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Conditions of the Reproductive Organs

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... An increase in the number of inflammatory cells and the production of inflammatory cytokines can cause pelvic inflammation owing to local and systemic responses of the immune system (55,56). Growth factors and inflammatory mediators secreted by peritoneal leukocytes are involved in the pathogenesis of the disease through an increase in the number of endometrial cells at ectopic sites, whereas many inflammatory cells and mediators, such as proteolytic enzymes, peritoneal macrophages, complement fragments, prostaglandins (PG), IL-1, and TNF, are produced in the peritoneal fluid of patients suffering from the disease (57). ...
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The objective was to review the different diagnostic methods and medical treatments for endometriosis. It was reviewed the Latin-American and international bibliography using the Pub-Med, Google Scholar, Springer, the Cochrane Library, Embase, Scielo, Imbiomed-L, Redalyc, and Latindex websites. The searches included the keywords: endometriosis, endometriotic, endometrial and ectopic endometrium, angiogenesis, angiogenesis and endometriosis, endometriosis, and medical treatment, endometriosis, and new treatment.
... Medication of the sexual partner (with antibiotics) was also considered necessary for the success of the study. Bromelain is a significant proteolytic component in the management of cervical dysplasia (Kaye et al. 2012;Romm et al. 2010b). ...
Chapter
Enzymes are the chemical compounds which act as a biological catalyst and alter the rate of biochemical reactions. There are about 3000 enzymes in our bodies which are involved in more than 7000 metabolic reactions. Considering the physiological and metabolic significance of the enzymes, food enzymes constitute an important part of diet. There are some enzyme-rich foods that are believed to have a different function in the human body than that of body’s own enzymes. But, processing and cooking of foods completely degrade the enzyme contents and leave the body deprived of these important enzymes which play a significant role in the well-being and healthcare. Some prominent examples of high enzyme foods are papaya, pineapple, banana, figs, and bee pollen. The sprouts are metabolically very active, and the content of enzymes is more as compared to seeds. The dietary enzymes commonly present in the enzyme-rich foods are proteinases, amylases, maltases, lipases, papain, bromelain, etc. Non-processed and uncooked foods are rich in enzymes, and their intake might decrease the body’s burden to produce more and more of its own enzymes. As a result of some metabolic disorders and diseases, the production of some specific enzymes is hampered in the body. In such cases, foods which are high in enzyme contents are the best choice for the extraction, purification, and commercialization of the enzymes. These enzymes find numerous applications in pharmaceutical industries, and there is a need for exploiting these foods for industrial applications.
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Endometriosis is a disease in which the lining of the endometrium is found outside of the uterus. Recent medical treatments for endometriosis have adverse effects, limiting their long-term use. Furthermore, the recurrence of the disease after the cessation of therapy is quite common, and most patients need to continue treatment to maintain a hypoestrogenic environment till conception. Notwithstanding recent advances in computational and chemical practices, traditional medicines are considered the most consistent sources for the discovery of new drugs. Numerous medicinal plants and plant-derived compounds have been tested against gynecological disorders, mainly endometriosis. This review aimed to describe the pharmacological activity profile of the medicinal plants and their active ingredients and draw attention to the discovery of multitargeted drug molecules for rational therapy.
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The fiuctuations in the total phenolic content and antioxidant activity of the ethanolic extract of Viburnum opulus fruits were studied. The total phenolic content was determined using the Folin-Ciocalteu assay. To determine the antioxidant activity, the 2,2'-azinobis-3-ethyl-benzthiazino-6-sulphonic acid (ABTS) test was applied. Results indicate that no correlation can be made between the total phenol content and the antioxidant capacity of the extract during refrigerated storage.
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