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Abstract

The process of knowledge production exhibits a very distinctive geography. This article argues that this geography is fundamental, not incidental, to the innovation process itself: that one simply cannot understand innovation properly if one does not appreciate the central role of spatial proximity and concentration in this process. The goal of this article is to demonstrate why this is true, and to examine how innovation systems at the subnational scale play a key part in producing and reproducing this uneven geography over time. This article addresses four key issues. First, it looks at the reason why location matters when it comes to innovative activity. Second, it turns to examine regional innovation systems, and the role played by them in generating and circulating new knowledge leading to innovation. Third, the article considers the relationship between regional systems of innovation and institutional frameworks at the national level. Finally, the relationship between local and global knowledge flows is examined.
... Hence, it can be expected that firms dependent on new scientific findings will be located near the respective places. One essential mechanism behind the clustering is the exchange of tacit knowledge: While codified knowledge is easily accessible, tacit knowledge is created, disposed and disseminated through personal interaction (see Asheim and Gertler 2006;Heimeriks and Boschma 2014;Maskell and Malmberg 1999;Wal 2014). This was investigated in particular for the biotechnology industry by Cortright and Mayer (2002), wherein biotechnology clusters emerged in geographical proximity to pharmaceutical manufacturers, and also Messeni Petruzzelli et al. (2015) who affirm the innovative relationship between those two industries. ...
... Such a dependence on former related activity can also be found with respect to scientific activity, although with a lower importance. When distinguishing between industries with a synthetic knowledge base versus an analytical one (Asheim and Coenen 2005), the bioeconomy, at least biotechnology, has a rather analytical knowledge base (Asheim and Gertler 2006). Whereas industries with a synthetic knowledge base receive innovative ideas predominantly from interaction with customers or other users than from scientific research, industries with an analytical knowledge base usually rely on close links to universities and research institutions, i.e., they have many joint research projects. ...
... Thus, we can expect spatial proximity to be of great importance for circulating knowledge within the bioeconomy. Knowledge spillovers will happen firstly, fast, and most accurately within the local (and social) networks of the actors involved (Asheim and Gertler 2006). This happens even before findings are published and hence become codified analytical knowledge. ...
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The literature provides clear evidence that the kind, amount, and location of innovation activity changes during the life cycle of industries. However, the relevant literature in this respect focuses on large, long-existing industries such as the automobile industry, while it is unclear whether smaller technological fields show similar influences of life cycle processes on the location of innovation activity. Hence, we analyze the life cycle stages of various fields in the bioeconomy and the location of the respective innovation activity in Germany. Within the three fields of biomass, biotechnology, and biomaterials, subfields were built through a keyword-driven approach. We conduct a logit regression model to check the influence of population density, prior topic-specific patents and publications, as well as the overall patent and publication activity on the emergence of bioeconomy patents. The results indicate that the researched bioeconomy mainly follows the stylized life cycle concepts. Moreover, they show that most of the studied subfields do not integrate into existing technologies but build their own innovation systems and that bioeconomy patents rather emerge in rural areas. Interestingly, we find a deviation from the standard life cycle stages, which seems to be caused by the crossover-technology characteristics. We call it the dandelion rubber effect: After the usual initial phase, there seems to be a phase in which the possibilities of application are extended, widening the field instead of becoming more specialized and leading to a new science-based innovation activity. Furthermore, path dependence is clearly visible in bioeconomy patent locations.
... With regard to the procedural dimension, our findings confirm the established understanding that all types of proximity are relevant for the (co-)creation of innovations (in our case bioeconomy innovations), albeit to varying degrees, thereby also seconding seminal research on RIS and the stickiness of tacit knowledge (Asheim & Gertler, 2006;Asheim & Isaksen, 2002). While less relevant in the context of a biotechnology-centered vision, geographical proximity to resource providers is deemed an important success factor for developing biomass-based innovations, especially when linked to the ideas of circular economy and cascading resource use (see also Bourdin & Torre, 2025, for the relevance of proximity in the circular economy). ...
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This article explores the regional embeddedness of bioeconomy innovations in Germany, focusing on “flagship” innovation projects that exemplify the challenges and opportunities of systemic changes towards bioeconomies. While bioeconomies have been promoted as solutions to global challenges and opportunities for sustainable regional development, there are ongoing debates about the actual benefits of bioeconomies. These debates result not least from diverging visions of both bioeconomy and innovation. The concept of regional embeddedness shows promise for addressing such issues but needs empirical refinement and conceptual substantiation. Therefore, our study investigates how innovators perceive their bioeconomy innovations to be regionally embedded and which regional challenges and opportunities they identify, using a qualitative multiple-case study approach. More precisely, we report the findings from 16 interviews with experts involved in “flagship” innovations in the German bioeconomy. Our findings highlight the heterogeneity of bioeconomy visions and corresponding innovations and confirm the relevance of different types of proximity. Moreover, higher education institutions and research institutes are found to play a key role in driving bioeconomy innovations, which may, however, contribute to regional differences in capacities and capabilities for sustainable bioeconomy innovations and transitions. Building on our findings, we propose a first conceptual framework incorporating both procedural and effectual dimensions of regional embeddedness. Generally, our article provides insights for policymakers, innovators, and other scholars interested in better understanding and governing bioeconomies through regionally embedded innovation processes.
... O uso da metáfora ecológica de um ecossistema, nos estudos de gestão (Moore, 1993;Iansiti & Levien, 2004), foi enriquecido com o conceito de ecossistema de inovação (Adner, 2006). O conceito do ecossistema de inovação foi introduzido como um conjunto dinâmico e colaborativo de atores, relacionamentos e instituições, afetando o processo de inovação sustentável dentro de uma região (Asheim & Gertler, 2005;Romano et al., 2014). No ecossistema existe um conjunto de um grande número de participantes, interligados entre si, composto de clientes, fornecedores, concorrentes, distribuidores, terceirizados diversos, fornecedores de tecnologia e instituições ligadas através de muitos tipos de relacionamentos. ...
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The version of record [Bathelt, H. (2003). Geographies of production: Growth regimes in spatial perspective 1 – Innovation, institutions and social systems. Progress in Human Geography, 27(6), 763-778.] is available online at:http://phg.sagepub.com/content/27/6/763 [doi: 10.1191/0309132503ph462pr]
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