In the past two decades, cutting edge technologies such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), epidural motor cortex stimulation (MCS) and deep brain stimulation (DBS), have been shown to be effective tools for modulation of neural excitability. Since then, these techniques have been explored for the management of numerous medical conditions, ... [Show full abstract] including pain management. The rationale for the use of brain stimulation in the treatment of pain is based on recent findings that patients with various chronic pain syndromes present with pathological changes in brain excitability, and that modulation of such changes can be paralleled by pain relief. TMS, tDCS, MCS or DBS have been shown to be effective tools for modulation of neural excitability, and have been in the past two decades implemented into research and clinical practice of pain management in patients with various difficult-to-treat neuropathic pain syndromes. Findings from controlled trials indicate that brain stimulation techniques have significant clinical potential in the treatment of chronic pain in selected patient-populations. This chapter reviews and discusses the use of invasive- and non-invasive brain stimulation in the treatment of neuropathic facial pain. Presented information can serve as a useful resource for future brainstimulation studies and for implementation of novel non-pharmacological techniques into management of chronic facial pain.