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Magnesium Supplementation in allergic diseases (Rhinitis)
... The use of magnesium in immunology has been studied in allergic rhinitis and asthma it has been suggested that intracellular calcium concentration increase in response to IgE stimulation leading to histamine release. This can be antagonised by magnesium [11] . Action of magnesium sulphate in eclampsia: -The precise site of action of magnesium sulphate in eclampsia is not known. ...
... The use of magnesium in immunology has been studied in allergic rhinitis and asthma. [11] It protects hippocampel cell culture from anoxia, relieves cerebral vasospasm, magnesium sulphate has been shown to obtund the hypertensive response to intubation in patients with pre-eclampsia without causing neonatal depression . Conventional strategies for obtunding the hypertensive response to intubation, such as beta block, topical local anaesthesia, opioid and vasodilators appear to be less effective in pre eclampsia conventional strategies for obtunding the hypertensive response to intubation, such as beta block, topical local anaesthesia, opioid and vasodilators appear to be less effective in pre eclampsia. ...
... This can be antagonized by magnesium. 184 In asthma, bronchospasm (requiring increased intracellular calcium) is antagonized by magnesium. This is discussed below. ...
Magnesium has an established role in obstetrics and an evolving role in other clinical areas, in particular cardiology. Many
of the effects involving magnesium are still a matter of controversy. Over the next decade, it is likely that improvements
in the measurement of magnesium, a clearer understanding of the mechanisms of its actions and further results of clinical
studies will help to elucidate its role, both in terms of treating deficiency and as a pharmacological agent.
In Deutschland ist die Magnesium-Versorgung in der Regel unzureichend. Nur wenige Bürger nehmen täglich 400 mg mit der Nahrung auf. Physischer Stress, Erkrankungen wie Diabetes und zahlreiche Medikamente erhöhen den Bedarf. Zum Ausgleich können pharmazeutische Magnesium-Präparate eingenommen werden. Doch nur eine mehrwöchige Supplementierung erhöht die intrazelluläre Konzentration.
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