Prevalence of Oral Mucosal Lesions in Patients Attending Oral Diagnosis Clinic at School Of Dentistry, University Of Sulaimani

Abstract

Objective: To report prevalence of oral mucosal lesions in patients attending oral diagnosis clinic at school of dentistry for seeking dental treatment. Patients and Methods: A cross-sectional study was carried out among patients (n=1325) who were visiting the Department of Oral Diagnosis at School of Dentistry, University of Sulaimani; of which; 650 (49.05%) were male and 675 (50.94%) were female aged from 10-79 years with mean age= 44.5±12.64 years, demographic information (age, sex) were obtained as well as clinical examination including features of the lesion, anatomical location, extension were also collected from patients. The lesions that could not be diagnosed by clinical examinations alone were analyzed histopathologically. Chi square test was used to analyze the data. Result: Prevalence of oral lesion was 2.64%. The most common detected oral lesion was recurrent aphthous ulceration (0.75%). Oral mucosal lesions were more prevalent among females (2.81%) than males (2.46%); however it was not statistically significant (P=0.68). The vast majority of oral lesions were seen in age group of 20-39 years (60.52%) where as the most common location for oral lesions were buccal mucosa (25.71%) Conclusion: Routine examinations of oral cavities is important in diagnosing several oral lesions and this will help practitioners to establish early diagnosis and treatment and better prognosis

Full text

IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 14, Issue 6 Ver. VIII (Jun. 2015), PP 62-66
www.iosrjournals.org
DOI: 10.9790/0853-14686266 www.iosrjournals.org 62 | Page
Prevalence of Oral Mucosal Lesions in Patients Attending Oral
Diagnosis Clinic at School Of Dentistry, University Of Sulaimani
Dr. Faiq Mohammad Amen1, Dr. Shokhan Ahmad Hussein2,
Dr. Mustafa Jamel Abdullah3
B.D.S., M.Sc.Oral Medicine, Oral Medicine Clinic of the school of dentistry, University of Sulaimani,
Kurdistan region, Iraq
Abstract:
Objective: To report prevalence of oral mucosal lesions in patients attending oral diagnosis clinic at school of
dentistry for seeking dental treatment.
Patients and Methods: A cross-sectional study was carried out among patients (n=1325) who were visiting
the Department of Oral Diagnosis at School of Dentistry, University of Sulaimani; of which; 650 (49.05%) were
male and 675 (50.94%) were female aged from 10-79 years with mean age= 44.5±12.64 years, demographic
information (age, sex) were obtained as well as clinical examination including features of the lesion,
anatomical location, extension were also collected from patients. The lesions that could not be diagnosed by
clinical examinations alone were analyzed histopathologically. Chi square test was used to analyze the data.
Result: Prevalence of oral lesion was 2.64%. The most common detected oral lesion was recurrent aphthous
ulceration (0.75%). Oral mucosal lesions were more prevalent among females (2.81%) than males (2.46%);
however it was not statistically significant (P=0.68). The vast majority of oral lesions were seen in age group of
20-39 years (60.52%) where as the most common location for oral lesions were buccal mucosa (25.71%)
Conclusion: Routine examinations of oral cavities is important in diagnosing several oral lesions and this
will help practitioners to establish early diagnosis and treatment and better prognosis
Keywords: prevalence, oral lesion, oral diagnosis, Sulaimani.
I. Introduction
Oral health is important to the quality of life of all individuals. Oral lesions can cause discomfort or
pain that interferes with mastication, swallowing, and speech. Oral lesions can produce symptoms such as
halitosis, xerostomia, or oral dysesthesia, which interfere with daily social activities (1). Further more, poor oral
hygiene, sharp teeth, and improperly fitting dentures have been thought to play a role in the occurrence of oral
mucosal lesions (2,3). Denture wearers, besides suffering the characteristic lesions from their ill fitted dentures,
they present traumatic ulcerations more frequency than nonusers, candidosis may occupy second place in
frequency (4,5,6). Oral disease is a health problem that is not only a matter of oral hygiene and local condition,
but can also be a precursor to other dangerous and potentially life threatening illnesses (7). According to
different investigations, it is a common finding to observe oral pluripathology in the elderly. This could be
explained due to high frequency of systemic diseases, aging process, metabolic changes, nutritional factors,
medications, prosthetic use, psychobiological habits and alcohol or tobacco use; therefore, several conditions
should be encounter in this particular age group (8,9) Diagnosis of wide variety of lesions that occur in the oral
cavity is an essential part of dental practice. An important element in establishing diagnosis is the knowledge of
the lesions relative frequency, or prevalence at one point of time (10). Oral health survey data are essential for
proper health planning programs. The pattern of disease may be affected by many factors including patients
awareness, changes in lifestyle and increasing interest in oral health. (11). In Sulaimani city there is a great need
for clinical studies to establish baseline data on the prevalence of oral lesions and there are few studies were
done regarding prevalence of oral lesions. The aim of this study is to detect prevalence of oral mucosal lesions
in patients attending oral diagnosis clinic at school of dentistry, university of sulaimani.
II. Patient And Methods
A cross-sectional survey was carried out among patients (n=1325) who were visiting the department of
Oral Diagnosis at school of dentistry, university of sulaimani along 7 successive months (September 2013-
April 2014) for seeking dental treatment. This research was approved by the Committee of Ethics at Research of
the University of Sulaimani. According to Declaration of Helsinki, signed consent forms were obtained from all
participants before conducting the study (12). 650 (49.05%) were male and 675 (50.94%) were female. The
patients were categorized into four age groups: less than twenty, twenty to thirty nine years (young age), forty to
fifty nine years, (middle age) and equal and more than sixty (old age). An interview was conducted to collect

Prevalence of oral mucosal lesions in patients attending oral diagnosis clinic at…
DOI: 10.9790/0853-14686266 www.iosrjournals.org 63 | Page
information using a structured questionnaire including patient demography (age and sex) during the clinical
examination, the following elements including features of the lesion, anatomical location, and extension were
analyzed as well as dental and general medical histories of the patients were obtained. At the time of clinical
examination, we established a preliminary diagnosis. Some of the mucosal changes were diagnosed solely by
clinical examination the diagnosis was made based on history, clinical features, and investigations according to
theWHO (1997) criteria (13). When clinical features were not diagnostic and where no clinical improvement
was observed, a biopsy was undertaken.
SPSS version 16 (Statistical Package for the Social Sciences) was used. The prevalence of oral lesions
was analyzed regarding the total number of the subjects, for females and males separately. Comparisons were
then carried out using Pearson chi-square test. P-values of less than 0.05 were regarded as statistically
significant and P-values of less than 0.01, and 0.001were regarded as highly significant, while P-values of more
than 0.05 were considered as insignificant.
III. Result
The present study comprised 1325 patients attending oral diagnosis clinic; of which; 650 (49.05%)
were male and 675 (50.94%) were female; aged from 10-79 years, prevalence of oral lesion in this study sample
was (2.64%); the most common reported oral lesion was recurrent aphthous ulceration (0.75%) followed by
traumatic ulcer (0.37%), and denture stomatitis (0.30%) and Recurrent aphthous ulceration was more prevalent
among males (1.07%) than females (0.44%); however; it was not statistically significant (P=0.18). Total oral
mucosal lesions were more prevalent among females (2.81%) than males (2.46%); however it was not
statistically significant (P=0.68) (Table1).
The total oral lesions showed greater significant distribution in age group 20-39 years, (60.52%)
(P=0.02), followed by 40-59 years (18.42%) and ≥60 years (15.78%) were it showed statistically significant
prevalence of oral mucosal lesion than age group 40-59 years (P=0.01) and ≥60 years (P=0.02) While the
occurrence of oral lesions in age group below 20 years comprised the lowest proportion (5.26%). The highest
frequency of recurrent aphthous ulceration was seen in 20-39 years (90%), while denture induced hyperplasia
has reached the highest distribution among ≥60 years patients however it was not statistically significant
(P=0.50) (Table 2).
The most common site for oral mucosal lesions was the buccal mucosa (25.71%) the second affected
sites were palate (20%) and Lip and tongue each (17.14%); however it was not statistically significant (P=0.05),
while the least common involved site was the mucobuccal fold of maxilla and mandible (2.85%) as
demonstrated in Figure 1.
IV. Discussion
Oral mucosal conditions and diseases may be caused by infectious diseases (bacterial or viral),
systemic diseases (metabolic or immunologic), drug-related reactions, or lifestyle factors such as the
consumption of tobacco, betel quid, or alcohol (14). The prevalence of oral mucosal disease has been found to
be higher in older patients than in younger individuals (15). Furthermore a relation has been reported between
oral mucosal disorders and aging (15,16). However age is not the only factor that correlating with diseases of
the oral mucosa; other factors such as trauma, the effects of medications, and oral and denture hygiene also play
a role (15). Epidemiological studies performed over the past few years have shown considerable variation in the
prevalence of oral mucous lesions among different regions throughout the world (17). There are considerable
methodological problems related to the absence of standard protocols and the wide variation in the methods
used. Consequently, the prevalences found for each lesion vary widely among research groups (17).
In the current study the prevalence of total oral mucosal lesion was (2.64%), this result is comparable
with a study done by Saraswathi et al. (18). (4.1%). On the other hand other investigator reported high value in
different countries which were (57%, 41.2%, 15.5%) respectively (8, 19, 20). These variations could be related
to many factors, different methodologies used, sex and age distribution of the sample, Specific cultural habits
like smoking and use of alcohol, variation in the clinical interpretation of parameters, real geographical
distributrion differences of oral lesions, racial factor, educational level of the patients, socioeconomic factors,
cultural levels, medication used, systemic diseases, use of dentures, food type and sample size included in the
study. The most common reported oral mucosal lesion was recurrent aphthous ulceration followed by
traumatic ulcer and denture stomatitis.
In a study by Gaphor and Abdullah (6) fissured tongue was the most common reported lesion. In
another study done by Najm, (21) the most common reported lesion were ulcerated lesion including traumatic
ulcer, in an Italian study by Campisi et al. (3) different total percentage of oral lesion was found (81.3%), with
the most common types of lesion noted were coated tongue (51.4%), leukoplakia (13.8%), traumatic lesions

Prevalence of oral mucosal lesions in patients attending oral diagnosis clinic at…
DOI: 10.9790/0853-14686266 www.iosrjournals.org 64 | Page
(9.2%), and actinic cheilitis (4.6%). Mujica et al (8) reported denture stomatitis as the most common oral lesion
followed by oral leukoplakia, and hemangioma.
The highest prevalence of oral lesions was in 20-39 years which is in agreement with other study done
by Gaphor and Abdullah (22), Probably because majority of patients attending oral diagnosis clinic are of
young aged.
In this study oral mucosal lesions were more prevalent among females than males, similarly Al-
mobeeriek and Aldosari (11) found higher frequency of oral lesions among females. Probably females are more
sensitive and are more concern about their oral and general health than males as was shown in this study that a
higher number of female patients attending oral diagnosis clinic at School of Dentistry. On contrary Pentenero
et al. (23) reported higher prevalence of oral lesions among males than females.
The present study also showed that recurrent aphthous ulceration is more frequent in male than females
which was in agreement with the result of a study performed by Rivera-Hidalgo et al. (24) who found a higher
prevalence of RAU among males. On contrary, Abdullah (25) and Gaphor and Hussein (26) reported RAU to
be more common among females. Perhaps because sample size was different or using different criteria for data
collection. There is some evidence that the disease has a high distribution in younger adults, decreasing in both
incidence and severity with age (27). This study revealed the highest prevalence of recurrent aphthous
ulceration was in 20-39 years. The same result was seen by Abdullah (25) in sulaimani.
The most common location for oral lesions were buccal mucosa followed by palate; Similarly in a
study by Gaphor and Abdullah (6) and in another study done by Garcia pola et al (28) buccal mucosa was the
most common location for oral lesions
In conclusion oral health is important and affect quality of life of patients therefore dentist can have an
active role in detection and early diagnosis of several oral lesions and subsequently an accurate treatment which
result in reducing complications associated with delay in diagnosis and result in good prognosis.
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Table1. Prevalence of oral lesions according to sex
Table 2. Distribution of 35 patients reported oral lesions according to age
Oral lesions
Male
N=650
N (%)
Female
N=675
N (%)
Total
N=1325
N (%)
P-value
Recurrent aphthous ulceration
7 (1.07)
3 (0.44)
10 (0.75)
0.18
Traumatic ulcer
1 (0.15)
4 (0.59)
5 (0.37)
0.19
Denture stomatitis
00 (00.00)
4 (0.59)
4 (0.30)
0.04
Denture induced hyperplasia
2 (0.30)
2 (0.29)
4 (0.30)
0.97
Candidiasis
2 (0.30)
1 (0.14)
3 (0.22)
0.54
Recurrent herpes simplex
1 (0.15)
1 (0.14)
2 (0.15)
0.97
Geographic tongue
2 (0.30)
00 (00.00)
2 (0.15)
0.14
Lichen planus
00 (00.00)
1 (0.14)
1 (0.07)
0.32
Hemangioma
1 (0.15)
00 (00.00)
1 (0.07)
0.30
Fibroepethelial hyperplasia
00 (00.00)
1 (0.14)
1 (0.07)
0.30
Mucocele
00 (00.00)
1 (0.14)
1 (0.07)
0.32
Mucoepidermoid carcinoma
00 (00.00)
1 (0.14)
1 (0.07)
0.32
Total
16 (2.46)
19 (2.81)
35 (2.64)
0.68

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DOI: 10.9790/0853-14686266 www.iosrjournals.org 66 | Page
25.71
20
17.14
17.14
11.42
5.71
2.85
0
5
10
15
20
25
30
buccal mucosa
Palate
tongue
lip
lower ridge
upper ridge
Mucobuccal fold
Figure 1.prevalence of oral lesions according to location