A total of 8 samples were collected from strategic points along the Ugborikoko/Okere creek. The levels of the physico-chemical parameters and heavy metal pollutants were determined. Results of both physico-chemical characteristics and heavy metals revealed some degree of pollution in the creek. The mean values of pH, temperature, turbidity, conductivity, total dissolved solids, total suspended solids and chloride were 6.8, 30.3°C, 106.53 NTU, 471.45 ohms/cm, 354.56 mg/l, 123.56 mg/l and 78.11 mg/l respectively. The average value obtained for oil and grease was 14.13 ppm. The average value for the heavy metals were 2.258 ppm for iron, 0.0729 ppm for cadmium, 0.4225 ppm for zinc, 0.0997 ppm for manganese, 0.0236 ppm for copper, 0.2117 ppm for nickel. The results obtained indicated a significant level of pollution of the Ugborikoko/Okere creek. It was observed that the levels of iron, lead, chromium, cadmium, manganese and nickel in the samples were not in compliance with recommended standards set by world health organization for inland (fresh) and potable water.