... These molecules that possess a strong CNS affinity may also be involved in the placebo response (besides dopamine and serotonin) (Fuente-Fernandez, Schulzer, & Stoessl, 2002;Sher, 2003) and facilitate positive CAM effects or subjective feelings of wellbeing and relaxation. Moreover, they own a stress-antagonizing capacity -like CAM Stefano, et al., 2003;Benson, 1984;de la Torre & Stefano, 2000;Esch, 2003c;Esch, 2003b;Salamon, et al., 2003;Spintge, 1985;Steelman, 1990;Knight & Rickard PhD, 2001;Fricchione, Mendoza, & Stefano, 1994;Moyer, Rounds, & Hannum, 2004;Diego, Field, Sanders, & Hernandez-Reif, 2004;Walach, Guthlin, & Konig, 2003;Lund, et al., 2002;Piotrowski et al., 2003;Woods & Dimond, 2002;Wikstrom, Gunnarsson, & Nordin, 2003;Yun, et al., 2002;Lim, Ryu, Kim, Hong, & Park, 2003). The relief of stress or detrimental effects related to stress, i.e., stress-associated diseases, may be due to the CAM-connected reduction of norepinephrine reactivity/turnover or a decreased autonomic nervous system hyperresponsiveness (e.g., see Esch, 2003b;Woods, et al., 2002;Yun, et al., 2002)). ...