Animals have dietary strategies that aid in the suppression or control of disease and wounds. In Kahuzi-Biega National Park, only a few plant species have been observed regularly to be consumed by apes and constitute their basic staple food. Some plants have active constituents that may play an important role in diseases treatment. Phytochemical screening was conducted on 9 plant species most common in the diets of Kahuzi apes. The presence of important bioactive chemical components, including saponins, terpenoids, steroids, alkaloids, flavonoids, phenols, quinons and glycosids, well known for their role in disease treatment, were isolated. Bromatological analyses of selected fruits most preferred by both apes were also conducted and some fruits were found to be rich in, important nutritional components such as lipids, proteins and carbohydrates. Intestinal parasites of these apes were also investigated. A total of 19 different parasite species were identified fresh apes fecal samples collected in their home range. The prevalence rates of Coccidies were 94 and 93.4 % in Gorilla and chimpanzees fecal samples, respectively in the most prevalent parasites in both sympatric ape species. Protozoa and Nematoda parasite groups were the most observed. This study suggests that fruits preferentially eaten by gorillas and chimpanzees inhabiting Kahuzi-Biega National park contain essential chemical constituents that may be effective in parasite disease control maintenance and nutrition purpose. © 2015, International Journal of Pharmacognosy and Phytochemical Research. All rights reserved.