population to determine which members
meet criteria for one or more system-driven measures, and
those measures then become part of those patients’ care
plans. Whenever possible, system-driven objectives should
accrue to the benet of the patient. If there is a potential
conict between a system-driven objective (e.g., reducing
hospital readmission) and a patient’s needs, the patient’s
needs should overshadow the system-driven objective.
Person-Level Objectives
Person-level objectives are those elements of care or health
status improvement that may not be part of the value-based
contractual obligations of the provider, but are either neces-
sary or aspirational for the patient. Necessary person-level
objectives may be either correlated to system-driven objec-
tives or simply called for by standards, evidence, or best
128 Medical Practice Management | September/October 2015
www.greenbranch.com
| 800-933-3711
practices. Aspirational objectives often are health status,
functional, or outcomes-related goals for the patient that
may be unrelated to any quantiable criteria.
COLLABORATION AS KEYSTONE TO
POPULATION MANAGEMENT
Shared decision-making is increasingly considered a best
practice, and a measure of quality for value-based care.9
Consolidating the patient’s open issues into a single op-
erating framework via the Gordon Care Plan can simplify
and facilitate patient involvement in their action plan for
health and wellness, increasing the likelihood of high-level
patient engagement and involvement in the achievement
of care plan goals.10 is includes better understanding of
the conceptual foundation of goals being set by profession-
als, providing a personal context to the plan via person-
level goals, priorities, and preferences, and establishing a
mutual foundation for their relationship with, and perfor-
mance by, their health resource community.
Along with shared decision-making, the Gordon Care
Plan framework supports five critical success factors for
population health management (Table 2).
REMAPPING QUALITY MEASURES
AS CARE PLAN GOALS
Table 3 illustrates a practical application of the Gordon
care plan framework, showing a mapping of the 33 current
Accountable Care Organization (ACO) quality measures
for the Medicare Shared Savings Program11 (administered
by the Centers for Medicare & Medicaid Service) against
the Gordon care plan framework (excluding person-level
objectives).
Table 1. A Gordon Classication-Based Care Plan Framework
Clinical
Strategy
Wellness Universal
prevention
Selected
prevention
Indicated
prevention
Condition
management
Compassionate
care
Strategic
Target
Individual focus Community-
based
Characteristic-
based
Condition or risk-
based
Diagnosis or
event-based
Prognosis-based
Strategic
Framework
Targets whole
population to
achieve or sustain
levels of physical,
mental and social
well-being
Targets whole
population
(nation, local
community) and
aims to prevent
or delay universal
health risks or
conditions
Targets groups
or individuals
whose risk is
above average;
subgroups may
be distinguished
by traits such
as age, gender,
family history,
geography
Targets groups
or individuals
with an existing
condition or other
data or identiers
indicating
condition-related
risks
Targets groups
or individuals
with conrmed
diagnosis or
other condition
that is unstable,
whose quality of
condition-related
care does not
meet evidence-
based standards
or whose health
status is poor
Patients with any
serious illness who
have physical,
functional,
psychological, or
spiritual distress
as a result of their
conditions and/
or associated
treatments
Examples
of Care
Plan Goal
or Action
Improve
nutritional
decision-making
Flu vaccine;
seat belt usage;
weight screening;
dental hygiene
Mammograms
in women over
50; apnea screen
when BMI>30 +
snoring
Reduce CV risk
in DM (add
ACE inhibitor/
ARB); reduce
osteoporosis risk
with COPD Rx;
readmission risk
reduction; cancer
survivorship
Blood sugar
management in
DM; medication
management in
CHF; surgery for
appendicitis
Palliative care
hospice
ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; BMI, body mass index; CHF, congestive heart failure; COPD, chronic
obstructive pulmonary disease; CV, cardiovascular; DM, diabetes mellitus; Rx, prescription.
Table 2. The Gordon Care Plan Framework Supports Critical
Success Factors for Population Health Management
Clinical
integration
Serves as a central repository and universal
categorization scheme across all specialties
and disciplines and information systems
Knowledge
sharing
Goals inherently contain information about
patient’s condition and health status, serving
as a curated, goal-oriented view of the
patient’s entire data set
Real-time
exibility
As new data elements become available,
goals may be resolved, or new conditions may
be identied, requiring additions to the plan
Collaboration Represents a set of common goals across
the patient’s health resource community and
supports collective determination—shared
responsibility, authority, and accountability—
for achieving results
Resource-
managed care
delivery
Creates new opportunities to envision
alternative paths to goal achievement through
communications tools, community xtures, or
nonclinical personnel and drive innovation via
its application as a universal metadata solution
for care management resources
www.greenbranch.com
| 800-933-3711
Merahn | Knowledge Representation and Care Planning 129
Operationally, centralized care planning is a functional
requirement in the population health operating model,
so using the Gordon care plan framework is a matter of
configuration with minimal disruption. Current models
of evidence-based practice and order set development
provide the content basis of categorizing clinical goals and
determining the “standing orders” for the population under
management.12 Although there may be potential categoriza-
tion conflicts, the framework itself provides the rules for
resolution: weight management may be an independent
wellness goal for one patient, but the presence of related
conditions may make it a trigger for indicated prevention
in another. Although the Gordon Care Plan can be imple-
mented manually, the use of information technologies to
create and manage one is easily accomplished by congura-
tion of current electronic health record systems, analytics,
clinical decision support, and care management platforms.
CONCLUSION
Foreseeing Bowen’s 21st-century eorts to align learning
design with desired capacity for problem representation,
Bruner’s seminal 1960 work e Process of Education dis-
cussed the importance of structure as part of a learning
process he referred to as the “transfer of principle,” which
permits the “recognition of subsequent problems as special
cases of an idea originally mastered.”13
“The teaching and learning of structure, rather than
simply the mastery of facts and techniques, is at the cen-
ter of the classic problem of transfer . . . If earlier learning
is to render later learning easier, it must do so by pro-
viding a general picture in terms of which the relations
between things encountered earlier and later are made
as clear as possible.”13
As Bowen and subsequent authors have pointed
out, the structure of knowledge is essential for problem
Table 3. 2015 Centers for Medicare and Medicaid Services Medicare Shared Savings ACO Measures
Mapped Against Gordon Care Plan Framework
Wellness/
Lifestyle
Management
Universal
Prevention
Selected
Prevention
Indicated
Prevention
Condition
Management
Compassionate
Care
Individual Focus Community-
Based
Characteristic-
Based
Condition or
Result-Based
Diagnosis or
Event-Based
Prognosis-Based
EXAMPLE: 2014 ACO Medicare Shared Savings Program Quality Measures
System-Driven
Objectives:
Clinical*
Health
Promotion/
Education (5)
Health Status/
Functional Status
(7)
Flu Vaccination
(14)
Adult Weight
Screening (16)
Adult Tobacco
Use Assessment
(17)
Adult Depression
Screening (18)
Adult Blood
Pressure
Screening (21)
Falls Risk
Screening (13)
Pneumococcal
Vaccine (15)
Colorectal Cancer
Screening (19)
Mammography
Screening (20)
Documentation
of current
medications in
medical record
(39)
All Condition
Readmissions (8)
COPD/Asthma
Admissions (9)
CHF Admissions
(10)
CAD+DM/CHF:
% of patients
on ACE or ARB
therapy (33)
Skilled nursing
facility 30-day
all-cause readmis-
sions (35)
All-cause
unplanned
admissions for
patients with:
• diabetes (36)
• heart failure (37)
• multiple chronic
conditions (38)
DM: Eye exam
(41)
DM: HgbA1c<8%
(22)
DM: % of
patients
HgA1c>9% (27)
HTN: % of
patients
BP>140/90 (28)
IVD: % of
patients on
ASA or other
antithrombotic
(30)
LVSD: % of
patients on beta-
blocker therapy
(31)
CAD: % of
patients on Rx
to lower LDL
cholesterol (32)
Depression
Remission at 12
months (40)
Data from Centers for Medicare & Medicaid Services Quality Measure Benchmarks for the 2015 Reporting Year (Release Notes/Summary
Changes February 2015); (X) = CMS ACO Measure Number.
*Excludes patient experience measures 1, 2, 3, 4, 34.
ACE, angiotensin-converting enzyme; ACO, Accountable Care Organization; ARB, angiotensin receptor blocker; ASA, acetylsalicylic acid (aspirin);
BP, blood pressure; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; DM, diabetes
mellitus; HgbA1c, glycated hemoglobin; HTN, hypertension; IVD, ischemic vascular disease; LDL, low-density lipoprotein; LVSD, left ventricular
systolic dysfunction; Rx, prescription.
130 Medical Practice Management | September/October 2015
www.greenbranch.com
| 800-933-3711
representation and its subsequent application to clini-
cal reasoning and problem solving.14 Eorts to rene the
structure of medical knowledge will be critically important
as the healthcare community seeks to imagine and design
new models of care delivery that may break from tradi-
tional discipline-driven models.
Although clinical analytics can provide risk stratifica-
tion, predictive modeling, utilization management, and
identification of evidence-based gaps in care across the
population, the true keystone of successful population
management is the essential triad of care planning, care de-
livery, and collaboration, because that is where patients are
engaged in productive change toward health and wellness.
e structure of the Gordon Care Plan provides an opera-
tional framework for collaborative, resource-managed care
design by the people, platforms, programs, and services that
make up the patient’s health resource community.
Y
REFERENCES
1. Bowen JL. Educational strategies to promote clinical diagnostic rea-
soning. N Engl J Med. 2006;355:2217-2225.
2. Chang RW, Bordage G, Connell KJ. e importance of early problem
representation during case presentations. Acad Med. 1988;73(Suppl):
S109-S111.
3. Porter ME. What is value in health care? N Engl J Med. 2010;363:
2477-2481.
4. Mostashari F, Sanghavi D, McClellan M. Health reform and physician-
led accountable care: the paradox of primary care physician leader-
ship. JAMA. 2014;311:1855-1856.
5. Schoen C, Osborn, R, Squires D, etal. New 2011 survey of patients
with complex care needs in eleven countries nds that care is often
poorly coordinated. Health A (Millwood). 2011;30:2437-2448.
6. Jackson GL, Powers BJ, Chatterjee R, etal. e patient-centered medi-
cal home: a systematic review. Ann Intern Med. 2013;158:169-178.
7. Gordon R. An operational classication of disease prevention. Public
Health Rep. 1983;98):107–109.
8. Mrazek PJ, Haggerty RJ. Reducing Risks for Mental Disorders: Frontiers
for Preventive Intervention Research. Washington, DC: National Acad-
emy Press; 1994
9. Barry MJ, Edgman-Levitan S. Shared decision making—the pinnacle
of patient-centered care. N Engl J Med. 2012;366:780-781.
10. Hibbard JH, Greene J. What the evidence shows about patient activa-
tion: better health outcomes and care experiences; fewer data on
costs. Health A (Millwood). 2013;32:207-214.
11. Medicare Shared Savings Program Quality Measure Benchmarks for
the 2014 and 2015 Reporting Years. Washington, DC: Centers for Medi-
care & Medicaid Services. 2013; www.cms.gov/Medicare/Medicare-
Fee-for-Service-Payment/sharedsavingsprogram/Downloads/MSSP-
QM-Benchmarks.pdf . Accessed June 18, 2014.
12. Ballard DJ, Ogola G, Fleming NS, etal. e impact of standardized
order sets on quality and nancial outcomes. In: Henriksen K, Battles
JB, Keyes MA, etal., editors. Advances in Patient Safety: New Direc-
tions and Alternative Approaches. (Vol. 2: Culture and Redesign).
Rockville, MD: Agency for Healthcare Research and Quality; 2008.
13. Bruner J. e Process of Education. Cambridge, MA: Harvard Univer-
sity Press, 1960.
14. Mutnick A, Barone M. Assessing and remediating clinical reasoning.
In: Kalet A, Chou CL, eds. Remediation in Medical Education. New
York: Springer; 2014; 85-101.
ResearchGate has not been able to resolve any citations for this publication.
Article
Full-text available
Patient engagement is an increasingly important component of strategies to reform health care. In this article we review the available evidence of the contribution that patient activation-the skills and confidence that equip patients to become actively engaged in their health care-makes to health outcomes, costs, and patient experience. There is a growing body of evidence showing that patients who are more activated have better health outcomes and care experiences, but there is limited evidence to date about the impact on costs. Emerging evidence indicates that interventions that tailor support to the individual's level of activation, and that build skills and confidence, are effective in increasing patient activation. Furthermore, patients who start at the lowest activation levels tend to increase the most. We conclude that policies and interventions aimed at strengthening patients' role in managing their health care can contribute to improved outcomes and that patient activation can-and should-be measured as an intermediate outcome of care that is linked to improved outcomes.
Article
Full-text available
Around the world, adults with serious illnesses or chronic conditions account for a disproportionate share of national health care spending. We surveyed patients with complex care needs in eleven countries (Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, Switzerland, the United Kingdom, and the United States) and found that in all of them, care is often poorly coordinated. However, adults seen at primary practices with attributes of a patient-centered medical home--where clinicians are accessible, know patients' medical history, and help coordinate care--gave higher ratings to the care they received and were less likely to experience coordination gaps or report medical errors. Throughout the survey, patients in Switzerland and the United Kingdom reported significantly more positive experiences than did patients in the other countries surveyed. Reported improvements in the United Kingdom tracked with recent reforms there in health care delivery. Patients in the United States reported difficulty paying medical bills and forgoing care because of costs. Our study indicates a need for improvement in all countries through redesigning primary care, developing care teams accountable across sites of care, and managing transitions and medications well. The United States in particular has opportunities to learn from diverse payment innovations and care redesign efforts under way in the other study countries.
Chapter
Full-text available
Objective: The objective of this project was to valuate impact of a standardized order set on quality and financial performance. Methods: We conducted an observational study to examine order set use by hospital, discharge month, severity of illness and risk of mortality for pneumonia patients between March 2006 and September 2007. We also assessed impact on in-hospital mortality and 30-day readmission rates using four measures: (1) Cox proportional hazards regression, (2) Joint Commission Core Measures compliance using logistic regression, (3) length of stay, and (4) financial indicators using robust regression methods for highly skewed data. Results: A total of 3,301 patients met the inclusion criteria. Over 19 months, order set use increased by 55 percent. Order set use significantly improved in-hospital mortality [hazard ratio (95 percent confidence interval (CI): 0.66 (0.45; 0.97) or 0.67 (0.46; 0.98); and Core Measures compliance (relative risk, 95 percent CI: 1.24 (1.04; 1.48) or 1.22 (1.02; 1.45)] following covariate or propensity score risk adjustment. Conclusion: Evidence-based pneumonia order sets can reduce inpatient mortality and increase delivery of important care processes.
Chapter
Trainees must have excellent clinical reasoning skills to practice medicine safely and effectively. Even when a trainee has an impressive knowledge base, he or she can have difficulty applying that knowledge to patient problems. In this chapter, the authors discuss how the cognitive processes involved in decision-making apply in medicine. They propose a framework for how educators can teach and model decision-making to medical trainees based on the literature and their extensive experience with novice clinicians. They propose that learners should manifest progress of clinical reasoning in four ways: (1) an improved ability to develop and share a concise verbal or written problem representation; (2) an increasing and consistent use of semantic qualifiers; (3) the ability to state, seek, identify, and recall the defining and discriminating features of a patient’s history and physical exam and link this to their knowledge base of “illness scripts” and (4) demonstrate an increasing metacognitive awareness which reduces cognitive biases in patient evaluations. They provide detailed descriptions of an array of strategies to address immature clinical reasoning.
Article
The patient-centered medical home (PCMH) describes mechanisms for organizing primary care to provide high-quality care across the full range of individuals' health care needs. It is being widely implemented by provider organizations and third-party payers. To describe approaches for PCMH implementation and summarize evidence for effects on patient and staff experiences, process of care, and clinical and economic outcomes. PubMed (through 6 December 2011), Cumulative Index to Nursing & Allied Health Literature, and the Cochrane Database of Systematic Reviews (through 29 June 2012). English-language trials and longitudinal observational studies that met criteria for the PCMH, as defined by the Agency for Healthcare Research and Quality, and included populations with multiple conditions. Information on study design, populations, interventions, comparators, financial models, implementation methods, outcomes, and risk of bias were abstracted by 1 investigator and verified by another. In 19 comparative studies, PCMH interventions had a small positive effect on patient experiences and small to moderate positive effects on the delivery of preventive care services (moderate strength of evidence). Staff experiences were also improved by a small to moderate degree (low strength of evidence). Evidence suggested a reduction in emergency department visits (risk ratio [RR], 0.81 [95% CI, 0.67 to 0.98]) but not in hospital admissions (RR, 0.96 [CI, 0.84 to 1.10]) in older adults (low strength of evidence). There was no evidence for overall cost savings. Systematic review is challenging because of a lack of consistent definitions and nomenclature for PCMH. The PCMH holds promise for improving the experiences of patients and staff and potentially for improving care processes, but current evidence is insufficient to determine effects on clinical and most economic outcomes.
Article
One example is the Palm Beach ACO, which is self-funded by physicians in independent practices and has a service base of 30 000 Medicare beneficiaries. The physicians who established this ACO in 2012 have focused on understanding and addressing the key drivers of avoidable costs for their patient population. They have implemented systematic improvements in the care transitions for their patients, seeking notifications about emergency department visits, admissions, and discharges, in some cases directly to the smartphone of the physician. They have worked with nursing homes and home health agencies to set new expectations for improved communications and coordination, invested in increased patient outreach to ensure increased uptake of wellness and care transition encounters, and provided regular feedback of use patterns to physicians (K. Conroy and H. Zucker, Palm Beach Accountable Care Organization, written communication, January 31, 2014). When the early result of the first cohort of 114 Medicare Shared Savings Program ACOs were recently released, the Palm Beach ACO was 1 of 29 that exceeded the savings threshold; the ACO saved 22millioninprojectedcostsinthefirstyear,receivingnearly22 million in projected costs in the first year, receiving nearly 11 million, or approximately $63 000 per member physician.⁶
Article
The most important attribute of patient-centered care is the active engagement of patients when fateful health care decisions must be made — when they arrive at a crossroads of medical options, where diverging paths have different and important consequences.