Interactive factors of stress were examined by comparing a group of elderly family caregivers to a control goup of noncaregiving peers. The groups were compared on their perceptions of positive and negative aspects of daily activities as well as on the relationship between these perceptions and psychological symptoms. A daily experience list, the RUCHL (Routines, Uplifts, Challenges, and Hassles ... [Show full abstract] List), and the HSCL (Hopkins Symptom Checklist) were administered to each respondent. A buffering effect of positive experiences did not emerge; positive scores did not interact with negative scores, nor did they interact with group membership in predicting overall psychological symptoms. Caregivers rated greater negative impact in everyday experiences than did noncaregivers, whether or not experiences directly related to caregiving were included. The ratings of positive impact were higher than for negative impact and were similar in both groups. Negative impact scores predicted psychological symptoms for both groups, whereas positive impact scores did not.