ArticlePDF Available

Development of the CALS-Technology of Drying-Agglomeration Process in Production of Biologically Active Additives of the New Generation

Authors:
  • R&D Centre "Fine Chemicals"

Abstract and Figures

In this work, using CALS (Continuous Acquisition and Life Cycle Support) methods, an information model was elaborated which includes all steps (marketing, design, production, service and repair, and realization and sale) of technology for producing biologically active additives of a new generation from an extract of medicinal herbs and gelatin-starch complex. At the design step, initial data for design are analyzed, which contain information on six basic stages: grinding of medicinal raw material, extraction, concentration, mixing, drying-agglomeration, and packing. Particular attention was given to limiting stage of sol-gel transfer – drying-agglomeration. Main methods for drying biologically active additives were analyzed: spray, fluidized-bed, infrared drying and drying in a vacuum dryer equipped with rake agitator. It was shown that equipment considered is inefficient if the product contains astringent substances, which, during drying-agglomeration, form clots and can render the apparatus inoperative. Therefore, a continuous convective agitator dryer was proposed, which gives a product of required quality. At the design step, four variants of agitator design are considered. The ultimately chosen variant was the design that ensured required product quality at minimal energy consumption, with agitator being constructed at minimal expenditures. Three methods for introducing heat-transfer medium were analyzed, and optimal variant ensuring maximal uniformity and efficiency of heat transfer was chosen. Intermediate and final variants described in text and graphic files were included into CALS project. Developed CALS documentation significantly reduces service, maintenance, and repair costs. Therefore, one can believe that electronic description of the technology of biologically active additives in accordance with international CALS-standard ISO-10303 (STEP) enables to increase sales of new equipment.
Content may be subject to copyright.
CHEMICAL ENGINEERING TRANSACTIONS
VOL. 43, 2015
A publication of
The Italian Association
of Chemical Engineering
Online at www.aidic.it/cet
Chief Editors:
Sauro Pierucci, Jiří J. Klemeš
Copyright © 2015, AIDIC Servizi S.r.l.,
ISBN 978-88-95608-34-1; ISSN 2283-9216
Development of the CALS-Technology of Drying-
Agglomeration Process in Production of Biologically Active
Additives of the New Generation
Arkadiy Bessarabov*, Aleksey Kvasyuk, Tatiana Stepanova, Ekaterina
Sudarikova, Andrey Vendilo
R&D Centre "Fine Chemicals", Krasnobogatyrskaya st. 42, Moscow 107564, Russian Federation
bessarabov@nc-mtc.ru
At the present time, as a promising information technology, methods of the Continuous Acquisition and Life
Cycle Support (CALS) concept are widely implemented (Bessarabov et al., 2012). The CALS concept is based
on the complex of the unified information models and the standardization of methods for information access
and correct information interpretation according to the international standard ISO 10303 (STEP). A series of
CALS projects were developed for a number of technologies for producing special-purity substances
(Bessarabov et al., 2007) and waste utilization (Kvasyuk et al., 2012); however, in all the cases, CALS
methods were used only to create the project documentation.
1. Application of the CALS concept in development of the information systems
The essence of the concept of CALS is the application of the principles and technologies of information
support at all stages of the lifecycle of products based on the use of an integrated information system. It
provides a uniform way of managing processes and interaction of all participants in this cycle: customers
(including government agencies and departments), suppliers (producers) of goods, maintenance and repair
personnel (Saaksvuori, Immonen, 2010). These principles and techniques are implemented in accordance
with the requirements of the international standards governing rules of governance and interaction mainly
through the electronic data interchange.
The life cycle of products includes a number of stages, starting from the origins of the new product idea prior
to its disposal at end of useful life. These include the stages of marketing research, design, technological
preparation of production, actual production, after-sales service and maintenance products, and safe
environmentally friendly recycling (Lam et al., 2011).
There are own targets at all stages of the life cycle. The participants of the life cycle strive to achieve goals
with maximum efficiency. At the stages of design, technological preparation of production and manufacturing it
is necessary to ensure compliance with the requirements of the manufactured product at a given degree of
reliability of the product and minimize the time and money that is necessary for success in the competitive
struggle in the conditions of market economy. The concept of efficiency covers not only the reduction of
production costs and shorten design and production, but also the provision of facilities development and cost
reductions on future products. The operation requirements are of particular importance for complex products,
for example, in industries such as organic or inorganic chemistry.
Integrated information environment is the basis, the core of CALS is a distributed data repository that exists in
a networked computer system, covering (ideally) all services and departments, related to the processes of the
life cycle of products. A single system of rules of representation, storage and exchange of information
operates in an integrated information environment. Information processes that accompany and support of the
product life cycle at all stages flow in an integrated information environment in accordance with these rules.
There is the main principle of CALS concept: information, once incurred at any stage of the life cycle, is stored
DOI: 10.3303/CET1543025
Please cite this article as: Bessarabov A., Kvasyuk A., Stepanova T., Sudarikova E., Vendilo A., 2015, Development of the cals-technology of
drying-agglomeration process in production of biologically active additives of the new generation, Chemical Engineering Transactions, 43,
145-150 DOI: 10.3303/CET1543025
145
in an integrated information environment and becomes available to all participants in this and other phases (in
accordance with their existing rights to the use of this information). This avoids duplication, conversion and
unauthorized modification of data, and errors associated with these procedures, and to reduce labor costs,
time and financial resources.
In an integrated information environment information is created, converted, stored and transmitted from one
participant in the life cycle to another with the help of application software, which include systems
CAE/CAD/CAM, PDM, MRP/ERP (Atkinson, 2013), SCM (Jacobs et al., 2011) and other.
The main content of CALS, fundamentally distinguishes this concept from others, constitutes basic principles
and technologies that are implemented (fully or partially) during the lifecycle of any product, regardless of its
purpose and the physical incarnation.
Different kinds of management can be classified to the underlying technologies: management of projects,
product configuration, integrated information environment, quality, work streams, changes in industrial and
organizational structures.
Within the problem of CALS it is extremely urgent task for real enterprises to make a transition to a truly
paperless technologies for the design, manufacture and operation of products. For this transition, an
appropriate legal framework that defines the use of electronic documents and electronic digital signature
should be employed. An important direction is to develop methods and software solutions in the field of
integrated logistics support of high technology products.
Subject of CALS are methods and means as between the different automated systems and their subsystems
and automated systems, taking into account all their support. Almost synonymous with CALS in this sense is
PLM (Product Lifecycle Management), widely used in recent times by manufacturers of automated systems
(Stark, 2011).
In the narrow sense CALS is a technology of integration of various automated systems with their linguistic,
information, software, mathematical, methodological, technical and organizational support.
The linguistic support of CALS includes languages and data formats of industrial products and processes used
for the representation and exchange of information between automated systems and their subsystems at
different stages of the product life cycle.
Information support consists of a database including information about industrial products, used by different
systems in the process of design, production, operation and recycling. Part of the information security also
includes a series of international and national CALS standards and specifications.
CALS software systems (Bessarabov et al., 2010) are designed to support a single information space of the
lifecycle stages of a product. This is primarily a document management system and document management,
PDM system, development tools, interactive electronic technical manuals, and some others.
Mathematical support of CALS includes methods and algorithms to create and use models of interaction
between different systems of CALS-technologies. Among these methods, first and foremost, you should call
the methods of simulation of complex systems, methods, process planning and resource allocation.
Methodical maintenance of CALS presents methods of processes, such as parallel (combined) design and
production, structuring of complex objects, their functional and information modeling, object-oriented design,
the creation of ontology applications.
Technical maintenance of CALS includes hardware for receiving, storing, processing, data visualization with
information support of the products. The interaction of different parts of virtual enterprises and systems that
support different stages of the lifecycle occurs via the data link and network switching equipment. It is widely
used features of the Internet and Web technologies. However, the techniques employed are not specific for
the CALS-technologies.
Organizational maintenance of CALS presents various types of documents, a set of agreements and
regulations governing the roles and responsibilities of participants in the life cycle of industrial products.
The use of information CALS-technologies allows you to reduce: direct costs for design (10% to 30%); time of
product development (40% to 60%); time for introduction of new products to the market (25% to 75%);
proportion of defects and the amount of design changes (23% to 73%); expenses for the preparation of
technical documentation (up to 40%); costs for development of the operational documentation (up to 30%).
The mentioned advantages of CALS-technologies have necessitated their use in this work.
2. Information CALS-model of drying-agglomeration process in production of biologically
active additives
In this work, using CALS methods, an information model was elaborated which includes all the steps
(marketing, design, production, service and repair, and realization and sale) of the technology of producing
biologically active additives of a new generation from an extract of medicinal herbs and gelatin-starch
146
complex. In recent years, biologically active food additives - therapeutic and prophylactic preparations
produced from herbal raw material - have successfully competed with the synthetic drugs.
Let us sequentially consider elements of the information model that correspond to various steps of the
technology of biologically active additives (Bessarabov et al., 2004).
On the basis of marketing research results, at the marketing step, two information-analytical blocks were
formed: consumer characteristics and risk factors. Each of the blocks included lower-level parameters, whose
analysis gives a complete pattern of the entire analytical block. For convenience of using the system, the
parameters were inputted in text and table formats, as well as in graphic form. As basic consumer
characteristics, the income, age, and sex distributions of consumers were analyzed.
In this block, the reasons for buying biologically active additives and the main factors affecting the purchase
decision were also studied. In the block of risk factors, an analysis was undertaken regarding the possibility of
a change in tax laws and concerning inflation and competition, market capacity, degree of import substitution,
and prices for similar products. At the marketing step, a conclusion was drawn about the expedience and
prospects of developing technology and equipment for producing biologically active additives of new
generation.
At the design step (Figure 1), the initial data for design were analyzed, which contain information on six basic
stages: grinding of medicinal raw material, extraction, concentration, mixing, drying--agglomeration, and
packing. Particular attention was given to the limiting stage-drying-agglomeration.
The main methods for drying (Chen and Putranto, 2013) of biologically active additives were analyzed; these
are spray drying, fluidized-bed drying, infrared drying, and drying in a vacuum dryer equipped with a rake
agitator.
It was shown that the equipment considered is inefficient if the product contains astringent substances
(fructose, lactose, gelatin-starch complex, and others), which, during drying-agglomeration, form clots, stick to
moving parts and the housing of the apparatus, and can render the apparatus inoperative.
Figure 1: CALS Project element at the design step (basic stages of the technology of biologically active
additives).
147
Figure 2: CALS Project element at the design step (dryer-agglomerator design).
Therefore, a continuous convective agitator dryer was proposed, which gives a product of required quality and
given particle size distribution (Figure 2). At the design step, four variants of agitator design were considered
(Figure 3). The ultimately chosen variant was the design that ensured required product quality at minimal
energy consumption, with the agitator of this design being constructed at minimal material and labor
expenditures. Three methods for introducing a heat-transfer medium were analyzed, and the optimal variant
ensuring the maximal uniformity and efficiency of heat transfer was chosen. Intermediate and final variants
described in text and graphic files were included into the CALS project.
Figure 3: CALS Project element at the design step (agitator design).
148
Figure 4: CALS Project element at the step of service of the dryer-agglomerator.
At the production step, technical documentation of extractors, dryers-agglomerators, and other equipment was
analyzed by industrial equipment manufacturing plants.
At the service step, technical information on the main stages (switching on, operation, switching off, washing)
of service of extractors, dryers-agglomerators (Figure 4), and other equipment was introduced.
Information at the repair step (Figure 5) was structured at three levels: trouble-cause-troubleshooting. The
developed module enables one to promptly, in dialog mode, select the optimal variant of troubleshooting.
Figure 5: CALS Project element at the step of repair of the dryer-agglomerator.
149
The step of realization and sale included product promotion to market (advertising in printed and electronic
mass media; participation in exhibitions, contests, tenders, etc.) and also analysis of information on the use of
the developed equipment not only in the technology of biologically active additives but also in the chemical
and pharmaceutical industries.
Under the conditions of the rapid development of the Internet with allowance for its potentialities, one of the
elements of this step was the development of the information web site of OOO Ob’edinenie IREA-PENZMASh,
the parent organization in the production of the biologically active additives considered in this work and
promising equipment for drying highly viscous extracts of medicinal raw material. On the basis of the
accumulated information, the optimal structure of the web site was developed, necessary information contents
were analyzed, and a system for rapidly surfing the site was implemented. The site combined two main
Internet systems: ftp (file transfer protocol) and http (hypertext transfer protocol). The http system was used to
illustratively and conveniently store information, to structure information, and to easily move between sections.
The ftp service was used for the data (file) storage and exchange.
Basic elements of the CALS project for the technology of biologically active additives were placed on the
Internet on the CALS-khimiya (CALS Chemistry) web site in the Pilot Projects section. Also here are links to
CALS files containing data in STEP exchange format. The files themselves are located on an ftp server and
are accessed via ftp protocol with an ordinary web-browser. This scheme (in which information is place in ftp
rather than http) was chosen for new files to be conveniently uploaded to the website by various developers,
rather than solely by the server administrator. This web site is one of the promising elements for training
scientists and specialists of industrial plants in implementing CALS methods to the chemical industry.
3. Conclusions
The results of this work were implemented at plants of the OOO Ob’edinenie IREA-PENZMASh. The
developed CALS documentation significantly reduces the service, maintenance, and repair costs. According to
predictions of specialists soon it will be impossible to sell high-tech products in the international market without
electronic documentation created in compliance with CALS standards (ISO 10303 STEP). Therefore, one can
believe that the electronic description of the technology of biologically active additives in accordance with the
international CALS standard ISO 10303 (STEP) enables one to increase sales of the new equipment.
References
Atkinson R., 2013, Enterprise Resource Planning (ERP) The Great Gamble: An Executive's Guide to
Understanding an ERP Project. XLIBRIS, Bloomington, USA
Bessarabov A., Klemes J., Kvasyuk А., Bulatov I., 2010, CALS software tool system for marketing researches
results of phosphoric industry waste utilization, Chemical Engineering Transactions, 19, 439-444, DOI:
10.3303/CET1019072
Bessarabov A.M., Malyshev R.M., Dem’yanyuk A.Yu, 2004, CALS-Based Information Model of the
Technology of Biologically Active Additives of a New Generation, Theoretical Foundations of Chemical
Engineering, 38(3), 322-327.
Bessarabov A.M., Ponomarenko A.N., Ivanov M.Ya., 2007, CALS Information Technologies (ISO-10 303
STEP) in Development of Plasmochemical Processes for Synthesis of Ultrapure Ultradispersed Oxides.
Russian Journal of Applied Chemistry, 80(1), 13-18.
Bessarabov A., Zhekeyev M., Sandu R., Kvasyuk А., Stepanova T., 2012, Development of HSE management
CALS-system for waste utilization of phosphoric industry of Russia and Kazakhstan, Chemical Engineering
Transactions, 26, 513-518, DOI: 10.3303/CET1226086
Chen X.D., Putranto A., 2013, Modelling Drying Processes: A Reaction Engineering Approach. Cambridge
University Press, Cambridge, England
Jacobs F.R., Berry W., Whybark D.C., Vollmann T., 2011, Manufacturing Planning and Control for Supply
Chain Management. McGraw-Hill Professional, New York, USA
Kvasyuk A., Koltsova E., Bessarabov A., Bulatov I., Stepanova T., 2012, CALS-technology for production of
dibasic lead phosphite in phosphoric sludge utilization, Chemical Engineering Transactions, 29, 853-858,
DOI: 10.3303/CET1229143
Lam H.L., Klemeš J.J., Kravanja Z., Varbanov P., 2011, Software Tools Overview: Process Integration,
Modelling and Optimisation for Energy Saving and Pollution Reduction, Asia-Pacific Journal of Chemical
Engineering, 6(5), 696-712, DOI: 10.1002/apj.469
Saaksvuori A., Immonen A., 2010, Product Lifecycle Management. 3rd ed. Springer, New York, USA
Stark J., 2011, Product Lifecycle Management: 21st Century Paradigm for Product Realisation. 2nd ed.
Springer, New York, USA
150
ResearchGate has not been able to resolve any citations for this publication.
Article
Full-text available
Phosphoric sludge is the most harmful and dangerous of wastes in the manufacturing of phosphorus-containing products; rough estimates show that its aggregated volumes total millions of tons. Therefore utilisation of that waste is now an acute problem and it can notably contribute not only to national economies, but can also considerably improve environmental conditions. Development of industrial productions for processing of phosphoric sludge was carried out within the most modern and advanced system of computer support - CALS-technologies (Continuous Acquisition and Life cycle Support). The task of the CALS is transformation of product life cycle to highly automated process by re-structuring of business processes included into it. In development of prospective chemical manufacturings it is shown that CALS-technologies and the main CALS-standard ISO 10303 STEP offer a way of a solution of a problem of electronic representation of the design information by means of use of the standardized integrated description of a product. Within EC ECOPHOS № INCO-CT-2005-013359 project, marketing researches of the phosphoric industry waste utilization, system researches of innovative capacities of leading companies making and utilizing phosphorus-containing production wastes were carried out, and also the flexible two-product flowsheet of phosphoric sludge utilization obtaining of sodium phosphite and hypophosphite was developed. Previous works described the phosphite and hypophosphite utilisation. In the current work carried out under the contract of Ministry of Education and Science of Russia no. 11.519.11.5005, we considered the complex of three individual productions of phosphoric sludge utilization, including sodium phosphite and hypophosphite, and also phosphoric sludge processing through sodium phosphite to dibasic lead phosphite. In production of dibasic lead phosphite sodium phosphite obtained in flexible two-product manufacturing is used as raw materials. Therefore we developed the flexible three-product flowsheet for phosphoric sludge processing which allows to combine three manufacturings, namely sodium phosphite and hypophosphite, and dibasic lead phosphite. For unification of those individual productions, the flexibility principles were used. Flexible three-product manufacturing corresponds two attributes of the theory of flexible chemical and technological systems, i.e. has technological and chemical similarity. In terms of technological similarity, at the design stage, characteristic units of flexible two-product manufacturing were identified (FUS-1 and FUS-2 flexible switching units), as well as new FUS-3 and FUS-4 that allow obtaining of dibasic lead phosphite with minimum control efforts. The developed flexible scheme was put in the information CALS-project with all the technical characteristics, drawings of the used equipment, etc. The flowsheet includes 35 technological units, including: 10 combined units used in manufacturing of Pb•PbHPO3, Na2HPO3 and NaH2PO2, and 12 units for manufacturing only Pb•PbHPO3.
Article
Full-text available
The problem of phosphoric industry waste utilisation is one of the important aspects of the environmental protection in Russia and Kazakhstan as well as in some other countries world-wide. Effective solution of this problem requires using of the system analysis methods and the most modern information technologies. Therefore, the main purposes of our work are: the system analysis of the influence of innovative activity for environmental characteristics of the phosphoric industry of Russia, and also the development of the information technology for the rational phosphoric industry waste utilization of Kazakhstan. As a part of EC co-funded project ECOPHOS No. INCO-CT-2005-013359 had been developed of information technology tool for the HSE management of phosphoric industry of Russia and Kazakhstan based on CALS-concept (Continuous Acquisition and Life cycle Support). CALS-technologies (ISO 10303 standard) offer standardised software tool system for presentation of ecological information.
Article
Full-text available
During the development of prospective chemical productions it is shown, that CALS-technologies and the main CALS-standard ISO 10303 STEP offer the way to solve the problem of electronic presentation of all of the stages of lifecycle: marketing, design, production, exploitation (repair) and realization (sales). Not the least of the factors when creating the competitive production is the marketing research. Typical information CALS-system of marketing researches of phosphoric industry waste utilization was developed in our work. This research affects key parameters of the market: volumes, prices, forecasts as well as detailed aspects of applied technologies of existing waste processing. The main components of activity and development of the market in Russia, Kazakhstan, Ukraine and Greece are analyzed. The marketing research carried out has been structured in following categories of the top level: analysis of the raw material and processing market; analysis of waste processing technologies; analysis of the markets of waste utilization products. All the above categories have been included in the developed CALS-project. In the first category, «Analysis of the raw material and processing market» for each of the countries considered (Russia, Kazakhstan, Ukraine and Greece) the following four main subcategories are brought: producers of substances containing phosphorus (for example, in Russia); total waste accumulated within this or that country; existing government support of firms of phosphoric industry; cooperation with other countries. For the categories «Analysis of waste processing technologies» data on applied technologies of phosphoric sludge, phosphoric plaster and phosphoric slag processing are included. Subcategory «Phosphoric sludge processing» contains four sorts of utilization: burial, combustion, secondary processing and outsourcing. For each technology of utilization the information contains: characteristics of technology; advantages and disadvantages; cost and ecological aspects. Information about the products of utilization is brought to the third category of marketing research «Analysis of the markets of waste utilization products». Waste utilization products (phosphoric sludge, phosphoric plaster and phosphoric slag) were included into it, and, the most important, possible application of utilization products. Simplicity and efficiency of the user access to the available information at application of CALS-standards (ISO-10303 STEP) enables to expand qualitatively commodity markets of products and technologies of utilization, and also to capture a greater share of the market
Article
Full-text available
An information model of the technology of biologically active additives (BAA) of a new generation is presented which is based on the Continuous Acquisition and Life Cycle Support (CALS) concept. The information model includes typical computer structures: marketing, design, production, service and repair, and realization and sale.
Article
Full-text available
Information model of plasmochemical processes for synthesis of nano-and ultradispersed oxide materials was developed on the basis of the CALS concept (Continuous Acquisition and Life cycle Support) for the example of ultrapure tin oxides.
Article
This comprehensive summary of the state-of-the-art and the ideas behind the reaction engineering approach (REA) to drying processes is an ideal resource for researchers, academics and industry practitioners. Starting with the formulation, modelling and applications of the lumped-REA, it goes on to detail the use of the REA to describe local evaporation and condensation, and its coupling with equations of conservation of heat and mass transfer, called the spatial-REA, to model non-equilibrium multiphase drying. Finally, it summarises other established drying models, discussing their features, limitations and comparisons with the REA. Application examples featured throughout help fine-tune the models and implement them for process design, and the evaluation of existing drying processes and product quality during drying. Further uses of the principles of REA are demonstrated, including computational fluid dynamics-based modelling, and further expanded to model other simultaneous heat and mass transfer processes.
Article
The paper provides an overview based on an experience and applications of process integration, modelling and optimisation software tools. The first part reviews the design practice and supporting software tools. General purpose optimisation and modelling tools overviews have been available from conferences and publication (Klemeš, 1977; Friedler, 2009 and 2010; Klemeš et al., 2010; Lam et al., 2010). Those are categorised as (i) Process integration and retrofit analysis tools (ii) Flowsheeting simulation and (iii) General mathematical modelling suites with optimisation libraries. The second part covers assessment of tools which enable the generation of sustainable alternatives. They deal with waste, environment, energy and material depletion and production cost constrains. Emphasis of the sustainable process design tools is on (a) Evaluation of process viability under sustainable economic conditions (b) Synthesis of sustainable processes and supply chains (c) Process maintenance and life cycle analysis. The concluding part provides an overview of software tools development and the potential of the research based tools in solving the problem of sustainable process design.
Manufacturing Planning and Control for Supply Chain Management
  • F R Jacobs
  • W Berry
  • D C Whybark
  • T Vollmann
Jacobs F.R., Berry W., Whybark D.C., Vollmann T., 2011, Manufacturing Planning and Control for Supply Chain Management. McGraw-Hill Professional, New York, USA
Product Lifecycle Management Product Lifecycle Management: 21st Century Paradigm for Product Realisation
  • A Saaksvuori
  • A Immonen
Saaksvuori A., Immonen A., 2010, Product Lifecycle Management. 3rd ed. Springer, New York, USA Stark J., 2011, Product Lifecycle Management: 21st Century Paradigm for Product Realisation. 2nd ed. Springer, New York, USA
Enterprise Resource Planning (ERP) The Great Gamble: An Executive's Guide to Understanding an ERP Project
  • R Atkinson
Atkinson R., 2013, Enterprise Resource Planning (ERP) The Great Gamble: An Executive's Guide to Understanding an ERP Project. XLIBRIS, Bloomington, USA