The purpose of this investigation is to define, first, wisdom from the point of view of the cognitive approach, and, second, to integrate this definition with the aspects of wisdom as defined by the semantic, cognitive, psychological approaches as well as to a certain degree by the philosophical approach. The research is based on an interdisciplinary view of the main aspects of wisdom’s ... [Show full abstract] development and their interdependency. Among the findings are: wisdom is information reflecting good judgment and choice; it is the final cognition unit in the Semantic Ladder and has different levels of scope and quality depending on the four minds, namely basic, whole, global and universal mind, which are supported by the art of living, understood as the reflection of behavioral aspects of wisdom within the philosophical framework of the hierarchy of possible purposes of one’s life. Practical implications: Wisdom can be accomplished in all phases of living. Social implication: The quest for wisdom should be achieved by teaching wisdom once it is defined. Originality: This investigation, by providing an interdisciplinary and civilizational approach, allows for the teaching and application of wisdom in a typical manner as is done by other disciplines and their issues.