Large-scale shaking table test was performed to study dynamic response characters and failure mechanism of rock slopes triggered by Wenchuan earthquake. Sine waves with different frequencies, amplitudes and duration times were mainly input. Testing results show that: acceleration amplification coefficients increased nonlinearly with the increasing elevation, and they almost reach to maximum at slope surface and shoulder. Horizontal acceleration is amplified more obvious than vertical acceleration at top part of slope (above three-quarters of slope height) which is the opposite at the lower part. Acceleration amplification coefficients increased with the increasing seismic frequency nonlinearly; distribution of acceleration in slope body changed with variation of frequency. Once the input frequency approximated to the natural frequency of model slope, dynamic acceleration is amplified most obviously. Acceleration amplification coefficients increased with the increment of seismic wave amplitude; but amplitude doesn't change the distribution of acceleration in slope body. Duration time of seismic wave has little influence on dynamic characters. Slope structure controls the deformation modes of rock slope; and acceleration amplification coefficients of bedding slope are about 15% more than those of the homogeneous slope, because of a large amount of structural surfaces in bedding slope which can make propagation of seismic wave more complex.